Surveyor landing radar test program review Final report

Test program evaluation and modifications for Surveyor radar altimeter and Doppler velocity sensor syste

The trade cycle theories of R.G. Hawtrey and F.A. von Hayek, with particular reference to the role attributed by each to the rate of interest

It was originally intended that this essay should be confined to a study of interest alone, in the context of the trade cycle theories of R. G. Hawtrey and F. A. v. Hayek. However it was found that much of the significance of the rate of interest was lost unless changes in the rate were continuously related to the process of the cycle as a whole. There has, therefore, been inevitably a "widening" of the subject matter (perhaps at the sacrifice of "deepening"!) to include other aspects of their theories which, while not directly related to interest, nevertheless do help towards a clearer understanding of the context in which it is set. The writer is conscious of the omission of any discussion of the "Austrian" theory of capital as such, on which much of Hayek's approach to the trade cycle is based, but it was felt that to do justice to such a complex topic little short of a "thesis within a thesis" would have been adequate. The essay consists of three parts. The first two deal with the theories of Hawtrey and Hayek separately, while Part Three includes some general conclusions suggested by the discussion

Developmental design, fabrication, and test of acoustic suppressors for fans of high bypass turbofan engines

An analysis procedure was developed for design of acoustically treated nacelles for high bypass turbofan engines. The plan was applied to the conceptual design of a nacelle for the quiet engine typical of a 707/DC-8 airplane installation. The resultant design was modified to a test nacelle design for the NASA Lewis quiet fan. The acoustic design goal was a 10 db reduction in effective perceived fan noise levels during takoff and approach. Detailed nacelle designs were subsequently developed for both the quiet engine and the quiet fan. The acoustic design goal for each nacelle was 15 db reductions in perceived fan noise levels from the inlet and fan duct. Acoustically treated nacelles were fabricated for the quiet engine and quiet fan for testing. Performance of selected inlet and fan duct lining configurations was experimentally evaluated in a flow duct. Results of the tests show that the linings perform as designed

Attempts to Enrich the Parasite Fauna of the European Corn Borer in Minnesota

Four parasitic insect species were tested in laboratory experimentation for adaptability to the European corn borer (ECB). Apanreles sesamiae, Apanteles flavipes and Chelonus knabi did not adapt to the ECB, Lixophaga diatraeae was able to survive on ECB. Three other species. Macrocentrus grandii, Eriborus terebrans and Lydella rhompsoni, all known parasites of ECB, were obtained and reared in the laboratory on ECB for propagation, release and ecological studies. Methodology for experimentation and propagation of parasites was described

Strongly-coupled quantum critical point in an all-in-all-out antiferromagnet

Dimensionality and symmetry play deterministic roles in the laws of Nature. They are important tools to characterize and understand quantum phase transitions, especially in the limit of strong correlations between spin, orbit, charge, and structural degrees of freedom. Using newly-developed, high-pressure resonant x-ray magnetic and charge diffraction techniques, we have discovered a quantum critical point in Cd2Os2O7 as the all-in-all-out (AIAO) antiferromagnetic order is continuously suppressed to zero temperature and, concomitantly, the cubic lattice structure continuously changes from space group Fd-3m to F-43m. Surrounded by three phases of different time reversal and spatial inversion symmetries, the quantum critical region anchors two phase lines of opposite curvature, with striking departures from a mean-field form at high pressure. As spin fluctuations, lattice breathing modes, and quasiparticle excitations interact in the quantum critical region, we argue that they present the necessary components for strongly-coupled quantum criticality in this three-dimensional compound

Parameter inference in mechanistic models of cellular regulation and signalling pathways using gradient matching

A challenging problem in systems biology is parameter inference in mechanistic models of signalling pathways. In the present article, we investigate an approach based on gradient matching and nonparametric Bayesian modelling with Gaussian processes. We evaluate the method on two biological systems, related to the regulation of PIF4/5 in Arabidopsis thaliana, and the JAK/STAT signal transduction pathway

Gravitational Laser Back-Scattering

A possible way of producing gravitons in the laboratory is investigated. We evaluate the cross section electron + photon $\rightarrow$ electron + graviton in the framework of linearized gravitation, and analyse this reaction considering the photon coming either from a laser beam or from a Compton back-scattering process.Comment: 11 pages, 2 figures (available upon request), RevTeX, IFT-P.03/9

A knowledge-based approach to configuration layout, justification, and documentation

The design, development, and implementation is described of a prototype expert system which could aid designers and system engineers in the placement of racks aboard modules on Space Station Freedom. This type of problem is relevant to any program with multiple constraints and requirements demanding solutions which minimize usage of limited resources. This process is generally performed by a single, highly experienced engineer who integrates all the diverse mission requirements and limitations, and develops an overall technical solution which meets program and system requirements with minimal cost, weight, volume, power, etc. This system architect performs an intellectual integration process in which the underlying design rationale is often not fully documented. This is a situation which lends itself to an expert system solution for enhanced consistency, thoroughness, documentation, and change assessment capabilities

The active metabolite of leflunomide, A77 1726, increases proliferation of human synovial fibroblasts in presence of IL-1β and TNF-α

Abstract.: Objective and design: Excessive synovial fibroblast (SF) proliferation is detrimental in rheumatoid arthritis. We therefore sought to determine the effects of A77 1726, the active metabolite of leflunomide, on SF proliferation. Methods: Human SFs were used. Cell proliferation was investigated using MTS assay, by 3H-thymidine incorporation and cell counts. Results: Whereas A77 1726 alone had no effects, it significantly increased the mitogenic effects of interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α). Cyclooxygenase inhibition might be at least partly involved, since indomethacin displayed similar effects, and since prostaglandin E2 inhibited SF proliferation. In contrast, the effect of A77 1726 did not appear to be mediated through depletion of the pyrimidine pool or inhibition of tyrosine kinases. Conclusion: A77 1726 displays proliferative effects in presence of IL-1β and TNF-α. Further elucidation of involved mechanisms may prove useful for the utilization of leflunomide, the development of related compounds or elaboration of new therapeutic strategie