Challenges and Lessons Learned: Moving From Image Database to Institutional Repository

Purpose– The purpose of this paper is to chronicle the Lamar Soutter Library\u27s effort to build an educational image database, and how the project developed into an institutional repository. Design/methodology/approach– The paper is divided into three phases and highlights the organizational, political, technological and resource issues that are unique to a specialized library with a medium-sized staff, lacking the resources of a traditional university campus. The case concludes with a list of barriers and facilitators to success and a summary of lessons learned. Findings– The paper finds that a library with limited staff, funding, and systems development resources can initiate and support an institutional repository. Facilitators of success include clear lines of authority, a strong champion, and the appropriate technology for the project. Originality/value – This paper serves as an example to libraries that are in the beginning phases of developing an institutional repository by discussing the barriers to and facilitators of success

A trait-based approach for predicting species responses to environmental change from sparse data : how well might terrestrial mammals track climate change?

Acknowledgements LS was supported by two STSMs by the COST Action ES1101 ”Harmonising Global Biodiversity Modelling“ (Harmbio), supported by COST (European Cooperation in Science and Technology). JMB and SMW were funded by CEH projects NEC05264 and NEC05100. JMJT and SCFP are grateful for the support of the Natural Environment Research Council UK (NE/J008001/1). LS, JAH and JMJT conceived the original idea. LS, JAH, JMB, TC & JMJT designed the study; LS collected the data; LS and TC performed the statistical analyses; LS conducted the integrodifference modelling assisted by JMB and SMW. LS conducted the individual-based modelling assisted by SCFP. LS led the writing supported by JMJT, JMB, SCFP, SMW, TC, JAH and GB.Peer reviewedPublisher PD

Low temperature removal of surface oxides and hydrocarbons from Ge(100) using atomic hydrogen

Germanium is a group IV semiconductor with many current and potential applications in the modern semiconductor industry. Key to expanding the use of Ge is a reliable method for the removal of surface contamination, including oxides which are naturally formed during the exposure of Ge thin films to atmospheric conditions. A process for achieving this task at lower temperatures would be highly advantageous, where the underlying device architecture will not diffuse through the Ge film while also avoiding electronic damage induced by ion irradiation. Atomic hydrogen cleaning (AHC) offers a low temperature, damage-free alternative to the common ion bombardment and annealing (IBA) technique which is widely employed. In this work, we demonstrate with xray photoelectron spectroscopy (XPS) that the AHC method is effective in removing surface oxides and hydrocarbons, yielding an almost completely clean surface when the AHC is conducted at a temperature of 250 ◦C. We compare the post-AHC cleanliness and (2 × 1) low energy electron diffraction (LEED) pattern to that obtained via IBA, where the sample is annealed at 600 ◦C. We also demonstrate that the combination of a sample temperature of 250 ◦C and atomic H dosing is required to clean the surface. Lower temperatures prove less effective in removal of the oxide layer and hydrocarbons, whilst annealing in ultra-high vacuum conditions only removes weakly bound hydrocarbons. Finally, we examine the subsequent H-termination of an IBA-cleaned sample using XPS, LEED and ultraviolet photoelectron spectroscopy (UPS) in order to examine changes in the work function of Ge(100) upon hydrogenation

Consensus: guidelines: best practices for detection, assessment and management of suspected acute drug-induced liver injury during clinical trials in patients with nonalcoholic steatohepatitis

BACKGROUND: The last decade has seen a rapid growth in the number of clinical trials enrolling patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NASH). Due to the underlying chronic liver disease, patients with NASH often require different approaches to the assessment and management of suspected drug-induced liver injury (DILI) compared to patients with healthy livers. However, currently no regulatory guidelines or position papers systematically address best practices pertaining to DILI in NASH clinical trials. AIMS: This publication focuses on best practices concerning the detection, monitoring, diagnosis and management of suspected acute DILI during clinical trials in patients with NASH. METHODS: This is one of several papers developed by the IQ DILI Initiative, comprised of members from 15 pharmaceutical companies, in collaboration with DILI experts from academia and regulatory agencies. This paper is based on extensive literature review, and discussions between industry members with expertise in drug safety and DILI experts from outside industry to achieve consensus on common questions related to this topic. RESULTS: Recommended best practices are outlined pertaining to hepatic inclusion and exclusion criteria, monitoring of liver tests, DILI detection, approach to a suspected DILI signal, causality assessment and hepatic discontinuation rules. CONCLUSIONS: This paper provides a framework for the approach to assessment and management of suspected acute DILI during clinical trials in patients with NASH

Capturing Students\u27 International Experiences: eScholarship@UMMS and International Medical Education

Type of engagement and location: eScholarship@UMMS (http://escholarship.umassmed.edu/intmeded/) is an electronic repository sponsored by the Lamar Soutter Library. The Library is collaborating with the Office of Medical Education’s International Medical Education initiative under the direction of Dr. Michael Godkin. Purpose/objective: The purpose of the collaboration is to provide an archive to preserve and promote clinical and language experiences of UMMS students serving in developing countries. Description: The Library is building a database of student trips that includes descriptions of sites and clinical experiences, photos, personal reflections, maps, and advice for future students. Library staff worked with Dr. Godkin to convert paper records into an electronic format and added metadata to enhance searching. Reports are organized by country and year, and are full-text searchable. Conclusion: eScholarship@UMMS offers an efficient and convenient means of promoting student interest in international medical education. More than 50 student trip reports from almost 20 countries have been entered into the database. In just four months the site has already had an impact and generated increased student interest. By archiving these trip reports, eScholarship@UMMS ensures that the information will be available for future UMMS students. Implications: eScholarship@UMMS supports the primary goals of the International Medical Education program: to develop linguistic, cultural and physical diagnosis skills and enable the students to better serve a rapidly expanding immigrant and refugee population in Massachusetts and the United States. Presented at the UMass Global Health Symposium, Shrewsbury, MA, on May 3-4, 2007

A Visual Impact Assessment Methodology for the National Park Service

As the National Park Service (NPS) set out to create a visual resource management program, the first major component was the development of a robust visual resource inventory (VRI) process to identify, locate, and assess high value views, both within and near NPS units, based on both scenic quality and the importance of the view to the visitor experience. The next component in the program has been the development of a visual impact assessment (VIA) process to understand how changes in the landscape— whether inside the park or beyond its boundaries—could impact the scenic quality of valued views and visitor experience of those views. This presentation will discuss the NPS VIA process and highlight results of field-testing. Units of the National Park System encompass a wide variety of landscape types and visual settings. Particular views are enjoyed not only for scenic qualities but also appreciated for their historic and cultural values. NPS incorporates visible elements of views into their interpretive and educational activities. As a result, the NPS VRI was designed to identify not only the visual qualities of views but also the other values that make views important to NPS and park visitors. The NPS VRI was also built to support VIAs, both for NPS projects and actions within NPS unit boundaries, and projects and activities beyond NPS unit boundaries, where NPS is a stakeholder rather than a permitting agency. The detailed information from the VRI provides a sound basis for articulating the full effects of a proposed project or activity, which may go far beyond measuring visual contrast and other more purely scenic aspects of visual impact. Building on the inventory process the NPS visual impact assessment (VIA) methodology identifies the expected level of visual change from a proposed project or activity, and assesses the likely effects of the change on scenic quality as determined in the VRI. The NPS VIA approach provides parks with information to pursue better planning and design for park projects and credible support for understanding and communicating the potential impacts of changes beyond park boundaries

Little angels: The mediation of parenting

This Article does not have an abstract

Transport behavior of holes in boron delta-doped diamond structures

Boron delta-doped diamond structures have been synthesized using microwave plasma chemical vapor deposition and fabricated into FET and gated Hall bar devices for assessment of the electrical characteristics. A detailed study of variable temperature Hall, conductivity, and field-effect mobility measurements was completed. This was supported by Schr€dinger-Poisson and relaxation time o calculations based upon application of Fermi’s golden rule. A two carrier-type model was developed with an activation energy of $0.2 eV between the delta layer lowest subband with mobility$1 cm2/Vs and the bulk valence band with high mobility. This new understanding of the transport of holes in such boron delta-doped structures has shown that although Hall mobility as high as 900 cm2/Vs was measured at room temperature, this dramatically overstates the actual useful performance of the device

Kappa-symmetric deformations of M5-brane dynamics

We calculate the first supersymmetric and kappa-symmetric derivative deformation of the M5-brane worldvolume theory in a flat eleven-dimensional background. By applying cohomological techniques we obtain a deformation of the standard constraint of the superembedding formalism. The first possible deformation of the constraint and hence the equations of motion arises at cubic order in fields and fourth order in a fundamental length scale $l$. The deformation is unique up to this order. In particular this rules out any induced Einstein-Hilbert terms on the worldvolume. We explicitly calculate corrections to the equations of motion for the tensor gauge supermultiplet.Comment: 17 pages. Additional comments in section