Glassy Spin Dynamics in Non-Fermi-Liquid UCu_{5-x}Pd_x, x = 1.0 and 1.5

Local f-electron spin dynamics in the non-Fermi-liquid heavy-fermion alloys UCu_{5-x}Pd_x, x = 1.0 and 1.5, have been studied using muon spin-lattice relaxation. The sample-averaged asymmetry function Gbar(t) indicates strongly inhomogeneous spin fluctuations, and exhibits the scaling Gbar(t,H) = Gbar(t/H^\gamma) expected from glassy dynamics. At 0.05 K \gamma(x=1.0) = 0.35 \pm 0.1, but \gamma(x=1.5) = 0.7 \pm 0.1. This is in contrast to inelastic neutron scattering results, which yield \gamma = 0.33 for both concentrations. There is no sign of static magnetism \gtrsim 10^{-3} \mu_B/U ion in either material above 0.05 K. Our results strongy suggest that both alloys are quantum spin glasses.Comment: 4 pages, 4 figures, to be published in Physical Review Letter

Supporting the routine collection of patient reported outcome measures in the National Clinical Audits for assessing cost-effectiveness. Work Package 1. What patient reported outcome measures should be used in the 2013/14 National Clinical Audit Programme.

To assess the appropriateness of the EQ-5D in 13 specified conditions (inflammatory bowel disease (IBD), epilepsy, diabetes, bowel cancer, head and neck cancer, psychological therapies, schizophrenia, dementia, cardiac arrhythmia, heart failure, coronary angioplasty, acute coronary syndrome, adult cardiac surgery); identify what measures may be used when the EQ-5D is not appropriate; identify if fields in corresponding National Clinical Audits (NCA) will suffice to conduct economic evaluations; present recommendations and future research questions in this area

The cost-effectiveness of changes to the care pathway used to identify depression and provide treatment amongst people with diabetes in England: a model-based economic evaluation.

BACKGROUND: Diabetes is associated with premature death and a number of serious complications. The presence of comorbid depression makes these outcomes more likely and results in increased healthcare costs. The aim of this work was to assess the health economic outcomes associated with having both diabetes and depression, and assess the cost-effectiveness of potential policy changes to improve the care pathway: improved opportunistic screening for depression, collaborative care for depression treatment, and the combination of both. METHODS: A mathematical model of the care pathways experienced by people diagnosed with type-2 diabetes in England was developed. Both an NHS perspective and wider social benefits were considered. Evidence was taken from the published literature, identified via scoping and targeted searches. RESULTS: Compared with current practice, all three policies reduced both the time spent with depression and the number of diabetes-related complications experienced. The policies were associated with an improvement in quality of life, but with an increase in health care costs. In an incremental analysis, collaborative care dominated improved opportunistic screening. The incremental cost-effectiveness ratio (ICER) for collaborative care compared with current practice was £10,798 per QALY. Compared to collaborative care, the combined policy had an ICER of £68,017 per QALY. CONCLUSIONS: Policies targeted at identifying and treating depression early in patients with diabetes may lead to reductions in diabetes related complications and depression, which in turn increase life expectancy and improve health-related quality of life. Implementing collaborative care was cost-effective based on current national guidance in England

Homdyn Study for the Lcls RF Photo-Injector

The authors report the results of a recent beam dynamics study, motivated by the need to redesign the LCLS photoinjector, that led to the discovery of a new effective working point for a split RF photoinjector. The HOMDYN code, the main simulation tool adopted in this work, is described together with its recent improvements. The new working point and its LCLS application is discussed. Validation tests of the HOMDYN model and low emittance predictions, 0.3 mm-mrad for a 1 nC flat top bunch, are performed with respect to the multi-particle tracking codes ITACA and PARMELA

Photoinjector design for the LCLS

The design of the Linac Coherent Light Source assumes that a low-emittance, 1-nC, 10-ps beam will be available for injection into the 15-GeV linac. The proposed rf photocathode injector that will provide a 150-MeV beam with rms normalized emittances of 1 mm in both the transverse and longitudinal dimensions is based on a 1.6-cell S-band rf gun that is equipped with an emittance compensating solenoid. The booster accelerator is positioned at the beam waist coinciding with the first emittance maximum and is provided with an accelerating gradient of ~25 MeV/m, i.e., the "new working point." The uv pulses required for cathode excitation will be generated by tripling the output of a Ti:sapphire laser system consisting of a highly stable cw mode-locked oscillator and two bow-tie amplifiers pumped by a pair of Q-switched Nd:YAG lasers. The large bandwidth of the Ti:sapphire system accommodates the desired temporal pulse shaping. Details of the design and the supporting simulations are presented.Comment: 13 pages (double spaced), 4 figures, contributed to The 23rd International Free Electron Laser Conference, Darmstadt, Germany, 20-24 August 200