1,198 research outputs found

    Guided Stereo Matching

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    Stereo is a prominent technique to infer dense depth maps from images, and deep learning further pushed forward the state-of-the-art, making end-to-end architectures unrivaled when enough data is available for training. However, deep networks suffer from significant drops in accuracy when dealing with new environments. Therefore, in this paper, we introduce Guided Stereo Matching, a novel paradigm leveraging a small amount of sparse, yet reliable depth measurements retrieved from an external source enabling to ameliorate this weakness. The additional sparse cues required by our method can be obtained with any strategy (e.g., a LiDAR) and used to enhance features linked to corresponding disparity hypotheses. Our formulation is general and fully differentiable, thus enabling to exploit the additional sparse inputs in pre-trained deep stereo networks as well as for training a new instance from scratch. Extensive experiments on three standard datasets and two state-of-the-art deep architectures show that even with a small set of sparse input cues, i) the proposed paradigm enables significant improvements to pre-trained networks. Moreover, ii) training from scratch notably increases accuracy and robustness to domain shifts. Finally, iii) it is suited and effective even with traditional stereo algorithms such as SGM.Comment: CVPR 201

    Muscular Christianity in 19th-Century Periodicals

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    Doing interlanguage analysis in school contexts

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    The aim of this chapter is to discuss these issues, by reporting on a project aimed at bringing interlanguage analysis to school. The project involved several teachers at different levels, from kindergarten to middle school, as part of wider teacher-training and action-research schemes. Teachers were involved in collecting data and in their subsequent analysis based on the notion of interlanguage. These procedures were designed so that they could be implemented in everyday school settings. The main goal was formative assessment, in the more usual sense of being oriented to improving didactic strategies, but also in the sense of being part of teacher training

    A typology of statements about discourse

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    The article presents a typology of statements that can be made about discourse data. The classification is based on two parameters: level of generality and level of interpretation. Each of these is operationalized into three discrete levels, to yield a nine-cell table containing types of statements going from the presenta- tion of a single case to the elaboration of complex general theories. The discus- sion is based on an extensive review of published research and on an empirical study on other-repetition in child second language discourse. The proposed clas- sification aims at clarifying a number of questions and possible misunderstand- ings about issues of interpretation, generalization, and quantification. It is shown that in some cases apparently opposed approaches actually make the same type of statements, simply using different terms and methodologies, whereas in other cases, the dispute is not on different methodological options, but rather on different types of statements altogether. Researchers are invited to be more explicit as regards their position in order to promote interdisciplinary dialog and facilitate cross-method comparisons

    Fatherhood and sperm DNA damage in testicular cancer patients

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    Testicular cancer (TC) is one of the most treatable of all malignancies and the management of the quality of life of these patients is increasingly important, especially with regard to their sexuality and fertility. Survivors must overcome anxiety and fears about reduced fertility and possible pregnancy-related risks as well as health effects in offspring. There is thus a growing awareness of the need for reproductive counseling of cancer survivors. Studies found a high level of sperm DNA damage in TC patients in comparison with healthy, fertile controls, but no significant difference between these patients and infertile patients. Sperm DNA alterations due to cancer treatment persist from 2 to 5 years after the end of the treatment and may be influenced by both the type of therapy and the stage of the disease. Population studies reported a slightly reduced overall fertility of TC survivors and a more frequent use of ART than the general population, with a success rate of around 50%. Paternity after a diagnosis of cancer is an important issue and reproductive potential is becoming a major quality of life factor. Sperm chromatin instability associated with genome instability is the most important reproductive side effect related to the malignancy or its treatment. Studies investigating the magnitude of this damage could have a considerable translational importance in the management of cancer patients, as they could identify the time needed for the germ cell line to repair nuclear damage and thus produce gametes with a reduced risk for the offspring

    Oncofertility and oncosexualityvin non-Hodgkin lymphoma and testicular cancer survivors

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    Background – Recently great attention was brought on long-term consequences of antineoplastic treatments, with special focus to reproductive and sexual health. Human testis can be severely damaged by chemo and radiotherapy but, while literature offers plenty of data regarding common malignancies in reproductive age such as testicular cancer and Hodgkin lymphoma, we know little about other neoplasias. Similarly, knowledge of male sexological alterations in cancer derives mainly from prostate cancer, which can hardly be generalized to other pathologies. Since little is known about Non-Hodgkin Lymphoma survivors’ fertility and there is incomplete information for Testicular Cancer survivors sexological counselling, the aim of this work was: (Study 1) to evaluate semen quality and fertility status before and after treatments of patients who underwent semen cryopreservation after the diagnosis of NHL; (Study 2) to evaluate the effect of TC after orchiectomy and provide a complete follow up in order to highlight possible post treatment short and long-term sexological alterations. Material and Methods – Patients attending the Laboratory of Seminology – Sperm Bank “Loredana Gandini” for sperm cryopreservation were selected for both studies after a careful medical history collection. Exclusion criteria were any comorbidity and any other known factor interfering with sperm parameters. For Study 1, 224 patients (mean age 32.7 ± 8.6 years) with diagnosis of Non-Hodgkin Lymphoma were selected, and semen analysis was performed at baseline (T0) and at least one follow up visit at 12 (T1), 24 (T2) or more than 24 months (T3; median 52 months); fertility status was ascertained with a dedicated questionnaire. For Study 2, 241 sexually active consecutive patients (mean age 31.3 ± 6.9 years) with recent diagnosis of testicular cancer were selected. IIEF questionnaire was completed for sexual function evaluation at baseline post-orchiectomy (T0) and at least one follow up control at 6 (T1), 12 (T2), 18 (T3), 24 (T4), 48 months (T5) and after 5 years (T6, median 96 months) after chemotherapy; 223 healthy controls were also recruited for IIEF scores comparisons. Moreover, both TC patient and controls underwent blood hormones analysis (FSH, LH, total Testosterone). Results – Study 1 – Non-Hodgkin Lymphoma patients showed pre-therapy mean semen parameters within WHO 2010 normal range. Longitudinal post-therapy evaluation showed that sperm parameters significantly worsened at T1 compared to T0 (p < 0.001). Total sperm number at T2 remained significantly worse than T0 (p = 0.040) whereas it returned to values comparable to baseline at T3. Progressive motility and abnormal forms returned comparable to baseline at T2. 13.7% of survivors were azoospermic at T3. Permanent spermatogenesis impairment was associated with pelvic radiotherapy (OR 14.54, 95% CI 1.90 – 111.28) and treatment intensification for bone marrow transplant (33% azoospermia at T3). Regarding fertility, 14/22 pts who desired children were able to achieve fatherhood either through natural fertility (2 pts) or through ART (12 pts). Study 2 – Baseline prevalence of erectile dysfunction is 37.8% in TC pts vs 9.9% in healthy controls (p < 0.001). IIEF-15 baseline scores were significantly worse in TC group compared to controls (p < 0.001), with the exception of the orgasmic function domain (p = 0.334). Post-chemotherapy evaluation showed that erectile function improves significantly at T2 (T0 vs T2; p < 0.001) with further improvements at T3 and T4 compared to baseline (T0 vs T3: p = 0.014; T0 vs T4: p = 0.002). However, we detected an increase in erectile dysfunction prevalence at T5 with a significant reduction of erectile function domain scores, which seemed to persist at T6. Compared to controls, erectile function remains significantly worse at T1 then return comparable to healthy controls. Sexual desire, intercourse satisfaction and general satisfaction showed trends of improvement from baseline but remained significantly worse compared to controls for the whole duration of the study. No significant variation of the orgasmic function was detected against both baseline values and controls. The evaluation of sexual hormones revealed that prevalence of biochemical hypogonadism was 5.4% in the TC group. There were no hypogonadal patients in CTR group. Total testosterone in post-orchidectomy patients (T0) is significantly lower than controls (p < 0.001), but no significant variation was detected at T1 and T2. Finally, no significant correlation was detected between total testosterone levels and scores of any IIEF15 domain. Discussion – Study 1 demonstrates that Non-Hodgkin Lymphoma survivors undergoing intensive treatments and pelvic radiotherapy risk severe and permanent impairment of spermatogenesis. However, routine NHL chemotherapy regimens are compatible with spermatogenesis recovery after 2 years from the end of treatments and, while average sperm parameters may not fully return to pretreatment values, more than a half (63%) of patient who actively desire fatherhood can conceive either through natural conception or ART. Similarly, for Testicular Cancer survivors we confirm the presence of erectile dysfunction and impairment of sexual desire and satisfaction compared to a healthy population with improvements expected within one year from the end of the treatments. Absence of clear correlations with biochemical hypogonadism suggests that psychological burden following cancer diagnosis and treatments may play an important role. Information from these studies is of extreme importance since it will allow to increase the effectiveness of patients’ counseling interventions in an oncofertility service

    An Approach to Assessing the Linguistic Difficulty of Tasks

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    This article proposes an approach to assessing the linguistic difficulty of tasks, that is, the linguistic features involved in performing a communicative task that may make it more or less challenging for language learners. The procedure follows the methodology proposed by Pallotti (2019) for operationalizing task interactional difficulty. This consists, firstly, in identifying what linguistic-communicative features are particularly difficult for language learners, based on previous research showing that they appear late in the course of acquisition. Secondly, native speakers\u2019 performance is observed in order to determine which tasks most involve these difficult linguistic features. The dimensions observed in this study concern lexical diversity and sophistication, morphological complexity, and length and depth of syntactic constructions. Data come from 10 native speakers of Italian performing 5 communicative tasks. Results show that different dimensions of linguistic difficulty are relatively independent of each other, and that inter- individual variation is rather limited as regards the lexicon and morphology, but more pronounced for syntax. Implications for SLA research, Task-Based Language Teaching and Task-Based Language Assessment are discussed
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