On the nonlinearity interpretation of q- and f-deformation and some applications

q-oscillators are associated to the simplest non-commutative example of Hopf algebra and may be considered to be the basic building blocks for the symmetry algebras of completely integrable theories. They may also be interpreted as a special type of spectral nonlinearity, which may be generalized to a wider class of f-oscillator algebras. In the framework of this nonlinear interpretation, we discuss the structure of the stochastic process associated to q-deformation, the role of the q-oscillator as a spectrum-generating algebra for fast growing point spectrum, the deformation of fermion operators in solid-state models and the charge-dependent mass of excitations in f-deformed relativistic quantum fields.Comment: 11 pages Late

Electron Neutrino and Antineutrino Appearance in the Full MINOS Data Sample

We report on v(e) and (v) over bar (e) appearance in v(mu) and (v) over bar (mu) beams using the full MINOS data sample. The comparison of these v(e) and (v) over bar (e) appearance data at a 735 km baseline with theta(13) measurements by reactor experiments probes delta, the theta(23) octant degeneracy, and the mass hierarchy. This analysis is the first use of this technique and includes the first accelerator long-baseline search for (v) over bar (mu) -\u3e (v) over bar (e). Our data disfavor 31% (5%) of the three-parameter space defined by delta, the octant of the theta(23), and the mass hierarchy at the 68% (90%) C.L. We measure a value of 2sin(2)(2 theta(13))sin(2)(theta(23)) that is consistent with reactor experiments. DOI: 10.1103/PhysRevLett.110.17180

Observation of seasonal variation of atmospheric multiple-muon events in the MINOS Near and Far Detectors

We report the first observation of seasonal modulations in the rates of cosmic ray multiple-muon events at two underground sites, the MINOS Near Detector with an overburden of 225 mwe, and the MINOS Far Detector site at 2100 mwe. At the deeper site, multiple-muon events with muons separated by more than 8 m exhibit a seasonal rate that peaks during the summer, similar to that of single-muon events. In contrast and unexpectedly, the rate of multiple-muon events with muons separated by less than 5-8 m, and the rate of multiple-muon events in the smaller, shallower Near Detector, exhibit a seasonal rate modulation that peaks in the winter

Precision measurement of the speed of propagation of neutrinos using the MINOS detectors

We report a two-detector measurement of the propagation speed of neutrinos over a baseline of 734 km. The measurement was made with the NuMI beam at Fermilab between the near and far MINOS detectors. The fractional difference between the neutrino speed and the speed of light is determined to be (v/c - 1) = (1.0 +/- 1.1) x 10(-6), consistent with relativistic neutrinos

Measurement of the multiple-muon charge ratio in the MINOS Far Detector

The charge ratio, R-mu = N mu + / N mu-, for cosmogenic multiple-muon events observed at an underground depth of 2070 mwe has been measured using the magnetized MINOS Far Detector. The multiple-muon events, recorded nearly continuously from August 2003 until April 2012, comprise two independent data sets imaged with opposite magnetic field polarities, the comparison of which allows the systematic uncertainties of the measurement to be minimized. The multiple-muon charge ratio is determined to be R mu = 1.104 + / - 0.006(stat)(-0.010)( + 0.009) (syst). This measurement complements previous determinations of single-muon and multiple-muon charge ratios at underground sites and serves to constrain models of cosmic-ray interactions at TeV energies

Study of quasielastic scattering using charged-current nu(mu)-iron interactions in the MINOS near detector

Kinematic distributions from an inclusive sample of 1.41 x 10(6) charged-current nu(mu) interactions on iron, obtained using the MINOS near detector exposed to a wide-band beam with peak flux at 3 GeV, are compared to a conventional treatment of neutrino scattering within a Fermi gas nucleus. Results are used to guide the selection of a subsample enriched in quasielastic nu Fe-mu interactions, containing an estimated 123,000 quasielastic events of incident energies 1 \u3c E-nu \u3c 8 GeV, with \u3c E-nu \u3e = 2.79 GeV. Four additional subsamples representing topological and kinematic sideband regions to quasielastic scattering are also selected for the purpose of evaluating backgrounds. Comparisons using subsample distributions in four-momentum transfer Q(2) show the Monte Carlo model to be inadequate at low Q(2). Its shortcomings are remedied via inclusion of a Q(2)-dependent suppression function for baryon resonance production, developed from the data. A chi-square fit of the resulting Monte Carlo simulation to the shape of the Q(2) distribution for the quasielastic-enriched sample is carried out with the axial-vector mass M-A of the dipole axial-vector form factor of the neutron as a free parameter. The effective M-A which best describes the data is 1.23(-0.09)(+0.13)(fit)(-0.15)(+0.12)(syst) GeV

Out of Equilibrium Thermal Field Theories - Finite Time after Switching on the Interaction - Wigner Transforms of Projected Functions

We study out of equilibrium thermal field theories with switching on the interaction occurring at finite time using the Wigner transforms (in relative space-time) of two-point functions. For two-point functions we define the concept of projected function: it is zero if any of times refers to the time before switching on the interaction, otherwise it depends only on the relative coordinates. This definition includes bare propagators, one-loop self-energies, etc. For the infinite-average-time limit of the Wigner transforms of projected functions we define the analyticity assumptions: (1) The function of energy is analytic above (below) the real axis. (2) The function goes to zero as the absolute value of energy approaches infinity in the upper (lower) semiplane. Without use of the gradient expansion, we obtain the convolution product of projected functions. We sum the Schwinger-Dyson series in closed form. In the calculation of the Keldysh component (both, resummed and single self-energy insertion approximation) contributions appear which are not the Wigner transforms of projected functions, signaling the limitations of the method. In the Feynman diagrams there is no explicit energy conservation at vertices, there is an overall energy-smearing factor taking care of the uncertainty relations. The relation between the theories with the Keldysh time path and with the finite time path enables one to rederive the results, such as the cancellation of pinching, collinear, and infrared singularities, hard thermal loop resummation, etc.Comment: 23 pages + 1 figure, Latex, corrected version, improved presentation, version accepted for publication in Phys. Rev.

Comparing the safety and efficacy of ruxolitinib in patients with Dynamic International Prognostic Scoring System low-, intermediate-1-, intermediate-2-, and high-risk myelofibrosis in JUMP, a Phase 3b, expanded-access study

Ruxolitinib, a potent Janus kinase 1/2 inhibitor, has demonstrated durable improvements in patients with myelofibrosis. In this analysis of the Phase 3b JUMP study, which included patients aged =18 years with a diagnosis of primary or secondary myelofibrosis, we assessed the safety and efficacy of ruxolitinib in patients stratified by Dynamic International Prognostic Scoring System (DIPSS) risk categories. Baseline characteristic data were available to assess DIPSS status for 1844 of the 2233 enrolled patients; 60, 835, 755, and 194 in the low-, intermediate (Int)-1-, Int-2-, and high-risk groups, respectively. Ruxolitinib was generally well tolerated across all risk groups, with an adverse-event (AE) profile consistent with previous reports. The most common hematologic AEs were thrombocytopenia and anemia, with highest rates of Grade =3 events in high-risk patients. Approximately, 73% of patients experienced =50% reductions in palpable spleen length at any point in the =24-month treatment period, with highest rates in lower-risk categories (low, 82.1%; Int-1, 79.3%; Int-2, 67.1%; high risk, 61.6%). Median time to spleen length reduction was 5.1 weeks and was shortest in lower-risk patients. Across measures, 40%–57% of patients showed clinically meaningful symptom improvements, which were observed from 4 weeks after treatment initiation and maintained throughout the study. Overall survival (OS) was 92% at Week 72 and 75% at Week 240 (4.6 years). Median OS was longer for Int-2-risk than high-risk patients (253.6 vs. 147.3 weeks), but not evaluable in low-/Int-1-risk patients. By Week 240, progression-free survival (PFS) and leukemia-free survival (LFS) rates were higher in lower-risk patients (PFS: low, 90%; Int-1, 82%; Int-2, 46%; high risk, 15%; LFS: low, 92%; Int-1, 86%; Int-2, 58%; high risk, 19%). Clinical benefit was seen across risk groups, with more rapid improvements in lower risk patients. Overall, this analysis indicates that ruxolitinib benefits lower-risk DIPSS patients in addition to higher risk

Primary breast lymphoma: a consideration in an HIV patient when a mass is discovered by screening mammography: a case report

Primary Breast lymphoma is a rare lesion that has been reported in patients without HIV. However, Primary Breast lymphoma occurring in a patient with HIV has rarely been reported despite the fact that HIV infection is known to increase the propensity to develop certain types of lymphoma. We report a case of an HIV patient with breast lymphoma that was discovered by screening mammography while presenting our argument for more cautionary management in this patient population