110 research outputs found

    Determinação das áreas de potencial de riscos de precipitações intensas em Belo Horizonte.

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    A áreas urbanas têm sido objeto de estudos climatológicos por causa da formação de "ilhas de calor", entretanto, as chuvas intensas são as responsáveis por causar os principais desastres. Eventos extremos de precipitações têm aumentado significativamente nas últimas duas décadas no município de Belo Horizonte, ocasionando enchentes urbanas, desabamentos de casas e desmoronamentos. A instalação de uma rede de pluviômetros para a coleta de dados durante a estação chuvosa 2003/04 na região metropolitana, permitiu a análise espacial das precipitações, regionalização dos dados, elaboração de um mapa de regiões com alto potencial de chuvas intensas e a elaboração de alertas diários de tempestades severas

    Comparative effects of autochthonous single-strain and multistrain probiotics on the productive performance and disease resistance in Colossoma macropomum (Cuvier, 1818).

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    This study evaluated the effects of autochthonous single-strain and multi-strain (mix) probiotics on the zootechnical performance and sanitary conditions of juvenile neotropical fish. Fingerlings of tambaqui (Colossoma macropomum) were fed three diets of single-strain probiotics (two Enterococcus faecium strains and one Bacillus cereus autochthonous strain) and a multi-strain probiotic diet (a mix of three probiotic strains) for 120&#8201;days. After dietary supplementation, 90 tambaquis were intraperitoneally injected with Aeromonas hydrophila at a concentration of 1.8&#8201;×&#8201;108 &#8201;CFU·g&#8722;1. Clinical signs of disease, infectious intensity and accumulated mortality rates were evaluated. The use of diets containing probiotics, regardless of strain, enhanced productive performance from 90 experimental days (p<&#8201;0.05). The multi-strain probiotics reduced the presence of potentially pathogenic bacteria in the intestine. Fish fed probiotics showed improved resistance to A. hydrophila infection, while the diets containing B. cereus (an autochthonous probiotic) and multi-strain probiotic promoted the lowest mortality rates and higher leucocyte and thrombocyte counts (p<&#8201;0.05). The results revealed that the use of probiotics as a single autochthonous or multi-strain probiotic enhanced fish growth, prevented dysbiosis and increased disease resistance

    Comparative effects of using a single strain probiotic and multi-strain probiotic on the productive performance and disease resistance in Oreochromis niloticus.

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    The study was carried out to evaluate the effect of dietary supplementation of three probiotic strains in isolation and a multi-strain formulation (mix) on the rearing of tilapia, based on the parameters of productive performance and resistance to infection. A total of 240 juveniles of Oreochromis niloticus (6.71 ± 0.93 g and 61.88 ± 1.44 mm) were fed for 90 days with fish food containing two varieties of Enterococcus faecium and one variety of Bacillus cereus following therapeutic concentrations reported in the literature, and one multi-strain formulation containing the three organisms. After the period of food supplementation, 45 specimens were injected intraperi-toneally with 300 &#956;L of Streptococcus agalactiae at a lethal concentration of 1.7 × 107 CFU.g

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p&lt;0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p&lt;0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
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