The roles of news media as democratic fora, agenda setters, and strategic instruments in risk governance

This study analyzes news media’s role in governmental decision-making processes related to a gradually intensifying series of earthquakes resulting from gas drilling in the Netherlands, and catastrophic natural earthquakes in Italy. According to the risk governance actors interviewed in both cases, media play three roles, as: democratic fora, agenda setters, and strategic instruments. Media attention for risk can create ripple effects in governmental decision-making processes. However, media attention tends to be risk-event driven and focuses on direct newsworthy consequences of events. For ‘non-event risks’, or when newsworthiness after a risk-event fades, the media’s agenda setting and democratic fora roles are limited. This contributes to risk attenuation in society, potentially resulting in limited risk prevention and preparedness. Governmental actors report difficulties in using news media for strategic communication to facilitate risk governance because of media’s tendency towards sensationalism. Our research suggests that, in the governance of earthquake-risk news, media logic overrules other institutional logics only for a short while and not in the long run when the three roles of media do not reinforce each other

In vitro testing of estragole in HepG2 cells: Cytokinesis-block micronucleus assay and cell-cycle analysis

The alkenylbenzene estragole (systematic name, 1-allyl-4-methoxybenzene) is a natural component of essential oils from various spices and herbs, including fennel, and it is used as a food and beverage flavouring agent. Estragole has been reported to be hepatocarcinogenic at high doses in rodents. However, in a previous in vitro study, we found that estragole did not exhibit cytotoxic effects after 4 hours of exposure, nor did it induce DNA damage or apoptosis in human HepG2 hepatoblastoma cells. As fennel tea is widely used for symptomatic treatment of spasmodic gastrointestinal conditions in infants, we aimed at further assessing its safety in a different experimental setting. We thus searched for possible cytogenetic effects and interference with cell-cycle progression in the same human hepatoblastoma cell line. Estragole did not show any clastogenic/aneugenic activities in the cytokinesis-block micronucleus assay, and no effects on cell-cycle checkpoints were observed

Analysis of Deterioration in the Crypt of the Abbey of Montecorona with Integrated Methods

A study of the problem of deterioration in the crypt of the Abbey of Montecorona (Perugia, Northen Umbria-Italy) is proposed, with the aim to achieve a knowledge of the indoor and subsoil conditions. First of all we studied the microbial biodiversity of the crypt, analyzing the presence of microorganisms by microscopic and cultivation methods. Then we investigated the influence of the environment upon colonisation and growth of those micro-organisms, monitoring the microclimate, especially the thermo-hygrometric conditions. Various Ground Penetrating Radar (GPR) System surveys were carried out in order to localise archaeological remains and wet buried structures involved in the deterioration process and, by means a velocity analysis, we evaluated the underground water content. Microclimatic, biological and geophysical results were compared, in order to eliminate the ambiguity inherent each method. The results permits us to identify properly the causes of the deterioration in the crypt

New constituents of sweet Capsicum annuum L. fruits and evaluation of their biological activity

Four new acyclic diterpene glycosides named capsianosides (1-4), together with 12 known compounds, were isolated from the fresh sweet pepper fruits of Capsicum annuum L., a plant used as a vegetable food, spice, and external medicine. The chemical structures of new natural compounds, as well as their absolute configurations, were established by means of spectroscopic data including infrared, high-resolution mass spectrometry, and one-and two-dimensional nuclear magnetic resonance and by chemical derivatization. The known capsidiol (11) showed bacteriostatic properties in vitro against Helicobacter pylori with a minimum inhibitory concentration (MIC) of 200 mu g/mL when compared with the commercial drug metronidazole (MIC, 250 mu g/mL). Some purified components were also tested for their antioxidant activities