71 research outputs found

    A-posteriori provenance-enabled linking of publications and datasets via crowdsourcing

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    This paper aims to share with the digital library community different opportunities to leverage crowdsourcing for a-posteriori capturing of dataset citation graphs. We describe a practical approach, which exploits one possible crowdsourcing technique to collect these graphs from domain experts and proposes their publication as Linked Data using the W3C PROV standard. Based on our findings from a study we ran during the USEWOD 2014 workshop, we propose a semi-automatic approach that generates metadata by leveraging information extraction as an additional step to crowdsourcing, to generate high-quality data citation graphs. Furthermore, we consider the design implications on our crowdsourcing approach when non-expert participants are involved in the process<br/

    Modelling Knowledge about Software Processes using Provenance Graphs and its Application to Git-based Version Control Systems

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    Using the W3C PROV data model, we present a general provenance model for software development processes and, as an example, specialized models for git services, for which we generate provenance graphs. Provenance graphs are knowledge graphs, since they have defined semantics, and can be analyzed with graph algorithms or semantic reasoning to get insights into processes

    IGF-1, IGFBP-1, and IGFBP-3 Polymorphisms Predict Circulating IGF Levels but Not Breast Cancer Risk: Findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)

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    IGF-1 has been shown to promote proliferation of normal epithelial breast cells, and the IGF pathway has also been linked to mammary carcinogenesis in animal models. We comprehensively examined the association between common genetic variation in the IGF1, IGFBP1, and IGFBP3 genes in relation to circulating IGF-I and IGFBP-3 levels and breast cancer risk within the NCI Breast and Prostate Cancer Cohort Consortium (BPC3). This analysis included 6,912 breast cancer cases and 8,891 matched controls (n = 6,410 for circulating IGF-I and 6,275 for circulating IGFBP-3 analyses) comprised primarily of Caucasian women drawn from six large cohorts. Linkage disequilibrium and haplotype patterns were characterized in the regions surrounding IGF1 and the genes coding for two of its binding proteins, IGFBP1 and IGFBP3. In total, thirty haplotype-tagging single nucleotide polymorphisms (htSNP) were selected to provide high coverage of common haplotypes; the haplotype structure was defined across four haplotype blocks for IGF1 and three for IGFBP1 and IGFBP3. Specific IGF1 SNPs individually accounted for up to 5% change in circulating IGF-I levels and individual IGFBP3 SNPs were associated up to 12% change in circulating IGFBP-3 levels, but no associations were observed between these polymorphisms and breast cancer risk. Logistic regression analyses found no associations between breast cancer and any htSNPs or haplotypes in IGF1, IGFBP1, or IGFBP3. No effect modification was observed in analyses stratified by menopausal status, family history of breast cancer, body mass index, or postmenopausal hormone therapy, or for analyses stratified by stage at diagnosis or hormone receptor status. In summary, the impact of genetic variation in IGF1 and IGFBP3 on circulating IGF levels does not appear to substantially influence breast cancer risk substantially among primarily Caucasian postmenopausal women

    Collaborative Learning of Ontology Fragments by Cooperating Agents

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    Collaborating agents require either prior agreement on the shared vocabularies that they use for communication, or some means of translating between their private ontologies. Thus, techniques that enable agents to build shared vocabularies allow them to share and learn new concepts, and are therefore beneficial when these concepts are required on multiple occasions. However, if this is not carried out in an effective manner then the performance of an agent may be adversely affected by the time required to infer over large augmented ontologies, so causing problems in time-critical scenarios such as search and rescue. In this paper, we present a new technique that enables agents to augment their ontology with carefully selected concepts into their ontology. We contextualise this generic approach in the domain of RoboCup Rescue. Specifically, we show, through empirical evaluation, that our approach saves more civilians, reduces the percentage of the city burnt, and spends the least amount of time accessing its ontology compared with other state of the art benchmark approaches
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