66 research outputs found
In vivo laser Doppler holography of the human retina
The eye offers a unique opportunity for non-invasive exploration of
cardiovascular diseases. Optical angiography in the retina requires sensitive
measurements, which hinders conventional full-field laser Doppler imaging
schemes. To overcome this limitation, we used digital holography to perform
laser Doppler perfusion imaging of the human retina in vivo with near-infrared
light. Wideband measurements of the beat frequency spectrum of optical
interferograms recorded with a 39 kHz CMOS camera are analyzed by short-time
Fourier transformation. Power Doppler images and movies drawn from the zeroth
moment of the power spectrum density reveal blood flows in retinal and
choroidal vessels over 512 512 pixels covering 2.4 2.4 mm
on the retina with a 13 ms temporal resolution.Comment: 5 pages, 5 figure
Pulsatile microvascular blood flow imaging by short-time Fourier transform analysis of ultrafast laser holographic interferometry
We report on wide-field imaging of pulsatile microvascular blood flow in the
exposed cerebral cortex of a mouse by holographic interferometry. We recorded
interferograms of laser light backscattered by the tissue, beating against an
off-axis reference beam with a 50 kHz framerate camera. Videos of local Doppler
contrasts were rendered numerically by Fresnel transformation and short-time
Fourier transform analysis. This approach enabled instantaneous imaging of
pulsatile blood flow contrasts in superficial blood vessels over 256 x 256
pixels with a spatial resolution of 10 microns and a temporal resolution of 20
ms.Comment: 4 page
Extended resections for bronchogenic carcinoma invading the superior vena cava system
Extended resection of non-small-cell lung cancer (NSCLC) involving the superior vena cava (SVC) system is infrequently performed and oncologic benefits are still uncertain
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