Evidence for the classical integrability of the complete AdS(4) x CP(3) superstring

We construct a zero-curvature Lax connection in a sub-sector of the superstring theory on AdS(4) x CP(3) which is not described by the OSp(6|4)/U(3) x SO(1,3) supercoset sigma-model. In this sub-sector worldsheet fermions associated to eight broken supersymmetries of the type IIA background are physical fields. As such, the prescription for the construction of the Lax connection based on the Z_4-automorphism of the isometry superalgebra OSp(6|4) does not do the job. So, to construct the Lax connection we have used an alternative method which nevertheless relies on the isometry of the target superspace and kappa-symmetry of the Green-Schwarz superstring.Comment: 1+26 pages; v2: minor typos corrected, acknowledgements adde

More on integrable structures of superstrings in AdS(4) x CP(3) and AdS(2) x S(2) x T(6) superbackgrounds

In this paper we continue the study, initiated in arXiv:1009.3498 and arXiv:1104.1793, of the classical integrability of Green-Schwarz superstrings in AdS(4) x CP(3) and AdS(2) x S(2) x T(6) superbackgrounds whose spectrum contains non-supercoset worldsheet degrees of freedom corresponding to broken supersymmetries in the bulk. We derive an explicit expression, to all orders in the coset fermions and to second order in the non-coset fermions, which extends the supercoset Lax connection in these backgrounds with terms depending on the non-coset fermions. An important property of the obtained form of the Lax connection is that it is invariant under Z_4-transformations of the superisometry generators and the spectral parameter. This demonstrates that the contribution of the non-coset fermions does not spoil the Z_4-symmetry of the super-coset Lax connection which is of crucial importance for the application of Bethe-ansatz techniques. The expressions describing the AdS(4) x CP(3) and AdS(2) x S(2) x T(6) superstring sigma--models and their Lax connections have a very similar form. This is because their amount of target-space supersymmetries complement each other to 32=24+8, the maximal number of 10d type II supersymmetries. As a byproduct, this similarity has allowed us to obtain the form of the geometry of the complete type IIA AdS(2) x S(2) x T(6) superspace to all orders in the coset fermions and to the second order in the non-coset ones.Comment: 28 pages; v2: References adde

Apical Transport of Influenza A Virus Ribonucleoprotein Requires Rab11-positive Recycling Endosome

Influenza A virus RNA genome exists as eight-segmented ribonucleoprotein complexes containing viral RNA polymerase and nucleoprotein (vRNPs). Packaging of vRNPs and virus budding take place at the apical plasma membrane (APM). However, little is known about the molecular mechanisms of apical transport of newly synthesized vRNP. Transfection of fluorescent-labeled antibody and subsequent live cell imaging revealed that punctate vRNP signals moved along microtubules rapidly but intermittently in both directions, suggestive of vesicle trafficking. Using a series of Rab family protein, we demonstrated that progeny vRNP localized to recycling endosome (RE) in an active/GTP-bound Rab11-dependent manner. The vRNP interacted with Rab11 through viral RNA polymerase. The localization of vRNP to RE and subsequent accumulation to the APM were impaired by overexpression of Rab binding domains (RBD) of Rab11 family interacting proteins (Rab11-FIPs). Similarly, no APM accumulation was observed by overexpression of class II Rab11-FIP mutants lacking RBD. These results suggest that the progeny vRNP makes use of Rab11-dependent RE machinery for APM trafficking