46 research outputs found
Mobile Jacobi schemes for parallel computation
AbstractParallel computers (such as the distributed array professor and systolic arrays) bring into consideration the Jacobi method where several non-interacting rotations can be performed simultaneously. However, the design of the algorithm is much more crucial in a parallel environment; inefficiencies can lead to considerable organizationa costs. This paper provides a general framework for the description of mobile schemes together with two specific schemes, the better of which reduces the organizational overheads for the jacobi method to zero
Computation of normal form coefficients of cycle bifurcations of maps by algorithmic differentiation
Aspects of electrostatics in a weak gravitational field
Several features of electrostatics of point charged particles in a weak,
homogeneous, gravitational field are discussed using the Rindler metric to
model the gravitational field. Some previously known results are obtained by
simpler and more transparent procedures and are interpreted in an intuitive
manner. Specifically: (i) We show that the electrostatic potential of a charge
at rest in the Rindler frame is expressible as A_0=(q/l) where l is the affine
parameter distance along the null geodesic from the charge to the field point.
(ii) We obtain the sum of the electrostatic forces exerted by one charge on
another in the Rindler frame and discuss its interpretation. (iii) We show how
a purely electrostatic term in the Rindler frame appears as a radiation term in
the inertial frame. (In part, this arises because charges at rest in a weak
gravitational field possess additional weight due to their electrostatic
energy. This weight is proportional to the acceleration and falls inversely
with distance -- which are the usual characteristics of a radiation field.)
(iv) We also interpret the origin of the radiation reaction term by extending
our approach to include a slowly varying acceleration. Many of these results
might have possible extensions for the case of electrostatics in an arbitrary
static geometry. [Abridged Abstract]Comment: 26 pages; accepted for publication in Gen.Rel.Gra
Zitterbewegung in External Magnetic Field: Classic versus Quantum Approach
We investigate variations of the Zitterbewegung frequency of electron due to
an external static and uniform magnetic field employing the expectation value
quantum approach, and compare our results with the classical model of spinning
particles. We demonstrate that these two so far compatible approaches are not
in agreement in the presence of an external uniform static magnetic field, in
which the classical approach breaks the usual symmetry of free particles and
antiparticles states, i.e. it leads to CP violation. Hence, regarding the
Zitterbewegung frequency of electron, the classical approach in the presence of
an external magnetic field is unlikely to correctly describe the spin of
electron, while the quantum approach does, as expected. We also show that the
results obtained via the expectation value are in close agreement with the
quantum approach of the Heisenberg picture derived in the literature. However,
the method we use is capable of being compared with the classical approach
regarding the spin aspects. The classical interpretation of spin produced by
the altered Zitterbewegung frequency, in the presence of an external magnetic
field, are discussed.Comment: 16 pages, no figure
Biomarkers of Multiple Sclerosis
The search for an ideal multiple sclerosis biomarker with good diagnostic value, prognostic reference and an impact on clinical outcome has yet to be realized and is still ongoing. The aim of this review is to establish an overview of the frequent biomarkers for multiple sclerosis that exist to date. The review summarizes the results obtained from electronic databases, as well as thorough manual searches. In this review the sources and methods of biomarkers extraction are described; in addition to the description of each biomarker, determination of the prognostic, diagnostic, disease monitoring and treatment response values besides clinical impact they might possess. We divided the biomarkers into three categories according to the achievement method: laboratory markers, genetic-immunogenetic markers and imaging markers. We have found two biomarkers at the time being considered the gold standard for MS diagnostics. Unfortunately, there does not exist a single solitary marker being able to present reliable diagnostic value, prognostic value, high sensitivity and specificity as well as clinical impact. We need more studies to find the best biomarker for MS.publishersversionPeer reviewe
Lactacidemia e concentrações séricas de aspartato aminotransferase e creatinoquinase em equinos da raça Quarto de Milha usados em provas de laço em dupla
O presente estudo teve por objetivo avaliar a influência do exercício físico de alta intensidade e curta duração (provas de laço em dupla) sobre a lactacidemia e as concentrações séricas de aspartato aminotransferase (AST) e creatinoquinase (CK) em equinos durante competição realizada no estado do Espírito Santo. Para tal foram obtidas amostras de soro e plasma de 20 equinos, da raça Quarto de Milha ou mestiços, em três momentos assim definidos: no repouso, uma semana antes da prova atlética, já com o animal em treinamento (T0); antes da prova atlética (T1) e imediatamente após o término da mesma (T2). As referidas amostras foram encaminhadas ao Laboratório Clínico do Centro Universitário Vila Velha (UVV) para as análises. Na avaliação da lactacidemia, os resultados registrados nos momentos T0, T1 e T2 foram, respectivamente, de 0,49±0,24mmol/L, 0,93±0,16mmol/L e 9,86±2,09mmol/L. Na avaliação da atividade sérica de AST, os resultados registrados nos momentos T0, T1e T2 foram, respectivamente, de 189,1±43,6 UI/L, 210,2±46,7 UI/L e 173,1±33,5 UI/L. Por fim, a avaliação da atividade sérica da CK nos momentos T0,T1 e T2 foram,respectivamente, de 110,9±35,2 UI/L, 51,8±15,4 UI/L e 88,2±33,5 UI/L. A análise dos resultados demonstrou que o exercício físico imposto levou ao aumento significativo de lactato plasmático e CK sérica e não alterou o AST sérico e que a interpretação destes resultados permitiu concluir que os equinos usados estavam aptos ao nível de exercício físico imposto
Prevalence and Risk Factors of Neurologic Manifestations in Hospitalized Children Diagnosed with Acute SARS-CoV-2 or MIS-C
Background: Our objective was to characterize the frequency, early impact, and risk factors for neurological manifestations in hospitalized children with acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or multisystem inflammatory syndrome in children (MIS-C). Methods: Multicenter, cross-sectional study of neurological manifestations in children aged <18 years hospitalized with positive SARS-CoV-2 test or clinical diagnosis of a SARS-CoV-2-related condition between January 2020 and April 2021. Multivariable logistic regression to identify risk factors for neurological manifestations was performed. Results: Of 1493 children, 1278 (86%) were diagnosed with acute SARS-CoV-2 and 215 (14%) with MIS-C. Overall, 44% of the cohort (40% acute SARS-CoV-2 and 66% MIS-C) had at least one neurological manifestation. The most common neurological findings in children with acute SARS-CoV-2 and MIS-C diagnosis were headache (16% and 47%) and acute encephalopathy (15% and 22%), both P < 0.05. Children with neurological manifestations were more likely to require intensive care unit (ICU) care (51% vs 22%), P < 0.001. In multivariable logistic regression, children with neurological manifestations were older (odds ratio [OR] 1.1 and 95% confidence interval [CI] 1.07 to 1.13) and more likely to have MIS-C versus acute SARS-CoV-2 (OR 2.16, 95% CI 1.45 to 3.24), pre-existing neurological and metabolic conditions (OR 3.48, 95% CI 2.37 to 5.15; and OR 1.65, 95% CI 1.04 to 2.66, respectively), and pharyngeal (OR 1.74, 95% CI 1.16 to 2.64) or abdominal pain (OR 1.43, 95% CI 1.03 to 2.00); all P < 0.05. Conclusions: In this multicenter study, 44% of children hospitalized with SARS-CoV-2-related conditions experienced neurological manifestations, which were associated with ICU admission and pre-existing neurological condition. Posthospital assessment for, and support of, functional impairment and neuroprotective strategies are vitally needed