69 research outputs found
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Electrochemical Tailoring of Honeycomb-Structured ZnO Thin Films by Interfacial Surfactant Templating
Zinc oxide thin films with honeycomb structures can be electrochemically produced by interfacial surfactant templating. Newly synthesized 4-amino-1-(2,3-dihydroxy propyl) pyridinium hydroxide ionic liquid exhibiting the hydroxyl functionalized ionic liquids (HFILs) was used in electrodeposition. This method utilizes amphiphile assemblies at the solid-liquid interface (i.e., the surface of a working electrode) as a template to gain the precisely tailor zinc oxide nanostructures. The results described here will provide a useful foundation to design and optimize greener protocol for the electrochemical construction of inorganic nanostructures thin films for possible application of films in nanotechnology field. Moreover, it is believed that this electrochemical tailoring approach can be extended to fabricate other porous metal oxide materials with a unique morphology or shape.Peer Reviewe
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Self-assembly and anti-amyloid cytotoxicity activity of amyloid beta peptide derivatives
The self-assembly of two derivatives of KLVFF, a fragment Abeta(16-20) of the amyloid beta (Abeta) peptide, is investigated and recovery of viability of neuroblastoma cells exposed to Abeta is observed at sub-stoichiometric peptide concentrations. Fluorescence assays show that NH2-KLVFF-CONH2 undergoes hydrophobic collapse and amyloid formation at the same critical aggregation concentration (cac). In contrast, NH2-K(Boc)LVFF-CONH2 undergoes hydrophobic collapse at a low concentration, followed by amyloid formation at a higher cac. These findings are supported by the beta-sheet features observed by FTIR. Electrospray ionization mass spectrometry indicates that NH2-K(Boc)LVFF-CONH2 forms a significant population of oligomeric species above the cac. Cryo-TEM, used together with SAXS to determine fibril dimensions, shows that the length and degree of twisting of peptide fibrils seem to be influenced by the net peptide charge. Grazing incidence X-ray scattering from thin peptide films shows features of beta-sheet ordering for both peptides, along with evidence for lamellar ordering of NH2-KLVFF-CONH2. This work provides a comprehensive picture of the aggregation properties of these two KLVFF derivatives and show their utility, in unaggregated form, in restoring the viability of neuroblastoma cells against Abeta-induced toxicity
Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer
Efficacy of Major Plant Extracts/Molecules on Field Insect Pests
Insect pests are considered the major hurdle in enhancing the production and productivity of any farming system. The use of conventional synthetic pesticides has led to the emergence of pesticide-resistant insects, environmental pollution, and negative effects on natural enemies, which have caused an ecological imbalance of the predator-prey ratio and human health hazards; therefore, eco-friendly alternative strategies are required. The plant kingdom, a rich repertoire of secondary metabolites, can be tapped as an alternative for insect pest management strategies. A number of plants have been documented to have insecticidal properties against various orders of insects in vitro by acting as antifeedants, repellents, sterilant and oviposition deterrents, etc. However, only a few plant compounds are applicable at the field level or presently commercialised. Here, we have provided an overview of the broad-spectrum insecticidal activity of plant compounds from neem, Annona, Pongamia, and Jatropha. Additionally, the impact of medicinal plants, herbs, spices, and essential oils has been reviewed briefl
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Not AvailableShoot fly is one of the major pests of sorghum in India, which causes substantial economic losses in sorghum production. Levels of host plant resistance to sorghum shoot fly is low to moderate. Mutagenesis is a potential tool to induce new variation for crop improvement. Seeds of sorghum genotype IS 18551, a shoot fly resistant line, were mutated by irradiating with 500 Gy gamma rays. These mutants were evaluated under field condition for two seasons at four locations for resistance to shoot fly. Finally 30 mutant lines showed resistance to shoot fly across three hot spot locations over the resistance check (IS 18551) and three mutant lines showed break down of resistance and was on par with susceptible check (DJ 6514) were identified. Genetic analyses of these lines would throw light on the genes underlying resistance/susceptibility and facilitate development of genotypes with enhanced resistance.Not Availabl
Effective atomic numbers in some food materials and medicines for γ -ray attenuation using 137 Cs γ -ray
Simultaneous LC Estimation of Glimepiride and Metformin in Glimepiride Immediate Release and Metformin Sustained Release Tablets
A carbon monoxide interdigitated-capacitor gas sensor based upon a n-type Zn2SnO4 thin film
Synthesis of WS2 and WSe2 nanowires on stainless steel coupon by reaction under autogenic pressure at elevated temperature method
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