Early lesions in lymphoid neoplasia

The increasing use of immunophenotypic and molecular techniques on lymphoid tissue samples without obvious involvement by malignant lymphoma has resulted in the increased detection of “early” lymphoid proliferations, which show some, but not all the criteria necessary for a diagnosis of malignant lymphoma. In most instances, these are incidental findings in asymptomatic individuals, and their biological behaviour is uncertain. In order to better characterize these premalignant conditions and to establish diagnostic criteria, a joint workshop of the European Association for Haematopathology and the Society of Hematopathology was held in Uppsala, Sweden, in September 2010. The panel reviewed and discussed more than 130 submitted cases and reached consensus diagnoses. Cases representing the nodal equivalent of monoclonal B-cell lymphocytosis (MBL) were discussed, as well as the “in situ” counterparts of follicular lymphoma (FL) and mantle cell lymphoma (MCL), topics that also stimulated discussions concerning the best terminology for these lesions. The workshop also addressed the borderland between reactive hyperplasia, and clonal proliferations such as pediatric marginal zone lymphoma and pediatric FL, which may have very limited capacity for progression. Virus-driven lymphoproliferations in the grey zone between reactive lesions and manifest malignant lymphoma were covered. Finally, early manifestations of T-cell lymphoma, both nodal and extranodal, and their mimics were addressed. This workshop report summarizes the most important conclusions concerning diagnostic features, as well as proposals for terminology and classification of early lymphoproliferations and tries to give some practical guidelines for diagnosis and reporting

No-reference image and video quality assessment: a classification and review of recent approaches

The field of perceptual quality assessment has gone through a wide range of developments and it is still growing. In particular, the area of no-reference (NR) image and video quality assessment has progressed rapidly during the last decade. In this article, we present a classification and review of latest published research work in the area of NR image and video quality assessment. The NR methods of visual quality assessment considered for review are structured into categories and subcategories based on the types of methodologies used for the underlying processing employed for quality estimation. Overall, the classification has been done into three categories, namely, pixel-based methods, bitstream-based methods, and hybrid methods of the aforementioned two categories. We believe that the review presented in this article will be helpful for practitioners as well as for researchers to keep abreast of the recent developments in the area of NR image and video quality assessment. This article can be used for various purposes such as gaining a structured overview of the field and to carry out performance comparisons for the state-of-the-art methods