4,673 research outputs found

    Assessment of oil contamination in the bay of Porto Grande (Cape Verde) using the mullet Chelon bispinosus

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    Polycyclic aromatic hydrocarbons (PAHs) are a group of persistent organic pollutants, some of which are mutagenic and carcinogenic so PAH concentrations in fish used for human consumption are crucial to assess impact to human health. Total PAH concentrations in muscle and liver of mullets Chelon bispinosus from the Bay of Porto Grande (Cape Verde) (four sites in the bay and a control) ranged from 112.7 to 779.5 and 291.5 to 7548.7 ng/g d. w., respectively. Two and three ring PAHs were the most frequent (72.8 to 90.8% in the muscle and 75.9 to 98.3% in the liver), but levels of carcinogenic PAHs (mainly Dibenzo (a,h) antracene) in certain sites (CN and PG) are of concern. Results reflect a chronic PAH pollution in the bay and sources are a mixture of anthropogenic (petrogenic and pyrolytic) and natural sources, making their identification extremely complex. Although, BaP levels were below the threshold established by Cape Verde and the European Union, BaPEs levels in muscle ranged from 0.28 to 3.66 ng/g w. w. and BAPEs and TPAHs exposure for the average adult was 0.02 to 0.26 and 1.6 to 11.2 μg/day, respectively. Further knowledge of PAH concentrations in other species are necessary for a proper environmental risk assessment policy.Key words: Bay of Porto Grande, Cape Verde, Chelon bispinosus, mullets, PAHs, BaPEs, daily intake

    Management of Iatrogenic Urorectal Fistulae in Men with Pelvic Cancer

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    INTRODUCTION: Urorectal fistula (URF) is a devastating complication of pelvic cancer treatments and a surgical challenge for the reconstructive surgeon. We report a series of male patients with URF resulting from pelvic cancer treatments, specifically prostate (PCa), bladder (BCa), and rectal cancer (RCa), and explore the differences and impact on outcomes between purely surgical and non-surgical treatment modalities. METHODS: Between October 2008 and June 2015, 15 male patients, aged 59-78 years (mean 67), with URF induced by pelvic cancer treatments were identified in our institutions. Patients with a history of diverticulitis, inflammatory bowel disease, or other benign conditions were excluded. We reviewed the patients' medical records for symptoms, diagnostic tests performed, type and etiology of the fistula, type of surgical reconstruction, followup, and outcomes. RESULTS: Fourteen patients underwent surgical reconstruction. One patient developed metastatic disease before URF repair and, therefore, was excluded from this study. Mean followup (FU) was 32.7 months (14-79). All patients received diverting colostomy and temporary urinary diversion. An exclusively transperineal approach was used in nine (64.3%) patients and a combined abdominoperineal in five (35.7%). Overall successful URF closure was achieved in 12 (85.7%) patients, nine (64.3%) of whom at the first reconstructive attempt, two (14.3%) after two attempts (in our institution), and one (7.1%) after three attempts (two of which elsewhere). An interposition flap was used in seven (50%) patients. Surgical reconstruction failed ultimately in two (14.3%) patients who still have a colostomy and do not wish any further reconstruction. CONCLUSIONS: Our study has several limitations, including its retrospective nature and the heterogeneity of our small patient cohort. Nonetheless, although surgical reconstruction of URF may be extremely difficult and complex in the non-surgical/energy ablation patients, its successful reconstruction is possible in most through a transperineal, or a more aggressive abdominoperineal, approach with tissue interposition in selected patients.info:eu-repo/semantics/publishedVersio

    Estudo preliminar aos níveis de eliminação em ovinos das raças merina branca e merina preta por estrongilídeos gastrointestinais .

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    As raças Merina Branca e Merina Preta apresentam um potencial de produção de carne assinalável, aliado a características de rusticidade, longevidade e resistência a doenças. Animais explorados em regimes extensivos, muitas vezes associados ao ecossistema montado, poderão ter um papel importante no âmbito dos novos modos de produção sustentada (Programa de conservação / Melhoramento Genético, 2007). As estrongiloses nos ovinos são responsáveis por importantes perdas económicas ao nível dos sistemas de produção. Estas perdas reflectem as alterações dos índices produtivos e reprodutivos, assim como no bem-estar e saúde animal. No controlo das estrongiloses gastrointestinais é necessário uma abordagem integrada que contribua para uma produção animal sustentável. Foi objectivo avaliar os níveis de eliminação de ovos/g de EGI (OPG) em ovinos das raças Merina Branca e Merina Preta e determinar a abundancia proporcional média dos diferentes géneros presentes. Procedeu-se à colheita de amostras coprológicas individuais directamente da ampola rectal a 40 fêmeas jovens e a 40 fêmeas adultas. Foram determinados os níveis de eliminação de OPG através da técnica modificada de Mackmaster (Hammond & Sewel, 1978). A abundancia proporcional média foi calculada após estudo morfométrico das L3 obtidas em coprocultura. No tratamento dos dados recorreu-se à análise de variância e análise descritiva. Nos níveis de eliminação de OPG verificaram-se diferenças significativas entre raças. Nas fêmeas jovens os valores obtidos revelaram uma diferença altamente significativa (p <0,01) entre as raças. Nas fêmeas adultas as diferenças verificadas foram apenas significativas (p <0,05). Após obtenção das L3 em coprocultura, foram identificados 3 géneros de EGI: Trichostrongylus sp.; Teledorsagia sp. e Oesophagostomum sp.. Na determinação da abundancia proporcional média dos géneros presentes, observou-se que a Teledorsagia sp. foi o género mais abundante nas fêmeas jovens enquanto que, Trichostriongylus sp. revelou-se como o mais abundante nas fêmeas adultas. Os resultados obtidos parecem expressar uma diferente capacidade de resistência à infecção por EGI nas duas raças. Sendo a resistência aos EGI um processo multifactorial, deverão ter-se em consideração factores não abordados neste estudo
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