O mercado da tilápia - 2° trimestre de 2017 e análise da estrutura do preço da tilápia no varejo.

Este trabalho pretende auxiliar na compreensão da evolução do mercado da tilápia por meio da análise dos preços de varejo e estudos relativos.bitstream/item/162159/1/CNPASA-2017-mt11.pdfEdição especial

The São Paulo wholesale seafood market: A study of fish prices in Brazil.

We analyze fish pricing in the São Paulo wholesale market, the second largest seafood market in South America. Quantitative price analysis is complemented by interviews with participants in the value chain to answer how the multitude of fish products supplied in this market are related and the challenges facing future growth. The results reveal a clear separate pricing of domestically produced fishery species (whitefish and pelagics) from the internationally traded aquaculture species (tilapia and salmon). Tilapia and salmon are uniquely priced, less volatile and more persistent with a price dynamic more akin to local terrestrial meats. Fishery prices show large month-by-month fluctuations and compete more with each other. Participants in the different levels of the value chain corroborate the uniqueness of salmon and state a preference for stable availability and low prices, with less concern about the specific sourcing of fish (aquaculture/fisher, or domestic/imported)

Genetic polymorphisms in DNA mismatch repair-related genes predict outcome in patients with head and neck squamous cell carcinoma treated with cisplatin and radiotherapy

Cisplatin (CDDP) associated with radiotherapy (RT) has been used in treatment of patients with head and neck squamous cell carcinoma (HNSCC) with distinct results among those with similar clinicopathological aspects. The aim of this study was to access wh276sem informaçãosem informaçã

GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms in outcomes of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation

Cisplatin (CDDP) combined with radiotherapy (RT) is employed in head and neck squamous cell carcinoma (HNSCC) with variable toxicities and clinical response. Glutathione S-transferases (GSTs) participate in CDDP excretion from cells, and genes encoding GSTs, GSTM1, GSTT1and GSTP1, are polymorphic in humans. This prospective study aimed to evaluate the roles of GSTM1, GSTT1, and GSTP1 ille105Val polymorphisms in outcomes of HNSCC patients treated with CDDP chemoradiation. Ninety patients were genotyped by multiplex PCR. Urinary CDDP measurements were performed by HPLC. Treatment side effects and response were analysed by conventional criteria. Patients with GSTT1 genes showed 7.23- and 5.37-fold higher likelihood of presenting vomiting and ototoxicity, lower glomerular filtration rate (GFR), and lower elimination of CDDP in urine relative to patients with deleted genes. Patients harbouring the GSTP1 IleVal orValVal genotypes showed 4.28-fold higher likelihood of presenting grade 2 or 3 vomiting and lower GFR with treatment than those harbouring the Ilelle genotype. In multivariate Cox analysis, patients with the GSTP/1 105ValVal genotype had 3.87 more chance of presenting disease progression than those with the Ilelle or IleVal genotype (p < 0.01). Our findings provide preliminary evidence that inherited abnormalities in CDDP metabolism, related to GSTT1 and GSTP/1 ille105Val polymorphisms, alter outcomes of HNSCC patients treated with CDDP and RT9FAPESP – Fundação de Amparo à Pesquisa Do Estado De São Paulo2012/1807-