Myopalladin promotes muscle growth through modulation of the serum response factor pathway

Myopalladin (MYPN) is a striated muscle-specific, immunoglobulin-containing protein located in the Z-line and I-band of the sarcomere as well as the nucleus. Heterozygous MYPN gene mutations are associated with hypertrophic, dilated, and restrictive cardiomyopathy, and homozygous loss-of-function truncating mutations have recently been identified in patients with cap myopathy, nemaline myopathy, and congenital myopathy with hanging big toe

Il rapporto tra Corte costituzionale e autorità giudiziaria nel controllo sulle leggi in Italia: 50 anni di giurisprudenza costituzionale

L'articolo, collocato nell'ambito di un volume sulle principali esperienze europee, esamina i rapporti tra Corte cost. e autorità giudiziaria, da un punto di vista di sistema e nella concreta applicazione,anche alla luce dell'accresciuto ruolo delle giurisdizioni sovranazional

Synthesis and X-ray crystallographic structures of dichloronickel(II) and -palladium(II) complexes containing the biphenyl diamine ligand 6-(2-dimethylaminoethyl)-6,7-dihydro-5-H-dibenz[c,e]azepin

The diamine N N (N N = 6-(2-dimethylaminoethyl)-6,7-dihydro-5-H-dibenz[c,e]azepin (1)) has been prepared and characterised. It reacts with nickel(II) chloride and bis(benzonitrile)dichloropalladium giving the corresponding complexes MCl2(N N) (M = Ni, 6; Pd, 7) whose crystal structures have been determined. The nickel coordination in complex 6 is distorted tetrahedral, whereas the palladium coordination in complex 7 is square planar. (C) 1999 Elsevier Science S.A. All rights reserved