Nigrospora sp. in post-harvest papayas: efficacy of essential oils in antifungal inhibition

Climate change is negatively impacting ecosystems and encouraging the spread of new post-harvest diseases. This research evaluated two essential oils (EOs) as alternatives for controlling emerging fungal diseases. In vitro and in vivo studies were conducted with clove (Syzygium aromaticum) EO (CEO) and oregano (Origanum vulgare) EO (OEO) against the fungus Nigrospora sp. Both EOs were tested in vitro at concentrations of 62.5−1,000 μL·L−1. In vivo tests on papayas fruits belonging to the Solo group used in curative and preventive applications. Weight loss, fruit length, diameter, and skin color were evaluated over eight days. The Minimum Inhibitory Concentration (MIC) was 125−250 μL·L−1 for both EOs. Clove EO was more effective curatively, while oregano EO was more effective preventively. Papayas fruits treated with EOs lost less weight (9% for CEO and 8% for OEO) compared to controls (16%). Treated fruits maintained the length and diameter. Clove and oregano EOs offer a sustainable alternative to synthetic fungicides for post-harvest fruit preservation

Anteroventral third ventricle (AV3V) lesions impair cardiovascular responses to intravenous hypertonic saline (HT) infusion

Univ Fed São Paulo, Escola Paulista Med, Dept Physiol, BR-04023060 São Paulo, BrazilPaulista State Univ, Sch Dent, Dept Physiol & Pathol, BR-14801903 Araraquara, SP, BrazilPaulista State Univ, Sch Dent, Dept Physiol & Pathol, BR-14801903 Araraquara, SP, Brazi

Role of A1 noradrenergic neurons in cardiovascular responses induced by acute changes in circulating volume

UNIFESP, EPM, BR-04023060 São Paulo, BrazilUNESP, BR-14801380 Araraquara, BrazilUNESP, BR-14801380 Araraquara, Brazi