8,311 research outputs found
Realising Intentions: An evaluation of green building rating tools for Australian buildings
With growing concerns for enhancing sustainability, much attention has being paid to benchmarking performance in buildings. This paper evaluates the effectiveness of three rating systems that have been widely adopted for over a decade in Australia namely: (i) mandatory compliance under Section J (Energy Efficiency provisions) in the National Construction Code of Australia (NCC), (ii) a voluntary design rating tool - Green Star, and (iii) a voluntary operational rating tool-National Australian Building Environmental Rating Scheme (NABERS). The paper builds on the authorsâ experience in building performance simulation, rating tool design, practice consultancy and post occupancy evaluations of buildings. It presents a detailed analysis of the rating tools with respect to the alignment between what is being assessed, how it is assessed and administered and the impact on design process and performance outcomes in buildings. The paper assesses the successes and shortcomings of the rating tools to demonstrate the potential for design and post occupancy rating tools to influence market behaviour and building performance and argues for increasingly stringent approaches to get to net zero emissions
Effective natural ventilation in modern apartment buildings
This paper addresses the challenge of evaluating for natural ventilation in modern apartment buildings. A number of natural ventilation design rules of thumb from published literature are listed. Their incorporation into one code for Australia (the Residential Flat Design Code, or RFDC) and India (the National Building Code, or NBC), in relation to apartment buildings is examined. Practical limitations to converting these rules of thumb into effective natural ventilation systems for apartment building designs are discussed. Apartment designs in the moderate locations of Sydney, Australia and Bengaluru, India are also reviewed to assess their effectiveness for natural ventilation. Simulation analysis presented indicate large energy savings are possible if apartments are retrofitted/designed to the proposed code requirements and designs compliant with thumb rules are capable of delivering effective natural ventilation if users choose to operate the apartment in âfree running modeâ during times when the outside dry bulb temperatures lie in an appropriate band. The paper also discusses how sub-optimal design solutions, affluence and adaptation to more stringent thermal conditions can negate the potential for natural ventilation and calls for proactive efforts to maintain climate responsive design standards and education/policy to encourage the benefits of natural ventilation over airconditioning
A Characterization of Mixed Unit Interval Graphs
We give a complete characterization of mixed unit interval graphs, the
intersection graphs of closed, open, and half-open unit intervals of the real
line. This is a proper superclass of the well known unit interval graphs. Our
result solves a problem posed by Dourado, Le, Protti, Rautenbach and
Szwarcfiter (Mixed unit interval graphs, Discrete Math. 312, 3357-3363 (2012)).Comment: 17 pages, referees' comments adde
The transcriptome of the novel dinoflagellate Oxyrrhis marina (Alveolata: Dinophyceae): response to salinity examined by 454 sequencing
This is the final version of the article. Available from [BioMed Central via the DOI in this record.BACKGROUND: The heterotrophic dinoflagellate Oxyrrhis marina is increasingly studied in experimental, ecological and evolutionary contexts. Its basal phylogenetic position within the dinoflagellates make O. marina useful for understanding the origin of numerous unusual features of the dinoflagellate lineage; its broad distribution has lent O. marina to the study of protist biogeography; and nutritive flexibility and eurytopy have made it a common lab rat for the investigation of physiological responses of marine heterotrophic flagellates. Nevertheless, genome-scale resources for O. marina are scarce. Here we present a 454-based transcriptome survey for this organism. In addition, we assess sequence read abundance, as a proxy for gene expression, in response to salinity, an environmental factor potentially important in determining O. marina spatial distributions. RESULTS: Sequencing generated ~57 Mbp of data which assembled into 7, 398 contigs. Approximately 24% of contigs were nominally identified by BLAST. A further clustering of contigs (at â„ 90% identity) revealed 164 transcript variant clusters, the largest of which (Phosphoribosylaminoimidazole-succinocarboxamide synthase) was composed of 28 variants displaying predominately synonymous variation. In a genomic context, a sample of 5 different genes were demonstrated to occur as tandem repeats, separated by short (~200-340 bp) inter-genic regions. For HSP90 several intergenic variants were detected suggesting a potentially complex genomic arrangement. In response to salinity, analysis of 454 read abundance highlighted 9 and 20 genes over or under expressed at 50 PSU, respectively. However, 454 read abundance and subsequent qPCR validation did not correlate well - suggesting that measures of gene expression via ad hoc analysis of sequence read abundance require careful interpretation. CONCLUSION: Here we indicate that tandem gene arrangements and the occurrence of multiple transcribed gene variants are common and indicate potentially complex genomic arrangements in O. marina. Comparison of the reported data set with existing O. marina and other dinoflagellates ESTs indicates little sequence overlap likely as a result of the relatively limited extent of genome scale sequence data currently available for the dinoflagellates. This is one of the first 454-based transcriptome surveys of an ancestral dinoflagellate taxon and will undoubtedly prove useful for future comparative studies aimed at reconstructing the origin of novel features of the dinoflagellates.This work was supported by a NERC grant (NE/F005237/1) awarded to PCW, DJSM, and CDL. We would like to thank Dr Margret Hughes of the Liverpool CGR for conducting 454 sequencing, and Dr Kevin Ashelford for invaluable scripting and bioinformatics support
Digital Data Processing of Images
Digital data processing was investigated to perform image processing. Image smoothing and restoration were explored and promising results obtained. The use of the computer, not only as a data management device, but as an important tool to render quantitative information, was illustrated by lung function determination. The availability of on-line computers for image processing represents a major advance in the radiological investigation of organ function.S. Afr. Med. J., 48, 986 (1974)
The Statistical Mechanics of Horizons and Black Hole Thermodynamics
Although we know that black holes are characterized by a temperature and an
entropy, we do not yet have a satisfactory microscopic ``statistical
mechanical'' explanation for black hole thermodynamics. I describe a new
approach that attributes the thermodynamic properties to ``would-be gauge''
degrees of freedom that become dynamical on the horizon. For the
(2+1)-dimensional black hole, this approach gives the correct entropy. (Talk
given at the Pacific Conference on Gravitation and Cosmology, Seoul, February
1996.)Comment: 11 pages, LaTe
Multi-label and multimodal classifier for affectve states recognition in virtual rehabilitation
Computational systems that process multiple affective states may benefit from explicitly considering the interaction between
the states to enhance their recognition performance. This work proposes the combination of a multi-label classifier, Circular Classifier
Chain (CCC), with a multimodal classifier, Fusion using a Semi-Naive Bayesian classifier (FSNBC), to include explicitly the
dependencies between multiple affective states during the automatic recognition process. This combination of classifiers is applied to a
virtual rehabilitation context of post-stroke patients. We collected data from post-stroke patients, which include finger pressure, hand
movements, and facial expressions during ten longitudinal sessions. Videos of the sessions were labelled by clinicians to recognize
four states: tiredness, anxiety, pain, and engagement. Each state was modelled by the FSNBC receiving the information of finger
pressure, hand movements, and facial expressions. The four FSNBCs were linked in the CCC to exploit the dependency relationships
between the states. The convergence of CCC was reached by 5 iterations at most for all the patients. Results (ROC AUC) of CCC with
the FSNBC are over 0.940 ± 0.045 (mean ± std. deviation) for the four states. Relationships of mutual exclusion between engagement
and all the other states and co-occurrences between pain and anxiety were detected and discussed
Some algorithms to solve a bi-objectives problem for team selection
In real life, many problems are instances of combinatorial optimization. Cross-functional team selection is one of the typical issues. The decision-maker has to select solutions among (kh) solutions in the decision space, where k is the number of all candidates, and h is the number of members in the selected team. This paper is our continuing work since 2018; here, we introduce the completed version of the Min Distance to the Boundary model (MDSB) that allows access to both the "deep" and "wide" aspects of the selected team. The compromise programming approach enables decision-makers to ignore the parameters in the decision-making process. Instead, they point to the one scenario they expect. The aim of model construction focuses on finding the solution that matched the most to the expectation. We develop two algorithms: one is the genetic algorithm and another based on the philosophy of DC programming (DC) and its algorithm (DCA) to find the optimal solution. We also compared the introduced algorithms with the MIQP-CPLEX search algorithm to show their effectiveness
Validation and reproducibility of computerised cell-viability analysis of tissue slices
BACKGROUND: The identification of live cells using membrane integrity dyes has become a frequently used technique, especially with articular cartilage and chondrocytes in situ where tissue slices are used to assess cell recovery as a function of location. The development of a reproducible computerised method of cell evaluation would eliminate many variables associated with manual counting and significantly reduce the amount of time required to evaluate experimental results. METHODS: To validate a custom computerised counting program, intra-person and inter-person cell counts of nine human evaluators (three groups â unskilled, novice, and experienced) were compared with repeated pixel counts of the custom program on 15 digitised images (in triplicate) of chondrocytes in situ stained with fluorescent dyes. RESULTS: Results indicated increased reproducibility with increased experience within evaluators [Intraclass Correlation Coefficient (ICC) range = 0.67 (unskilled) to 0.99 (experienced)] and between evaluators [ICC = 0.47 (unskilled), 0.85 (novice), 0.93 (experienced)]. The computer program had perfect reproducibility (ICC = 1.0). There was a significant relationship between the average of the experienced evaluators results and the custom program results (ICC = 0.77). CONCLUSIONS: This study demonstrated that increased experience in cell counting resulted in increased reproducibility both within and between human evaluators but confirmed that the computer program was the most reproducible. There was a good correlation between the intact cell recovery determined by the computer program and the experienced human evaluators. The results of this study showed that the computer counting program was a reproducible tool to evaluate intact cell recovery after use of membrane integrity dyes on chondrocytes in situ. This and the significant decrease in the time used to count the cells by the computer program advocate its use in future studies because it has significant advantages
Is a soft tissue graft harvested from the maxillary tuberosity the approach of choice in an isolated site?
Soft tissue augmentation procedures are becoming more popular these days. Different soft tissue graft harvesting approaches have been proposed. Nonetheless, the location of the donor site (whether anterior-, lateral-, superficial-, deep-palate or the maxillary tuberosity) can affect the graft shape and its composition. Soft tissue grafts from the maxillary tuberosity are rich in connective tissue fibers, with minimal presence of fatty or glandular components. Clinical, histological, and molecular evidence shows that a soft tissue graft obtained from the maxillary tuberosity has unique properties. In addition, harvesting from this area presents minimal risk for intra- or postoperative complications, leading to reduced patient morbidity. The aim of this commentary is to discuss the advantages and disadvantages of harvesting a soft tissue graft from the tuberosity and to compare it with the traditional palatal graft, while highlighting functional, esthetic, and patient-related outcomes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151301/1/jper10300_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151301/2/jper10300.pd
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