724 research outputs found
Human Cytomegalovirus Glycoprotein UL16 Causes Intracellular Sequestration of NKG2D Ligands, Protecting Against Natural Killer Cell Cytotoxicity
The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I–related ligands, including the MIC and ULBP proteins. Infection, stress, or transformation can induce NKG2D ligand expression, resulting in effector cell activation and killing of the ligand-expressing target cell. The human cytomegalovirus (HCMV) membrane glycoprotein, UL16, binds to three of the five known ligands for human NKG2D. UL16 is retained in the endoplasmic reticulum and cis-Golgi apparatus of cells and causes MICB to be similarly retained and stabilized within cells. Coexpression of UL16 markedly reduces cell surface levels of MICB, ULBP1, and ULBP2, and decreases susceptibility to natural killer cell–mediated cytotoxicity. Domain swapping experiments demonstrate that the transmembrane and cytoplasmic domains of UL16 are important for intracellular retention of UL16, whereas the ectodomain of UL16 participates in down-regulation of NKG2D ligands. The intracellular sequestration of NKG2D ligands by UL16 represents a novel HCMV immune evasion mechanism to add to the well-documented viral strategies directed against antigen presentation by classical MHC molecules
Nodal Quasiparticle Dispersion in Strongly Correlated d-wave Superconductors
We analyze the effects of a momentum-dependent self-energy on the
photoemission momentum distribution curve (MDC) lineshape, dispersion and
linewidth. We illustrate this general analysis by a detailed examination of
nodal quasiparticles in high Tc cuprates. We use variational results for the
nodal quasiparticle weight Z (which varies rapidly with hole doping x) and the
low energy Fermi velocity (which is independent of x), to show that
the high energy MDC dispersion , so that it is much
larger than the bare (band structure) velocity and also increases strongly with
underdoping. We also present arguments for why the low energy Fermi velocity
and the high energy dispersion are independent of the bare band structure at
small x. All of these results are in good agreement with earlier and recent
photoemission data [Zhou et al, Nature 423, 398 (2003)].Comment: 4 pages, 3 eps fig
Unified description of ballistic and diffusive carrier transport in semiconductor structures
A unified theoretical description of ballistic and diffusive carrier
transport in parallel-plane semiconductor structures is developed within the
semiclassical model. The approach is based on the introduction of a
thermo-ballistic current consisting of carriers which move ballistically in the
electric field provided by the band edge potential, and are thermalized at
certain randomly distributed equilibration points by coupling to the background
of impurity atoms and carriers in equilibrium. The sum of the thermo-ballistic
and background currents is conserved, and is identified with the physical
current. The current-voltage characteristic for nondegenerate systems and the
zero-bias conductance for degenerate systems are expressed in terms of a
reduced resistance. For arbitrary mean free path and arbitrary shape of the
band edge potential profile, this quantity is determined from the solution of
an integral equation, which also provides the quasi-Fermi level and the
thermo-ballistic current. To illustrate the formalism, a number of simple
examples are considered explicitly. The present work is compared with previous
attempts towards a unified description of ballistic and diffusive transport.Comment: 23 pages, 10 figures, REVTEX
Lattice QCD Simulations in External Background Fields
We discuss recent results and future prospects regarding the investigation,
by lattice simulations, of the non-perturbative properties of QCD and of its
phase diagram in presence of magnetic or chromomagnetic background fields.
After a brief introduction to the formulation of lattice QCD in presence of
external fields, we focus on studies regarding the effects of external fields
on chiral symmetry breaking, on its restoration at finite temperature and on
deconfinement. We conclude with a few comments regarding the effects of
electromagnetic background fields on gluodynamics.Comment: 31 pages, 10 figures, minor changes and references added. To appear
in Lect. Notes Phys. "Strongly interacting matter in magnetic fields"
(Springer), edited by D. Kharzeev, K. Landsteiner, A. Schmitt, H.-U. Ye
Spin oscillations in transient diffusion of a spin pulse in n-type semiconductor quantum wells
By studying the time and spatial evolution of a pulse of the spin
polarization in -type semiconductor quantum wells, we highlight the
importance of the off-diagonal spin coherence in spin diffusion and transport.
Spin oscillations and spin polarization reverse along the the direction of spin
diffusion in the absence of the applied magnetic field are predicted from our
investigation.Comment: 5 pages, 4 figures, accepted for publication in PR
Multiplicity distributions at high energies as a sum of Poissonian-like distributions
It is shown that at collider energies experimental multiplicity distributions
are well parameterized by a sum of Gupta-Sarma distributions. This extends
earlier description of the lower energy data by the two parameter sum of
Poissonians. Implications of the proposed parametrization for LHC are
discussed.Comment: 16 pages, Latex, 4 EPS figure
Interplay of Electron-Phonon Interaction and Electron Correlation in High Temperature Superconductivity
We study the electron-phonon interaction in the strongly correlated
superconducting cuprates. Two types of the electron-phonon interactions are
introduced in the model; the diagonal and off-diagonal interactions which
modify the formation energy of the Zhang-Rice singlet and its transfer
integral, respectively. The characteristic phonon-momentum and
electron-momentum dependence resulted from the off-diagonal coupling
can explain a variety of experiments. The vertex correction for the
electron-phonon interaction is formulated in the SU(2) slave-boson theory by
taking into account the collective modes in the superconducting ground states.
It is shown that the vertex correction enhances the attractive potential for
the d-wave paring mediated by phonon with around
which corresponds to the half-breathing mode of the oxygen
motion.Comment: 14 pages, 13 figure
Mass-renormalized electronic excitations at (, 0) in the superconducting state of
Using high-resolution angle-resolved photoemission spectroscopy on
, we have made the first observation of a
mass renormalization or "kink" in the E vs. dispersion relation
localized near . Compared to the kink observed along the nodal
direction, this new effect is clearly stronger, appears at a lower energy near
40 meV, and is only present in the superconducting state. The kink energy scale
defines a cutoff below which well-defined quasiparticle excitations occur. This
effect is likely due to coupling to a bosonic excitation, with the most
plausible candidate being the magnetic resonance mode observed in inelastic
neutron scattering
An angle-resolved photoemission spectral function analysis of the electron doped cuprate Nd_1.85Ce_0.15CuO_4
Using methods made possible by recent advances in photoemission technology,
we perform an indepth line-shape analysis of the angle-resolved photoemission
spectra of the electron doped (n-type) cuprate superconductor
Nd_1.85Ce_0.15CuO_4. Unlike for the p-type materials, we only observe weak mass
renormalizations near 50-70 meV. This may be indicative of smaller
electron-phonon coupling or due to the masking effects of other interactions
that make the electron-phonon coupling harder to detect. This latter scenario
may suggest limitations of the spectral function analysis in extracting
electronic self-energies when some of the interactions are highly momentum
dependent.Comment: 8 pages, 5 figure
Horizontal Branch Stars: The Interplay between Observations and Theory, and Insights into the Formation of the Galaxy
We review HB stars in a broad astrophysical context, including both variable
and non-variable stars. A reassessment of the Oosterhoff dichotomy is
presented, which provides unprecedented detail regarding its origin and
systematics. We show that the Oosterhoff dichotomy and the distribution of
globular clusters (GCs) in the HB morphology-metallicity plane both exclude,
with high statistical significance, the possibility that the Galactic halo may
have formed from the accretion of dwarf galaxies resembling present-day Milky
Way satellites such as Fornax, Sagittarius, and the LMC. A rediscussion of the
second-parameter problem is presented. A technique is proposed to estimate the
HB types of extragalactic GCs on the basis of integrated far-UV photometry. The
relationship between the absolute V magnitude of the HB at the RR Lyrae level
and metallicity, as obtained on the basis of trigonometric parallax
measurements for the star RR Lyrae, is also revisited, giving a distance
modulus to the LMC of (m-M)_0 = 18.44+/-0.11. RR Lyrae period change rates are
studied. Finally, the conductive opacities used in evolutionary calculations of
low-mass stars are investigated. [ABRIDGED]Comment: 56 pages, 22 figures. Invited review, to appear in Astrophysics and
Space Scienc
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