Studies on the morphology of leukaemic blast cells in relation to haematological parameters

A combination of haematological parameters with morphological evaluation of peripheral blood and bone marrow blast cells is crucial for leukaemia diagnosis. FAB (French– American–British) classification is a simple and powerful diagnostic tool for leukaemia           in developing countries like India. Differentiation block in the early stages of haematopoiesis and morphological characteristics of leukemic blast cells are directly related to haematological parameters. The present study is an approach to increase understanding of the simple morphological FAB classification of leukaemia  in relation to haematological parameters. The present study revealed that Chronic Myeloid Leukaemia  (CML) was the most common type of leukaemia , followed by Acute Myeloid Leukaemia, Acute Lymphoid Leukaemia  (ALL), and Chronic Lymphoid Leukaemia  (CLL) in Nagpur. Most of the cases of Acute Leukaemia  had severe anaemia and thrombocytopenia. Highest variation was found in Total WBCs count of different types of leukaemia , particularly in different subtypes of AML. The present study also suggested that FAB classification is not outdated, but it does require continuous revalidation and other procedures for refinement.          &nbsp

Determining the position of artificial tooth in relation to the base of palatal rugae: a pilot study

The palatal rugae area is a prominent landmark in the maxillary arch and its position lie constant throughout the life and therefore it can be used as a guideline for the placement of artificial teeth in the maxillary arch. METHODS: 50 subjects were randomly selected and were evaluated for the position of the palatal rugae. RESULTS: 35 casts showed that the base of rugae lies on the distal margin of the 2nd premolar. 9 casts showed that the base of the rugae lies on distal half of the 2nd premolar.6 casts showed that base of the rugae lies on mesial half of the 2nd premolar. Conclusion : Thus in artificial teeth arrangement 2nd premolar can be place in relation to the base of the palatal rugae. This will also guide us in the selection of proper size and form of the artificial teeth set