1,714 research outputs found
Dimensional Crossover in the Effective Second Harmonic Generation of Films of Random Dielectrics
The effective nonlinear response of films of random composites consisting of
a binary composite with nonlinear particles randomly embedded in a linear host
is theoretically and numerically studied. A theoretical expression for the
effective second harmonic generation susceptibility, incorporating the
thickness of the film, is obtained by combining a modified effective-medium
approximation with the general expression for the effective second harmonic
generation susceptibility in a composite. The validity of the thoretical
results is tested against results obtained by numerical simulations on random
resistor networks. Numerical results are found to be well described by our
theory. The result implies that the effective-medium approximation provides a
convenient way for the estimation of the nonlinear response in films of random
dielectrics.Comment: 9 pages, 2 figures; accepted for publication in Phys. Rev.
Microheated substrates for patterning cells and controlling development
Here, we seek to control cellular development by devising a means through which cells can be subjected to a microheated environment in standard culture conditions. Numerous techniques have been devised for controlling cellular function and development via manipulation of surface environmental cues at the micro- and nanoscale. It is well understood that temperature plays a significant role in the rate of cellular activities, migratory behavior (thermotaxis), and in some cases, protein expression. Yet, the effects and possible utilization of micrometer-scale temperature fields in cell cultures have not been explored. Toward this end, two types of thermally isolated microheated substrates were designed and fabricated, one with standard backside etching beneath a dielectric film and another with a combination of surface and bulk micromachining and backside etching. The substrates were characterized with infrared microscopy, finite element modeling, scanning electron microscopy, stylus profilometry, and electrothermal calibrations. Neuron culture studies were conducted on these substrates to 1) examine the feasibility of using a microheated environment to achieve patterned cell growth and 2) selectively accelerate neural development on regions less than 100wide. Results show that attached neurons, grown on microheated regions set at 37, extended processes substantially faster than those incubated at 25on the same substrate. Further, unattached neurons were positioned precisely along the length of the heater filament (operating at 45) using free convection currents. These preliminary findings indicate that microheated substrates may be used to direct cellular development spatially in a practical manner.$hfillhbox[1414]
The Problem of Large Leptonic Mixing
Unlike in the quark sector where simple permutation symmetries can
generate the general features of quark masses and mixings, we find it
impossible (under conditions of hierarchy for the charged leptons and without
considering the see-saw mechanism or a more elaborate extension of the SM) to
guarantee large leptonic mixing angles with any general symmetry or
transformation of only known particles. If such symmetries exist, they must be
realized in more extended scenarios.Comment: RevTeX, 4 pages, no figure
Evidence for SU(3) symmetry breaking from hyperon production
We examine the SU(3) symmetry breaking in hyperon semileptonic decays (HSD)
by considering two typical sets of quark contributions to the spin content of
the octet baryons: Set-1 with SU(3) flavor symmetry and Set-2 with SU(3) flavor
symmetry breaking in HSD. The quark distributions of the octet baryons are
calculated with a successful statistical model. Using an approximate relation
between the quark fragmentation functions and the quark distributions, we
predict polarizations of the octet baryons produced in annihilation
and semi-inclusive deeply lepton-nucleon scattering in order to reveal the
SU(3) symmetry breaking effect on the spin structure of the octet baryons. We
find that the SU(3) symmetry breaking significantly affects the hyperon
polarization. The available experimental data on the polarization
seem to favor the theoretical predictions with SU(3) symmetry breaking. We
conclude that there is a possibility to get a collateral evidence for SU(3)
symmetry breaking from hyperon production. The theoretical errors for our
predictions are discussed.Comment: 3 tables, 14 figure
Isospin influences on particle emission and critical phenomenon in nuclear dissociation
Features of particle emission and critical point behavior are investigated as
functions of the isospin of disassembling sources and temperature at a moderate
freeze-out density for medium-size Xe isotopes in the framework of isospin
dependent lattice gas model. Multiplicities of emitted light particles,
isotopic and isobaric ratios of light particles show the strong dependence on
the isospin of the dissociation source, but double ratios of light isotope
pairs and the critical temperature determined by the extreme values of some
critical observables are insensitive to the isospin of the systems. Values of
the power law parameter of cluster mass distribution, mean multiplicity of
intermediate mass fragments (), information entropy () and Campi's
second moment () also show a minor dependence on the isospin of Xe
isotopes at the critical point. In addition, the slopes of the average
multiplicites of the neutrons (), protons (), charged particles
(), and IMFs (), slopes of the largest fragment mass number
(), and the excitation energy per nucleon of the disassembling source
() to temperature are investigated as well as variances of the
distributions of , , , , and . It
is found that they can be taken as additional judgements to the critical
phenomena.Comment: 9 Pages, 8 figure
Quantitative trait loci for bone traits segregating independently of those for growth in an F-2 broiler X layer cross
An F broiler-layer cross was phenotyped for 18 skeletal traits at 6, 7 and 9 weeks of age and genotyped with 120 microsatellite markers. Interval mapping identified 61 suggestive and significant QTL on 16 of the 25 linkage groups for 16 traits. Thirty-six additional QTL were identified when the assumption that QTL were fixed in the grandparent lines was relaxed. QTL with large effects on the lengths of the tarsometatarsus, tibia and femur, and the weights of the tibia and femur were identified on GGA4 between 217 and 249 cM. Six QTL for skeletal traits were identified that did not co-locate with genome wide significant QTL for body weight and two body weight QTL did not coincide with skeletal trait QTL. Significant evidence of imprinting was found in ten of the QTL and QTL x sex interactions were identified for 22 traits. Six alleles from the broiler line for weight- and size-related skeletal QTL were positive. Negative alleles for bone quality traits such as tibial dyschondroplasia, leg bowing and tibia twisting generally originated from the layer line suggesting that the allele inherited from the broiler is more protective than the allele originating from the layer
A family case of fertile human 45,X,psu dic(15;Y) males
We report on a familial case including four male probands from three generations with a 45,X,psu dic(15;Y)(p11.2;q12) karyotype. 45,X is usually associated with a female phenotype and only rarely with maleness, due to translocation of small Y chromosomal fragments to autosomes. These male patients are commonly infertile because of missing azoospermia factor regions from the Y long arm. In our familial case we found a pseudodicentric translocation chromosome, that contains almost the entire chromosomes 15 and Y. The translocation took place in an unknown male ancestor of our probands and has no apparent effect on fertility and phenotype of the carrier. FISH analysis demonstrated the deletion of the pseudoautosomal region 2 (PAR2) from the Y chromosome and the loss of the nucleolus organizing region (NOR) from chromosome 15. The formation of the psu dic(15;Y) chromosome is a reciprocal event to the formation of the satellited Y chromosome (Yqs). Statistically, the formation of 45,X,psu dic(15;Y) (p11.2;q12) is as likely as the formation of Yqs. Nevertheless, it has not been described yet. This can be explained by the dicentricity of this translocation chromosome that usually leads to mitotic instability and meiotic imbalances. A second event, a stable inactivation of one of the two centromeres is obligatory to enable the transmission of the translocation chromosome and thus a stably reduced chromosome number from father to every son in this family
d dimensional SO(d)-Higgs Models with Instanton and Sphaleron: d=2,3
The Abelian Higgs model and the Georgi-Glashow model in 2 and 3 Euclidean
dimensions respectively, support both finite size instantons and sphalerons.
The instantons are the familiar Nielsen-Oleson vortices and the 't
Hooft-Polyakov monopole solutions respectively. We have constructed the
sphaleron solutions and calculated the Chern-Simons charges N_cs for sphalerons
of both models and have constructed two types of noncontractible loops between
topologically distinct vacuua. In the 3 dimensional model, the sphaleron and
the vacuua have zero magnetic and electric flux while the configurations on the
loops have non vanishing magnetic flux.Comment: 24 pages, 3 figures, LaTe
Mapping of poverty and likely zoonoses hotspots
The objective of this report is to present data and expert knowledge on poverty and zoonoses hotspots to inform prioritisation of study areas on the transmission of disease in emerging livestock systems in the developing world, where prevention of zoonotic disease might bring greatest benefit to poor people
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