A systematic methodology to assess the impact of human factors in ship design

Evaluating ship layout for human factors (HF) issues using simulation software such as maritimeEXODUS can be a long and complex process. The analysis requires the identification of relevant evaluation scenarios; encompassing evacuation and normal operations; the development of appropriate measures which can be used to gauge the performance of crew and vessel and finally; the interpretation of considerable simulation data. Currently, the only agreed guidelines for evaluating HFs performance of ship design relate to evacuation and so conclusions drawn concerning the overall suitability of a ship design by one naval architect can be quite different from those of another. The complexity of the task grows as the size and complexity of the vessel increases and as the number and type of evaluation scenarios considered increases. Equally, it can be extremely difficult for fleet operators to set HFs design objectives for new vessel concepts. The challenge for naval architects is to develop a procedure that allows both accurate and rapid assessment of HFs issues associated with vessel layout and crew operating procedures. In this paper we present a systematic and transparent methodology for assessing the HF performance of ship design which is both discriminating and diagnostic. The methodology is demonstrated using two variants of a hypothetical naval ship

Chinese adzuki bean germplasm: 1. Evaluation of agronomic traits

A core collection of adzuki beans, representing the germplasm of Chinese land races, was screened at Warwick Australia in a replicated yield trial sown mid-summer. Grain yield, yield components, phenologic traits, vegetative characteristics, and morphologic descriptors were recorded for all accessions plus Japanese-derived check varieties. Accessions from southern China were later flowering, had smaller seed, and grew taller than those from central China. Grain yield was greatest for accessions from central China, whereas both north Chinese and Japanese check accessions were generally low yielding. The evaluation of diversity displayed trends associated with latitude of germplasm origin, which were positive or negative according to the trait. Similarly, the germplasm diversity in duration of crop growth phases and in rate of yield expression was also associated with latitude of landrace origin. Localised variations from these trends were found for seed size and for number of pods per plant. Various trends with latitude of origin were found for natural incidence of powdery mildew, for growth habit, plant height, vining and leaf colour. However, traits not associated with latitude of germplasm origin included primary and secondary seed colour, mature pod colour, and degree of branching. The evaluation suggests that selections from this greater range of genetic diversity may allow higher yielding varieties than the current Japanese-derived standards to be developed for Australia

Prevention of anxiety among at-risk children: a systematic review and meta-analysis

Background Anxiety disorders are common, often start in childhood and run a chronic course. As such there is a need for effective prevention. Methods We conducted a systematic review and meta-analyses of randomized, controlled trials to prevent the onset of anxiety disorders in ‘at risk’ young people. Diagnostic and symptom outcomes were examined. Putative moderators were tested as was publication bias. Results We included 16 trials (2545 young people). Two trials reported diagnostic outcomes, and significant effects were found for these at end-of-programme (RR = .09, 95%CI = .02 to .16), 6- (RR = .17, 95%CI = .06 to .27) and 12-month (RR = .31, 95%CI .17 to .45) follow-ups. Based on 16 trials, improved anxiety symptoms were significant compared to nonattention controls only, with small effect sizes reported by young people at the end-of-programmes, 6- and 12-month follow-ups; and by parents at the end of the programmes and 12-, but not 6-, month follow-ups. There was no evidence of significant moderation or publication bias. Conclusions Fourteen studies included children and young people who presented with elevated anxiety symptoms, but anxiety disorder was not ruled out in the participants in these studies. Hence, these studies might be reporting results of mixed prevention/early intervention programmes. Prevention programmes that target developmental risk factors, not only disorder maintaining factors, appear most promising. The clinically meaningful impact of anxiety disorder prevention programmes remains unknown

The stability of neurotropic African horsesickness virus in solutions of different chemical composition

(1) The viability of neurotropic African horsesickness virus was tested in media containing various salts, different amino acids, gelatine, "Dextran", chick embryo extract, serum saline and egg white. Of these, egg white was the medium of choice for retention of virus in a viable state. (2) The virus of horsesickness showed distinct levels of stability in the various media. The highest level of stability was found in suspensions containing 10 per cent egg white, followed by 10 per cent serum saline and 5 per cent egg white solutions. At a lower level of stability were suspensions made up in animo acids, gelatine and embryo extract. A very low level of stability was shown by suspensions of the virus in salt solutions and in solutions of "Dextran".The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

The inverse moment problem for convex polytopes

The goal of this paper is to present a general and novel approach for the reconstruction of any convex d-dimensional polytope P, from knowledge of its moments. In particular, we show that the vertices of an N-vertex polytope in R^d can be reconstructed from the knowledge of O(DN) axial moments (w.r.t. to an unknown polynomial measure od degree D) in d+1 distinct generic directions. Our approach is based on the collection of moment formulas due to Brion, Lawrence, Khovanskii-Pukhikov, and Barvinok that arise in the discrete geometry of polytopes, and what variously known as Prony's method, or Vandermonde factorization of finite rank Hankel matrices.Comment: LaTeX2e, 24 pages including 1 appendi

Assessing pesticide pollution of groundwater: current knowledge and remaining gaps

This paper summarises recent research on pesticides in groundwater in both temperate and tropical regions. Results of field, laboratory and modelling studies highlight the factors which determine the fate and behaviour of pesticides in groundwater systems. These include transport pathways from the soil to the water table and thence to supply sources, and the processes such as adsorption and degradation which can help to attenuate pesticide movement and reduce concentrations. Studies of degradation show that most compounds are likely to be much more persistent in aquifers than in soils, but below the water table the long travel times and potential for dilution may greatly reduce concentrations. The greatest risks are likely to occur in fractured aquifers with their potential for much more rapid flow. Important uncertainties and gaps in knowledge remain. Laboratory studies of degradation present difficulties of extrapolation to field conditions and provide evidence of wide variations in half-lives spatially and with time; making the choice of values for transport modelling problematic. Further work is required to improve understanding of such variations. Studies can also indicate that different degradation pathways can occur and different pesticide metabolites produced, depending onenvironmental conditions. The occurrence and behaviour of metabolites in groundwater systems is also poorly known

A perspective on the landscape problem

I discuss the historical roots of the landscape problem and propose criteria for its successful resolution. This provides a perspective to evaluate the possibility to solve it in several of the speculative cosmological scenarios under study including eternal inflation, cosmological natural selection and cyclic cosmologies.Comment: Invited contribution for a special issue of Foundations of Physics titled: Forty Years Of String Theory: Reflecting On the Foundations. 31 pages, no figure

Global Fluctuation Spectra in Big Crunch/Big Bang String Vacua

We study Big Crunch/Big Bang cosmologies that correspond to exact world-sheet superconformal field theories of type II strings. The string theory spacetime contains a Big Crunch and a Big Bang cosmology, as well as additional ``whisker'' asymptotic and intermediate regions. Within the context of free string theory, we compute, unambiguously, the scalar fluctuation spectrum in all regions of spacetime. Generically, the Big Crunch fluctuation spectrum is altered while passing through the bounce singularity. The change in the spectrum is characterized by a function $\Delta$, which is momentum and time-dependent. We compute $\Delta$ explicitly and demonstrate that it arises from the whisker regions. The whiskers are also shown to lead to ``entanglement'' entropy in the Big Bang region. Finally, in the Milne orbifold limit of our superconformal vacua, we show that $\Delta\to 1$ and, hence, the fluctuation spectrum is unaltered by the Big Crunch/Big Bang singularity. We comment on, but do not attempt to resolve, subtleties related to gravitational backreaction and light winding modes when interactions are taken into account.Comment: 68 pages, 1 figure; typos correcte

Fifteen years of clinical liver transplantation

Liver transplantation in humans was first attempted more than 15 yr ago. The 1-yr survival has slowly improved until it has now reached about 50%. In our experience, 46 patients have lived for at least 1 yr, with the longest survival being 9 yr. The high acute mortality in early trials was due in many cases to technical and management errors and to the use of damaged organs. With elimination of such factors, survival increased. Further improvements will depend upon better immunosuppression. Orthotopic liver transplantation (liver replacement) is the preferred operation in most cases, but placement of an extra liver (auxiliary transplantation) may have a role under special circumstances. © 1979