843 research outputs found
Viewing the efficiency of chaos control
This paper aims to cast some new light on controlling chaos using the OGY-
and the Zero-Spectral-Radius methods. In deriving those methods we use a
generalized procedure differing from the usual ones. This procedure allows us
to conveniently treat maps to be controlled bringing the orbit to both various
saddles and to sources with both real and complex eigenvalues. We demonstrate
the procedure and the subsequent control on a variety of maps. We evaluate the
control by examining the basins of attraction of the relevant controlled
systems graphically and in some cases analytically
Discrete molecular dynamics simulations of peptide aggregation
We study the aggregation of peptides using the discrete molecular dynamics
simulations. At temperatures above the alpha-helix melting temperature of a
single peptide, the model peptides aggregate into a multi-layer parallel
beta-sheet structure. This structure has an inter-strand distance of 0.48 nm
and an inter-sheet distance of 1.0 nm, which agree with experimental
observations. In this model, the hydrogen bond interactions give rise to the
inter-strand spacing in beta-sheets, while the Go interactions among side
chains make beta-strands parallel to each other and allow beta-sheets to pack
into layers. The aggregates also contain free edges which may allow for further
aggregation of model peptides to form elongated fibrils.Comment: 15 pages, 8 figure
Contact Interactions and Resonance-Like Physics at Present and Future Colliders from Unparticles
High scale conformal physics can lead to unusual unparticle stuff at our low
energies. In this paper we discuss how the exchange of unparticles between
Standard Model fields can lead to new contact interaction physics as well as a
pseudoresonance-like structure, an unresonance, that might be observable at the
Tevatron or LHC in, e.g., the Drell-Yan channel. The specific signatures of
this scenario are quite unique and can be used to easily identify this new
physics given sufficient integrated luminosity.Comment: 20 pages, 10 figs; minor text changes, ref added; typos correcte
Room-temperature continuous wave lasing in deep-subwavelength metallic cavities under electrical injection
Plasmonic nanolasers and spasers continue to attract a great deal of interest from the physics and nanophotonics community, with the experimental observation of lasing as a focus of research. We report the observation of continuous wave lasing in metallic cavities of deep subwavelength sizes under electrical injection, operating at room temperature. The volume of the nanolaser is as small as 0.42¿3, where ¿ = 1.55 µm is the lasing wavelength. This demonstration will help answer the question of how small a nanolaser can be made, and will likely stimulate a wide range of fundamental studies in basic laser physics and quantum optics on truly subwavelength scales. In addition, such nanolasers may lead to many potential applications, such as on-chip integrated photonic systems for communication, computing, and detection
Non-magnetic impurity scattering in a superconductor near a van Hove point: Zn versus Ni in the cuprates
We consider the effect of non-magnetic impurities in a
superconductor with \ef close to a van Hove singularity. It is shown that the
non-trivial density of states (DOS) allows for resonant scattering already at
intermediate potential strengths eV. The residual DOS at
\ef, and the \tc suppression rate are found to strongly depend on the carrier
concentration. Quantitative agreement with experiments on Zn and Ni doped
cuprates is obtained by adjusting a single parameter, .Comment: 4 pages uuencoded compressed Postscript (Minor changes
Comparison of adeno-associated virus pseudotype 1, 2, and 8 vectors administered by intramuscular injection in the treatment of murine phenylketonuria
Phenylketonuria (PKU) is caused by hepatic phenylalanine hydroxylase (PAH) deficiency and is associated with systemic accumulation of phenylalanine (Phe). Previously we demonstrated correction of murine PKU after intravenous injection of a recombinant type 2 adeno-associated viral vector pseudotyped with type 8 capsid (rAAV2/8), which successfully directed hepatic transduction and Pah gene expression. Here, we report that liver PAH activity and phenylalanine clearance were also restored in PAH-deficient mice after simple intramuscular injection of either AAV2 pseudotype 1 (rAAV2/1) or rAAV2/8 vectors. Serotype 2 AAV vector (rAAV2/2) was also investigated, but long-term phenylalanine clearance has been observed only for pseudotypes 1 and 8. Therapeutic correction was shown in both male and female mice, albeit more effectively in males, in which correction lasted for the entire period of the experiment (>1 year). Although phenylalanine levels began to rise in female mice at about 8-10 months after rAAV2/8 injection they remained only mildly hyperphenylalaninemic thereafter and subsequent supplementation with synthetic tetrahydrobiopterin resulted in a transient decrease in blood phenylalanine. Alternatively, subsequent administration of a second vector with a different AAV pseudotype to avoid immunity against the previously administrated vector was also successful for long-term treatment of female PKU mice. Overall, this relatively less invasive gene transfer approach completes our previous studies and allows comparison of complementary strategies in the development of efficient PKU gene therapy protocols
Unparticles-Higgs Interplay
We show that scalar unparticles coupled to the Standard Model Higgs at the
renormalizable level can have a dramatic impact in the breaking of the
electroweak symmetry already at tree level. In particular one can get the
proper electroweak scale without the need of a Higgs mass term in the
Lagrangian. By studying the mixed unparticle-Higgs propagator and spectral
function we also show how unparticles can shift the Higgs mass away from its
Standard Model value, \lambda v^2, and influence other Higgs boson properties.
Conversely, we study in some detail how electroweak symmetry breaking affects
the unparticle sector by breaking its conformal symmetry and generating a mass
gap. We also show that, for Higgs masses above that gap, unparticles can
increase quite significantly the Higgs width.Comment: 14 pages, 7 figures, typos correcte
B \to K(K^*) missing energy in Unparticle physics
In the present work we study the effects of an unparticle \unpart as the
possible source of missing energy in the decay . We find that the dependence of the differential branching ratio on
the ()-meson's energy in the presence of the vector unparticle
operators is very distinctive from that of the SM. Moreover, in using the
existing upper bound on decays, we have
been able to put more stringent constraints on the parameters of unparticle
stuff.Comment: 13 pages, 5 figure
Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells
10.1371/journal.pone.0017538PLoS ONE63
Origin of the photoemission final-state effects in Bi2Sr2CaCu2O8 by very-low-energy electron diffraction
Very-low-energy electron diffraction with a support of full-potential band
calculations is used to achieve the energy positions, K// dispersions,
lifetimes and Fourier compositions of the photoemission final states in
Bi2Sr2CaCu2O8 at low excitation energies. Highly structured final states
explain the dramatic matrix element effects in photoemission. Intense c(2x2)
diffraction reveals a significant extrinsic contribution to the shadow Fermi
surface. The final-state diffraction effects can be utilized to tune the
photoemission experiment on specific valence states or Fermi surface replicas.Comment: 4 pages, 3 Postscript figures, submitted to Phys. Rev. Lett; major
revision
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