A Sino-German 6cm polarisation survey of the Galactic plane - VIII. Small-diameter sources

Information of small-diameter sources is extracted from the Sino-German 6cm polarisation survey of the Galactic plane carried out with the Urumqi 25-m telescope. We performed two-dimensional elliptical Gaussian fits to the 6cm maps to obtain a list of sources with total-intensity and polarised flux densities. The source list contains 3832 sources with a fitted diameter smaller than 16 arcmin and a peak flux density exceeding 30 mJy, so about 5 times the rms noise, of the total-intensity data. The cumulative source count indicates completeness for flux densities exceeding about 60 mJy. We identify 125 linearly polarised sources at 6cm with a peak polarisation flux density greater than 10 mJy, so about 3 times the rms noise, of the polarised-intensity data. Despite lacking compact steep spectrum sources, the 6cm catalogue lists about 20 percent more sources than the Effelsberg 21cm source catalogue at the same angular resolution and for the same area. Most of the faint 6cm sources must have a flat spectrum and are either HII regions or extragalactic. When compared with the Green Bank 6cm (GB6) catalogue, we obtain higher flux densities for a number of extended sources with complex structures. Polarised 6cm sources density are uniformly distributed in Galactic latitude. Their number density decreases towards the inner Galaxy. More than 80 percent of the polarised sources are most likely extragalactic. With a few exceptions, the sources have a higher percentage polarisation at 6cm than at 21cm. Depolarisation seems to occur mostly within the sources with a minor contribution from the Galactic foreground emission.Comment: A&A accepted, 9 pages, 5 figures, Tables 1 and 2 are accessible from http://zmtt.bao.ac.cn/6cm

Cultural Representations in Indian English Language Teaching Textbooks

Culture plays an integral role in English language teaching (ELT) and is the reading components of ELT textbooks. This study explores the issue of cultural representation in ELT textbooks in India, which has received little attention in ELT research world-wide. By incorporating 10 ELT textbooks from four states, one national board from India, and a sequential mixed-method design, this research is aimed at investigating the cultural representation of the textbook content, characteristics of people in terms of race, gender and nationality, and the depth of the cultural content. While the results have revealed a general domination of cultural representations originating from Britain, including a major proportion of British, Irish, and generally White characters, a significant amount of gender bias, and overall minimal in-depth cultural engagement, there exists wide regional variations. Language teachers may adapt cultural representations that are relevant with other pedagogical resources to engage English language learners in critical pursuits

Incorporation of a selective sigma-2 receptor ligand enhances uptake of liposomes by multiple cancer cells

Background: The sigma-2 receptor is an attractive target for tumor imaging and targeted therapy because it is overexpressed in multiple types of solid tumors, including prostate cancer, breast cancer, and lung cancer. SV119 is a synthetic small molecule that binds to sigma-2 receptors with high affinity and specificity. This study investigates the utility of SV119 in mediating the selective targeting of liposomal vectors in various types of cancer cells. Methods: SV119 was covalently linked with polyethylene glycol-dioleyl amido aspartic acid conjugate (PEG-DOA) to generate a novel functional lipid, SV119-PEG-DOA. This lipid was utilized for the preparation of targeted liposomes to enhance their uptake by cancer cells. Liposomes with various SV119 densities (0, 1, 3, and 5 mole%) were prepared and their cellular uptake was investigated in several tumor cell lines. In addition, doxorubicin (DOX) was loaded into the targeted and unmodified liposomes, and the cytotoxic effect on the DU-145 cells was evaluated by MTT assay. Results: Liposomes with or without SV119-PEG-DOA both have a mean diameter of approximately 90 nm and a neutral charge. The incorporation of SV119-PEG-DOA significantly increased the cellular uptake of liposomes by the DU-145, PC-3, A549, 201T, and MCF-7 tumor cells, which was shown by fluorescence microscopy and the quantitative measurement of fluorescence intensity. In contrast, the incorporation of SV119 did not increase the uptake of liposomes by the normal BEAS-2B cells. In a time course study, the uptake of SV119 liposomes by DU-145 cells was also significantly higher at each time point compared to the unmodified liposomes. Furthermore, the DOX-loaded SV119 liposomes showed significantly higher cytotoxicity to DU-145 cells compared to the DOX-loaded unmodified liposomes. Conclusion: SV119 liposomes were developed for targeted drug delivery to cancer cells. The targeting efficiency and specificity of SV119 liposomes to cancer cells was demonstrated in vitro. The results of this study suggest that SV119-modified liposomes might be a promising drug carrier for tumor-targeted delivery. © 2012 Zhang et al, publisher and licensee Dove Medical Press Ltd

Magnetic fields of the W4 superbubble

Superbubbles and supershells are the channels for transferring mass and energy from the Galactic disk to the halo. Magnetic fields are believed to play a vital role in their evolution. We study the radio continuum and polarized emission properties of the W4 superbubble to determine its magnetic field strength. New sensitive radio continuum observations were made at 6 cm, 11 cm, and 21 cm. The total intensity measurements were used to derive the radio spectrum of the W4 superbubble. The linear polarization data were analysed to determine the magnetic field properties within the bubble shells. The observations show a multi-shell structure of the W4 superbubble. A flat radio continuum spectrum that stems from optically thin thermal emission is derived from 1.4 GHz to 4.8 GHz. By fitting a passive Faraday screen model and considering the filling factor fne , we obtain the thermal electron density ne = 1.0/\sqrt{fne} (\pm5%) cm^-3 and the strength of the line-of-sight component of the magnetic field B// = -5.0/\sqrt{fne} (\pm10%) {\mu}G (i.e. pointing away from us) within the western shell of the W4 superbubble. When the known tilted geometry of the W4 superbubble is considered, the total magnetic field Btot in its western shell is greater than 12 {\mu}G. The electron density and the magnetic field are lower and weaker in the high-latitude parts of the superbubble. The rotation measure is found to be positive in the eastern shell but negative in the western shell of the W4 superbubble, which is consistent with the case that the magnetic field in the Perseus arm is lifted up from the plane towards high latitudes. The magnetic field strength and the electron density we derived for the W4 superbubble are important parameters for evolution models of superbubbles breaking out of the Galactic plane.Comment: 13 pages, 8 figures, accepted for publication in Astronomy & Astrophysic

A Sino-German 6cm polarisation survey of the Galactic plane IX. HII regions

Large-scale radio continuum surveys provide data to get insights into the physical properties of radio sources. HII regions are prominent radio sources produced by thermal emission of ionised gas around young massive stars. We identify and analyse HII regions in the Sino-German 6cm polarisation survey of the Galactic plane. Objects with flat radio continuum spectra together with infrared and/or Halpha emission were identified as HII regions. For HII regions with small apparent sizes, we cross-matched the 6cm small-diameter source catalogue with the radio HII region catalogue compiled by Paladini and the infrared HII region catalogue based on the WISE data. Extended HII regions were identified by eye by overlaying the Paladini and the WISE HII regions onto the 6cm survey images for coincidences. The TT-plot method was employed for spectral index verification. A total of 401 HII regions were identified and their flux densities were determined with the Sino-German 6cm survey data. In the surveyed area, 76 pairs of sources are found to be duplicated in the Paladini HII region catalogue, mainly due to the non-distinction of previous observations with different angular resolutions, and 78 objects in their catalogue are misclassified as HII regions, being actually planetary nebulae, supernova remnants or extragalactic sources that have steep spectra. More than 30 HII regions and HII region candidates from our 6cm survey data, especially extended ones, do not have counterparts in the WISE HII region catalogue, of which 9 are identified for the first time. Based on the newly derived radio continuum spectra and the evidence of infrared emission, the previously identified SNRs G11.1-1.0, G20.4+0.1 and G16.4-0.5 are believed to be HII regions.Comment: version after some minor corrections and language editing, full Table 2 - 5 will appear in CDS, accepted for publication in A&

Low temperature terahertz spectroscopy of n-InSb through a magnetic field driven metal-insulator transition

We use fiber-coupled photoconductive emitters and detectors to perform terahertz (THz) spectroscopy of lightly-doped n-InSb directly in the cryogenic (1.5 K) bore of a high-field superconducting magnet. We measure transmission spectra from 0.1-1.1 THz as the sample is driven through a metal-insulator transition (MIT) by applied magnetic field. In the low-field metallic state, the data directly reveal the plasma edge and magneto-plasmon modes. With increasing field, a surprisingly broad band (0.3-0.8 THz) of low transmission appears at the onset of the MIT. This band subsequently collapses and evolves into the sharp 1s -> 2p- transition of electrons `frozen' onto isolated donors in the insulating state.Comment: 4 pages, 3 figure