34,966 research outputs found
Probing Unquenching Effects in the Gluon Polarisation in Light Mesons
We introduce an extension to the ladder truncated Bethe-Salpeter equation for
mesons and the rainbow truncated quark Dyson-Schwinger equations which includes
quark-loop corrections to the gluon propagator. This truncation scheme obeys
the axialvector Ward-Takahashi identity relating the quark self-energy and the
Bethe-Salpeter kernel. Two different approximations to the Yang-Mills sector
are used as input: the first is a sophisticated truncation of the full
Yang-Mills Dyson-Schwinger equations, the second is a phenomenologically
motivated form. We find that the spectra and decay constants of pseudoscalar
and vector mesons are overall described well for either approach. Meson mass
results for charge eigenstate vector and pseudoscalar meson masses are compared
to lattice data. The effects of unquenching the system are small but not
negligible.Comment: 26 pages, 13 figure
Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3
Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct platelet–bacterium interactions might contribute to some of these conditions; however, mechanisms of human platelet activation by E. coli leading to thrombus formation are poorly understood. While the IgG receptor FcγRIIA has a key role in platelet response to various Gram-positive species, its role in activation to Gram-negative bacteria is poorly defined. This study aimed to investigate the molecular mechanisms of human platelet activation by E. coli, including the potential role of FcγRIIA. Using light-transmission aggregometry, measurements of ATP release and tyrosine-phosphorylation, we investigated the ability of two E. coli clinical isolates to activate platelets in plasma, in the presence or absence of specific receptors and signaling inhibitors. Aggregation assays with washed platelets supplemented with IgGs were performed to evaluate the requirement of this plasma component in activation. We found a critical role for the immune receptor FcγRIIA, αIIbβ3, and Src and Syk tyrosine kinases in platelet activation in response to E. coli. IgG and αIIbβ3 engagement was required for FcγRIIA activation. Moreover, feedback mediators adenosine 5’-diphosphate (ADP) and thromboxane A₂ (TxA₂) were essential for platelet aggregation. These findings suggest that human platelet responses to E. coli isolates are similar to those induced by Gram-positive organisms. Our observations support the existence of a central FcγRIIA-mediated pathway by which human platelets respond to both Gram-negative and Gram-positive bacteria
An assessment of an F2 or N2O4 atmospheric injection from an aborted space shuttle mission
Assuming a linear relationship between the stratosphere loading of NOx and the magnitude of the ozone perturbation, the change in ozone expected to result from space shuttle ejection of N2O4 was calculated based on the ozone change that is predicted for the (much greater) NOx input that would accompany large-scale operations of SSTs. Stratospheric fluorine reactions were critically reviewed to evaluate the magnitude of fluorine induced ozone destruction relative to the reduction that would be caused by addition of an equal amount of chlorine. The predicted effect on stratospheric ozone is vanishingly small
Quark-gluon vertex dressing and meson masses beyond ladder-rainbow truncation
We include a generalized infinite class of quark-gluon vertex dressing
diagrams in a study of how dynamics beyond the ladder-rainbow truncation
influences the Bethe-Salpeter description of light quark pseudoscalar and
vector mesons. The diagrammatic specification of the vertex is mapped into a
corresponding specification of the Bethe-Salpeter kernel, which preserves
chiral symmetry. This study adopts the algebraic format afforded by the simple
interaction kernel used in previous work on this topic. The new feature of the
present work is that in every diagram summed for the vertex and the
corresponding Bethe-Salpeter kernel, each quark-gluon vertex is required to be
the self-consistent vertex solution. We also adopt from previous work the
effective accounting for the role of the explicitly non-Abelian three gluon
coupling in a global manner through one parameter determined from recent
lattice-QCD data for the vertex. With the more consistent vertex used here, the
error in ladder-rainbow truncation for vector mesons is never more than 10% as
the current quark mass is varied from the u/d region to the b region.Comment: 15 pages, 12 figure
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Scientific drilling of the Boltysh impact crater, Ukraine
Introduction: The Boltysh crater has been known for several decades and was first drilled in the 1960s as part of a study of economic oil shale deposits. Unfortunately, the cores were not curated and have been lost. We have re-drilled the impact crater and have recovered a near continuous record of ~400 m of organicrich sediments together with 15 m of suevite
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Organic geochemistry of the crater-fill sediments from Boltysh impact crater, Ukraine
The Boltysh impact crater, is a complex structure formed on the basement rocks of the Ukrainian shield which has been dated at 65.17±0.64 Ma [1]. The Boltysh crater has been know for several decades and was originally drilled in the 1960s-1980s in a study of economic oil shale deposits. Unfortunately, the cores were not curated and have been lost. However we have recently re-drilled the impact crater and have recovered a near continuous record of ~400 m of organic rich sediments deposited in a deep isolated lake which overlie the basement rocks spanning a period ~10 Ma. At 24km diameter, Boltysh will not have contributed substantially to the worldwide devastation at the end of the
Cretaceous. However, the precise age of the Boltysh impact relative to the Chicxulub impact and its location on a stable low lying coastal plain which allowed formation of the postimpact crater lake make it a particularly important locality. After the impact, the crater quickly filled with water in a short marine phase but returned to fresh water which persisted for >10Ma [2]. These strata contain a valuable record of Paleogene environmental change in central Europe, and one of very few terrestrial records of the KT event. This pre-eminent record of the Paleogene can help us to answer several related scientific questions including the relative age of Boltysh compared with Chicxulub, recovery from the impact, and later climate signals. The organic geochemistry and playnology indicate main inputs to be algal and higher plant within most of the core although there are some marked changes in inputs in some sections. A number of carbon isotope excursions are also present within the core which are currently being further investigated
Solar wind sputtering effects in the Martian atmosphere
A Monte Carlo simulation of the sputtering of the upper atmosphere of Mars by the solar wind was performed. The calculated sputtering yields imply loss rates (molecules/cm square - sec escaping the planet) for carbon dioxide, carbon, and oxygen of R(CO2) = 2.6 X 1000000/cm square - sec, R(C) = 6.6 X 1000000/cm square - sec, and R(O) = 7.7 X 1000000/cm - sec. The total mass loss by sputtering is only about 10% of that due to chemical and photo-chemical processes, but sputtering provides a major exospheric sink for carbon. The erosion process described here preferentially removes the lighter components of the atmosphere. Calculations based on a Monte Carlo simulation suggest that for a model atmosphere, 97% of the N2 and 33% of the CO2 originally present may have been sputtered away over 4.5 X 10 to the 9th power y. In the same length of time the (15)N/(14)N isotopic ratio for the bulk atmosphere would have increased by a factor 1.7
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Organic geochemistry of the Boltysh impact crater, Ukraine
The Boltysh crater has been know for several decades and was originally drilled in the 1960s - 1980s in a study of economic oil shale deposits. Unfortunately, the cores were not curated and have been lost. However we have recently re-drilled the impact crater and have recovered a near continuous record of ~400m of organic rich sediments deposited in a deep isolated lake which overly the basement rocks spanning a period ~10 Ma. The Boltysh impact crater, centred at 48°54–N and 32°15–E is a complex impact structure formed on the basement rocks of the Ukrainian shield. The age of the impact is 65.17±0.64 Ma [1]. At 24km diameter, the impact is unlikely to have contributed substantially to the worldwide devastation at the end of the Cretaceous.
However, the precise age of the Boltysh impact relative to the Chicxulub impact and its location on a stable low lying coastal plain which allowed formation of the postimpact crater lake make it a particularly important locality. After the impact, the crater quickly filled with water, and the crater lake received sediment input from the surrounding land surface for a period >10 Ma [2]. These strata contain a valuable record of Paleogene environmental change in central Europe, and one of very few terrestrial records of the KT event. This preeminent record of the Paleogene of central Europe can help us to answer several related scientific questions.
What is the relative age of Boltysh compared with Chicxulub? How long was the hydrothermal system active for after the impact event? How did the devastated area surrounding the crater recover, and how rapid was the recovery? The first sediments to be deposited in the crater lake were a series of relatively thin turbidites, the sediments then become organic rich shales and oil shales. Within the core there is ~400 m of organic rich shales/oil shales spanning a period of ~10 Ma some of which contain macrofossils such as ostracods, fish and plant fossils. Preliminary palynological studies suggest initial sedimentation was slow after the impact followed by more rapid sedimentation through the Late Paleocene. Hydrocarbons extracted from these samples are commonly dominated by terrestrial n-alkanes (Fig 1), Hopanes (including 3-methylhopanes) and steranes are also abundant and indicate the immaturity of the samples. The immaturity of samples is also evident from the abundance of hopenes, sterenes and oleanenes especially in the upper section of the core. In some of the oil shales the hopenes and sterenes are the most abundant hydrocarbons present. There is variation in the distribution of hydrocarbons/biomarkers and palynology throughout the core caused by changing inputs and environmental conditions
Full-analytic frequency-domain 1pN-accurate gravitational wave forms from eccentric compact binaries
The article provides ready-to-use 1pN-accurate frequency-domain gravitational
wave forms for eccentric nonspinning compact binaries of arbitrary mass ratio
including the first post-Newtonian (1pN) point particle corrections to the
far-zone gravitational wave amplitude, given in terms of tensor spherical
harmonics. The averaged equations for the decay of the eccentricity and growth
of radial frequency due to radiation reaction are used to provide stationary
phase approximations to the frequency-domain wave forms.Comment: 28 pages, submitted to PR
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