System Approach to the Development of Intelligent Complexes of Oncological Diagnostics

The system approach to the development of intellectual complexes in cancer diagnosis are discussed in the article. Distinctive features of this approach: the participation of pathologist at the stage of description of recognizable images (the description is based on traditional assessments of quality informative features of tumors); the set of the most similar probabilistic diagnoses is forming on the classification stage of recognition; final histological diagnosis is made by pathologist. The proposed approach has been successfully tested in clinical practice. Keywords: image processing, image description, image classification, pattern recognition, qualitative attributes of tumor images, interactive recognition, cancer diagnosis, decision support syste

МИКРОХИРУРГИЧЕСКИЕ ПОРТОКАВАЛЬНЫЕ АНАСТОМОЗЫ ПРИ ПОРТАЛЬНОЙ ГИПЕРТЕНЗИИ (ЭКСПЕРИМЕНТАЛЬНОЕ ИССЛЕДОВАНИЕ)

The section on anatomy justification of microsurgical spleno- and mesorenal anastomosisperformedona sectionmaterial (54humancadavers). The studyof topography and anatomy features of splenic, renal and superior mesenteric veins were conducted, their morphological characteristics, the histology characteristics of vascular anastomoses, the parameters of their tightness and mechanical strength. Experimental studies carried out on 48 mongrel dogs. There have been five sets of experiments. The analyses of morphological and functional status of improved vascular anastomoses in the short and long periods after surgery were accomplished.На 54 органокомплексах трупов людей изучены топографо-анатомические особенности селезеночной, почечной и верхней брыжеечной вен, их морфологические характеристики, гистотопографические характеристики сосудистых сплено- и мезентерикоренальных анастомозов, параметров их герметичности и механической прочности. Экспериментальная часть исследований выполнена на 48 беспородных собаках в 5 сериях экспериментов. Проведен анализ морфологического и функционального состояния усовершенствованных вариантов сосудистых анастомозов в ближайшем и отдаленном периодах после операции.

Реконструкция температуры деятельного слоя ледника на Западном плато Эльбруса за 1930–2008 гг.

The reconstruction of changes in the temperature of the base of the active layer (at a depth of 10 m) of the glacier on the Western plateau of Elbrus for the period 1930–2008 was performed. The temperature dynamics at this depth generally corresponds to the average annual changes in the air temperature at the height of the plateau (5100 m), since seasonal temperature fluctuations take place in the active layer. The initial data for the mathematical model are: 1) the temperature measurements in a borehole with a depth of 181.8 m, drilled on the plateau (2009); 2) vertical profile of the density of the firn/ice thickness; 3) vertical profile of the advection rate (ice speed), recently obtained from the analysis of the ice core (2015). Temperature changes are reconstructed by solving an incorrect inverse problem for the 1D heat equation with coefficients depending on the depth. The following conditions are added to the heat conduction equation: 1) the initial one that is calculated stationary temperature profile related to the beginning of the reconstruction period; 2) the boundary condition at the glacier bed – calculated permanent geothermal heat flux; 3) the condition of redefinition, i.e. distribution of the temperature measured in the borehole at the end of the reconstruction period. Solving the inverse problem, we obtain a previously unknown boundary condition on the surface which is the temperature of the active layer base as a function of time. The depth is reckoned from the base of the active layer. The method used for solving the inverse problem is the Tikhonov regularization, implemented numerically as an iterative procedure. The boundary condition on the surface (the restored function of the temperature changes) was found as a finite sum of harmonics with indeterminate coefficients. To improve the accuracy of the reconstruction, we used harmonic frequencies obtained from another indirect climate indicator – the tree-ring chronology for the Central Caucasus. Wavelet analysis was used to extract characteristic frequencies from the dendrochronological data. Our reconstruction determined the temperature changes within range from –17.7 to –15.3 °C for the investigated period. The reconstruction data were compared with independent polynomial smoothed temperature series from the studied region: with ENCEP/ENCAR reanalysis (significant correlation coefficient 0.76), as well as with temperature measurements at the Terskol (0.53) and Teberda weather stations. The reconstruction clearly reflects the main climate trends of the twentieth century: a warmer period in the 1940s, a colder period in the 1960s and 1980s, and extreme warming around 2000.На основе результатов измерения температуры в скважине глубиной 181,8 м, пробуренной в толще льда, материалов анализа ледникового керна и древесно-кольцевой хронологии выяснено, что температура основания деятельного слоя ледника (примерно 10 м ниже поверхности, где затухают межсезонные колебания температуры) за исследуемый период менялась в диапазоне от –17,7 до –15,3 °С, и это полностью соответствует изменению температуры воздуха в средней тропосфере в районе Эльбруса, оценённой по данным реанализа

MICROSURGICAL PORTOCAVAL ANASTOMOSES IN PORTAL HYPERTENSION (EXPERIMENTAL INVESTIGATION)

The section on anatomy justification of microsurgical spleno- and mesorenal anastomosisperformedona sectionmaterial (54humancadavers). The studyof topography and anatomy features of splenic, renal and superior mesenteric veins were conducted, their morphological characteristics, the histology characteristics of vascular anastomoses, the parameters of their tightness and mechanical strength. Experimental studies carried out on 48 mongrel dogs. There have been five sets of experiments. The analyses of morphological and functional status of improved vascular anastomoses in the short and long periods after surgery were accomplished

Reconstruction of the temperature in the active layer of the glacier on the Western plateau of Elbrus for 1930–2008

The reconstruction of changes in the temperature of the base of the active layer (at a depth of 10 m) of the glacier on the Western plateau of Elbrus for the period 1930–2008 was performed. The temperature dynamics at this depth generally corresponds to the average annual changes in the air temperature at the height of the plateau (5100 m), since seasonal temperature fluctuations take place in the active layer. The initial data for the mathematical model are: 1) the temperature measurements in a borehole with a depth of 181.8 m, drilled on the plateau (2009); 2) vertical profile of the density of the firn/ice thickness; 3) vertical profile of the advection rate (ice speed), recently obtained from the analysis of the ice core (2015). Temperature changes are reconstructed by solving an incorrect inverse problem for the 1D heat equation with coefficients depending on the depth. The following conditions are added to the heat conduction equation: 1) the initial one that is calculated stationary temperature profile related to the beginning of the reconstruction period; 2) the boundary condition at the glacier bed – calculated permanent geothermal heat flux; 3) the condition of redefinition, i.e. distribution of the temperature measured in the borehole at the end of the reconstruction period. Solving the inverse problem, we obtain a previously unknown boundary condition on the surface which is the temperature of the active layer base as a function of time. The depth is reckoned from the base of the active layer. The method used for solving the inverse problem is the Tikhonov regularization, implemented numerically as an iterative procedure. The boundary condition on the surface (the restored function of the temperature changes) was found as a finite sum of harmonics with indeterminate coefficients. To improve the accuracy of the reconstruction, we used harmonic frequencies obtained from another indirect climate indicator – the tree-ring chronology for the Central Caucasus. Wavelet analysis was used to extract characteristic frequencies from the dendrochronological data. Our reconstruction determined the temperature changes within range from –17.7 to –15.3 °C for the investigated period. The reconstruction data were compared with independent polynomial smoothed temperature series from the studied region: with ENCEP/ENCAR reanalysis (significant correlation coefficient 0.76), as well as with temperature measurements at the Terskol (0.53) and Teberda weather stations. The reconstruction clearly reflects the main climate trends of the twentieth century: a warmer period in the 1940s, a colder period in the 1960s and 1980s, and extreme warming around 2000

Temperature profile for glacial ice at the South Pole: Implications for life in a nearby subglacial lake

Airborne radar has detected ≈100 lakes under the Antarctic ice cap, the largest of which is Lake Vostok. International planning is underway to search in Lake Vostok for microbial life that may have evolved in isolation from surface life for millions of years. It is thought, however, that the lakes may be hydraulically interconnected. If so, unsterile drilling would contaminate not just one but many of them. Here we report measurements of temperature vs. depth down to 2,345 m in ice at the South Pole, within 10 km from a subglacial lake seen by airborne radar profiling. We infer a temperature at the 2,810-m deep base of the South Pole ice and at the lake of −9°C, which is 7°C below the pressure-induced melting temperature of freshwater ice. To produce the strong radar signal, the frozen lake must consist of a mix of sediment and ice in a flat bed, formed before permanent Antarctic glaciation. It may, like Siberian and Antarctic permafrost, be rich in microbial life. Because of its hydraulic isolation, proximity to South Pole Station infrastructure, and analog to a Martian polar cap, it is an ideal place to test a sterile drill before risking contamination of Lake Vostok. From the semiempirical expression for strain rate vs. shear stress, we estimate shear vs. depth and show that the IceCube neutrino observatory will be able to map the three-dimensional ice-flow field within a larger volume (0.5 km(3)) and at lower temperatures (−20°C to −35°C) than has heretofore been possible

Investigation of the Effect of Supersonic Flow of Dissociated Nitrogen on ZrB₂–HfB₂–SiC Ceramics Doped with 10 vol.% Carbon Nanotubes

The method of fabricating dense ultra-high temperature ceramic materials ZrB2–HfB2–SiC–CCNT was developed using a combination of sol-gel synthesis and reaction hot pressing approaches at 1800 °C. It was found that the introduction of multilayer nanotubes (10 vol.%) led to an increase in the consolidation efficiency of ceramics (at temperatures > 1600 °C). The obtained ZrB2–HfB2–SiC and ZrB2–HfB2–SiC–CCNT materials were characterized by a complex of physical and chemical analysis methods. A study of the effects on the modified sample ZrB2–HfB2–SiC–CCNT composition speed flow of partially dissociated nitrogen, using a high-frequency plasmatron, showed that, despite the relatively low temperature established on the surface (≤1585 °C), there was a significant change in the chemical composition and surface microstructure: in the near-surface layer, zirconium–hafnium carbonitride, amorphous boron nitride, and carbon were present. The latter caused changes in crucial characteristics such as the emission coefficient and surface catalyticity

Synthesis of nanocrystalline ZnO by the thermal decomposition of [Zn(H2O)(O2C5H7)(2)] in isoamyl alcohol

It was studied how the conditions of heat treatment of a [Zn(H2O)(O2C5H7)(2)] solution in isoamyl alcohol at 120-140A degrees C for 2-60 min affect the precursor decomposition mechanism and the characteristics of the obtained nanocrystalline zinc oxide. In all the cases, the product was a crystalline substance with the wurtzite structure and a size of crystallites of 14-18 nm, which was independent of the synthesis conditions. The thermal behavior and microstructure of the separated and dried nanostructured ZnO powder were investigated. It was determined how the duration and temperature of the heat treatment of the precursor solution affects the microstructure of ZnO coatings dip-coated onto glass substrates using dispersions produced at 120 and 140A degrees C. The nanosized ZnO application procedure was shown to be promising for creating a gas-sensing layer of chemical gas sensors for detecting 1% H-2 ( was 58 +/- 2 at an operating temperature of 300A degrees C) and 4 ppm NO2 ( were 15 +/- 1 and 1.9 +/- 0.1 at operating temperatures of 200 and 300A degrees C, respectively)