Point-of-contact interactive record linkage (PIRL) between demographic surveillance and health facility data in rural Tanzania

Introduction: Health and demographic surveillance systems (HDSS) have been an invaluable resource for monitoring the health status of populations, but often contain self-reported health service utilisation, which are subject to reporting bias. Objective: To implement point-of-contact interactive record linkage (PIRL) between demographic and health facility systems data, characterise attributes associated with (un)successful record linkage, and compare findings with a fully automated retrospective linkage approach. Methods: Individuals visiting the Kisesa Health Centre were matched to their HDSS records during a short up-take interview in the waiting area of the health facility. The search algorithm was used to rank potential matches, from which the true match(es) were selected after consultation with the patient. Multivariable logistic regression models were used to identify characteristics associated with being matched to an HDSS record. Records matched based on respondent's clarifications were subsequently used as the gold-standard to evaluate fully automated retrospective record linkage by calculating sensitivity and positive predictive value (PPV). Results: Among 2,624 individuals who reportedly lived in the HDSS coverage area, we matched 2,206 (84.1%) to their HDSS records. Characteristics associated with a higher odds of being matched were increased age (OR 1.07, 95% CI 1.02, 1.12; per 5-year increment), a later consent into the study (OR 2.07, 95% CI 1.37, 3.12; in the most recent six-month period), and fieldworker level of experience. The main drivers of the linkage algorithm were name, sex, year of birth, village, sub-village, and household member name. At the lowest match score threshold, automated retrospective linkage would have only correctly identified and linked 55% (1440/2612) of the records with a PPV of 55% (1440/2612). Conclusion: Where resources are available, PIRL is a viable approach to link HDSS and other administrative data sources that outperforms purely retrospective approaches

LSIMS-MS/MS of Isomeric Dipeptides

LSIMS-FAB CONDITIONS ARE OPTIMISED FOR PEPTIDE SEQUENCE DETERMI- NATION IN POSITIVE AND NEGATIVE ION MODE. ION ATTACHMENT IS PERFORMED USING SELECTED MATRIX MODIFICATIONSNA-NOT AVAILABL

Measurement of the transverse polarization of electrons emitted in neutron decay:A searchfor weak exotic couplings

First results are presented from an experiment that aims at the simultaneous determination of both transversal polarization components of electrons emitted in the decay of free neutrons — two observables that have never before been addressed experimentally. Preliminary results of the data analysis of these measurements of the R and N correlation coefficients are presented.status: publishe