No Justice Given

I’ve spent a considerable amount of time analyzing privilege and looking at how systems in the United States often work to further oppress the vulnerable, while keeping the privileged in power. I have taken note of how my light skin, middle-class background, and young, abled body has given me opportunities and advantages others don’t have. But, I hadn’t thought too deeply about the privileges that come with being a natural born, American citizen. I’ve stood up to salute the flag every day in school, watched fireworks on the fourth of July, and generally felt proud to be an American; but, this doesn’t mean I really understood the advantages I’d been afforded based on where I happened to be born. After going on an immersion trip to the U.S.-Mexican border, I understand these benefits much more deeply. [excerpt

Fearless: Gettysburg Breast Cancer Survivors

As we reach the end of Breast Cancer Awareness month, Surge would like to recognize breast cancer survivors. For today’s Fearless Friday, we are honored to highlight four brave and fearless Gettysburgians:Joyce Sprague, Academic Administrative Assistant for Women, Gender and Sexuality Studies; Anne Lane, Associate Dean of Academic Advising; Julie Ramsey, Vice President for College Life and Dean of Students; and Sandy Buhrman, Administrative Services Assistant for the Center for Career Development. These women are truly fearless for persisting in the face of adversity, advocating for other women, sharing their stories and inspiring others. [excerpt

The Space I Own

***TRIGGER WARNING: Eating Disorders*** I don’t care what anyone says—being a woman is hard. Being a young woman has its own set of complications–we experience a lot of pressure to look a certain way, to act a certain way, to have a specific friend group; to act as social butterflies and to live up to a set of socially constructed beauty standards. And there are too many girls—myself included—who have fallen victim to this impossible set of expectations. [excerpt

Access to Mental Health Care for Depression among Latina Women in Adams County

This research project focused on what barriers prevent Latina women in Adams County from accessing mental health care. A survey was distributed to 52 women over several weeks. These participants, particularly immigrant and undocumented women, have lower rates of health insurance, low incomes, and limited transportation, and the county does not have accessible, Spanish speaking mental health professionals, which makes it nearly impossible for these women to access mental healthcare in the county

Light-front model of the kaon electromagnetic current

The electromagnetic form factor is extracted from both components of the electromagnetic current: J(plus) and J(minus) with a pseudo-scalar coupling of the quarks to the kaon. In the case of J(plus) there is no pair term contribution in the Drell-Yan frame. However, J(minus) component of the electromagnetic current the pair term contribution is different from zero and is necessary include it to preserve the rotational symmetry of the current.Comment: 4 pages, 1 figure, uses World Scientific style file. To be published by World Scientific in the proceedings of the "VIII International Workshop on Hadron Physics,(HADRONS 2002)", Bento Goncalves, RS, Brazi

Nucleon-nucleon scattering within a multiple subtractive renormalization approach

A methodology to renormalize the nucleon-nucleon interaction, using a recursive multiple subtraction approach to construct the kernel of the scattering equation, is presented. We solve the subtracted scattering equation with the next-leading-order (NLO) and next-to-next-leading-order (NNLO) interactions. The results are presented for all partial waves up to $j=2$, fitted to low-energy experimental data. In our renormalizaton group invariant method, when introducing the NLO and NNLO interactions, the subtraction energy emerges as a renormalization scale and the momentum associated with it comes to be about the QCD scale ($\Lambda_{QCD}$), irrespectively to the partial wave.Comment: Final versio

Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries

<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth muscle cell proliferation and migration and neointimal macrophage content, effects associated with the inhibition of MCP-1/CCL2 production. The aim of the current study was to evaluate the efficacy of bindarit on in-stent stenosis in the preclinical porcine coronary stent model.</p> <p><b>Methods and Results:</b> One or 2 bare metal stents (Multi-Link Vision, 3.5 mm) were deployed (1:1.2 oversize ratio) in the coronary arteries of 42 pigs (20 bindarit versus 22 controls). Bindarit (50 mg/kg per day) was administered orally from 2 days before stenting until the time of euthanasia at 7 and 28 days. Bindarit caused a significant reduction in neointimal area (39.4%, P<0.001, n=9 group), neointimal thickness (51%, P<0.001), stenosis area (37%, P<0.001), and inflammatory score (40%, P<0.001) compared with control animals, whereas there was no significant difference in the injury score between the 2 groups. Moreover, treatment with bindarit significantly reduced the number of proliferating cells (by 45%, P<0.05; n=6 group) and monocyte/macrophage content (by 55%, P<0.01; n=5–6 group) in stented arteries at day 7 and 28, respectively. These effects were associated with a significant (P<0.05) reduction of MCP-1 plasma levels at day 28. In vitro data showed that bindarit (10–300 micromol/L) reduced tumor necrosis factor-alpha (50 ng/mL)–induced pig coronary artery smooth muscle cell proliferation and inhibited MCP-1 production.</p> <p><b>Conclusion:</b> Our results show the efficacy of bindarit in the prevention of porcine in-stent stenosis and support further investigation for clinical application of this compound.</p&gt

A sub-analysis of the SAGE study in Italy indicates good glycemic control in type 1 diabetes

Background and aims: Intensive glycemic control minimizes the risk of micro- and macrovascular complications in patients with type 1 diabetes (T1D). We report glycemic control in Italian participants (age groups: 26-44, 45-64, and ≥65 years) of the global SAGE study. Methods and results: The primary endpoint was proportion of participants who achieved an HbA1c <7% in predefined age groups. In the 523 patients with T1D, mean age was 44.6 years and mean body mass index (BMI) was 25 kg/m2. Mean HbA1c was 7.5% and 29.4% had HbA1c <7.0%, with the highest percentage in those 26-45 years (31.7%) and the lowest in those ≥65 years (20%). Altogether, 22.9% of patients achieved their physician-established individualized HbA1c target. Most patients had ≥1 symptomatic hypoglycemic episode in the previous 3 months (≤70 mg/dL 82.5%; ≤54 mg/dL 61%). Severe hypo- and hyperglycemia were experienced by 16.3% and 12% of patients, of which 7.1 and 9.5%, respectively, required hospitalization/emergency visits. More patients achieved HbA1c <7% with CSII (30%) than with multiple daily insulin injections (27.9%). In multivariate analysis, BMI (OR 0.94, 95% CI 0.89-0.99, p = 0.032) and adherence to diet (OR 0.36, 95% CI 0.18-0.70, p = 0.0028) were significantly associated with HbA1c <7.0%. Conclusions: Glycemic control can be considered good in the Italian SAGE cohort, especially in younger patients, who more frequently use pumps/continuous glucose monitoring. Greater patient education and use of technology may further support this achievement. Patients should be encouraged to maintain a low BMI and adhere to their diet