Flood- and Weather-Damaged Homes and Mental Health: An Analysis Using England's Mental Health Survey

There is increasing evidence that exposure to weather-related hazards like storms and floods adversely affects mental health. However, evidence of treated and untreated mental disorders based on diagnostic criteria for the general population is limited. We analysed the Adult Psychiatric Morbidity Survey, a large probability sample survey of adults in England (n = 7525), that provides the only national data on the prevalence of mental disorders assessed to diagnostic criteria. The most recent survey (2014–2015) asked participants if they had experienced damage to their home (due to wind, rain, snow or flood) in the six months prior to interview, a period that included months of unprecedented population exposure to flooding, particularly in Southern England. One in twenty (4.5%) reported living in a storm- or flood-damaged home in the previous six months. Social advantage (home ownership, higher household income) increased the odds of exposure to storm or flood damage. Exposure predicted having a common mental disorder over and above the effects of other known predictors of poor mental health. With climate change increasing the frequency and severity of storms and flooding, improving community resilience and disaster preparedness is a priority. Evidence on the mental health of exposed populations is key to building this capacity

A Surprising Lack of LGRB Metallicity Evolution with Redshift

Recent additions to the population of Long-duration Gamma Ray Burst (LGRB) host galaxies with measured metallicities and host masses allow us to investigate how the distributions of both these properties change with redshift. We form a sample out to z of 2.5 which we show does not have strong redshift dependent populations biases in mass and metallicity measurements. Using this sample, we find a surprising lack of evolution in the LGRB metallicity distribution across different redshifts and in particular the fraction of LGRB hosts with relatively high-metallicity, that is those with 12+log(O/H) > 8.4, remains essentially constant out to z = 2.5. This result is at odds with the evolution in the mass metallicity relation of typical galaxies, which become progressively more metal poor with increasing redshift. By converting the measured LGRB host masses and redshifts to expected metallicities using redshift appropriate mass-metallicity relations, we further find that the increase in LGRB host galaxy mass distribution with redshift seen in the Perley et al. (2016) SHOALS sample is consistent with that needed to preserve a non-evolving LGRB metallicity distribution. However, the estimated LGRB host metallicity distribution is at least a quarter dex higher at all redshifts than the measured metallicity distribution. This corresponds to about a factor of two in raw metallicity and resolves much of the difference between the LGRB host metallicity cutoffs determined by Graham & Fruchter (2017) and Perley et al. (2016). As LGRB hosts do not follow the general mass metallicity relations, there is no substitute for actually measuring their metallicities.Comment: 20 pages, 7 figures, 10 table

Affymetrix probes containing runs of contiguous guanines are not gene-specific

High Density Oligonucleotide arrays (HDONAs), such as the Affymetrix HG-U133A GeneChip, use sets of probes chosen to match specified genes, with the expectation that if a particular gene is highly expressed then all the probes in the designated probe set will provide a consistent message signifying the gene's presence. However, we demonstrate by data mining thousands of CEL files from NCBI's GEO database that 4G-probes (defined as probes containing sequences of four or more consecutive guanine (G) bases) do not react in the intended way. Rather, possibly due to the formation of G-quadruplexes, most 4G-probes are correlated, irrespective of the expression of the thousands of genes for which they were separately intended. It follows that 4G-probes should be ignored when calculating gene expression levels. Furthermore, future microarray designs should make no use of 4G-probes

Supersymmetric minisuperspace with non-vanishing fermion number

The Lagrangean of $N=1$ supergravity is dimensionally reduced to one (time-like) dimension assuming spatial homogeneity of any Bianchi type within class A of the classification of Ellis and McCallum. The algebra of the supersymmetry generators, the Lorentz generators, the diffeomorphism generators and the Hamiltonian generator is determined and found to close. In contrast to earlier work, infinitely many physical states with non-vanishing even fermion number are found to exist in these models, indicating that minisuperspace models in supergravity may be just as useful as in pure gravity.Comment: 4 page

Plastid redox state and sugars: Interactive regulators of nuclear-encoded photosynthetic gene expression

Feedback regulation of photosynthesis by carbon metabolites has long been recognized, but the underlying cellular mechanisms that control this process remain unclear. By using an Arabidopsis cell culture, we show that a block in photosynthetic electron flux prevents the increase in transcript levels of chlorophyll a/b-binding protein and the small subunit of Rubisco that typically occurs when intracellular sugar levels are depleted. In contrast, the expression of the nitrate reductase gene, which is induced by sugars, is not affected. These findings were confirmed in planta by using Arabidopsis carrying the firefly luciferase reporter gene fused to the plastocyanin and chlorophyll a/b-binding protein 2 gene promoters. Transcription from both promoters increases on carbohydrate depletion. Blocking photosynthetic electron transport with 3-(3',4'-dichlorophenyl)-1,1'-dimethylurea prevents this increase in transcription. We conclude that plastid-derived redox signaling can override the sugar-regulated expression of nuclear-encoded photosynthetic genes. In the sugar-response mutant, sucrose uncoupled 6 (sun6), plastocyanin-firefly luciferase transcription actually increases in response to exogenous sucrose rather than decreasing as in the wild type. Interestingly, plastid-derived redox signals do not influence this defective pattern of sugar-regulated gene expression in the sun6 mutant. A model, which invokes a positive inducer originating from the photosynthetic electron transport chain, is proposed to explain the nature of the plastid-derived signal

Seasonal variability in ichthyoplankton abundance and assemblage composition in the northern Gulf of Mexico off Alabama

Multiyear ichthyoplankton surveys used to monitor larval fish seasonality, abundance, and assemblage structure can provide early indicators of regional ecosystem changes. Numerous ichthyoplankton surveys have been conducted in the northern Gulf of Mexico, but few have had high levels of temporal resolution and sample replication. In this study, ichthyoplankton samples were collected monthly (October 2004–October 2006) at a single station off the coast of Alabama as part of a long-term biological survey. Four seasonal periods were identified from observed and historic water temperatures, including a relatively long (June–October) “summer” period (water temperature >26°C). Fish egg abundance, total larval abundance, and larval taxonomic diversity were significantly related to water temperature (but not salinity), with peaks in the spring, spring–summer, and summer periods, respectively. Larvae collected during the survey represented 58 different families, of which engraulids, sciaenids, carangids, and clupeids were the most prominent. The most abundant taxa collected were unidentified engraulids (50%), sand seatrout (Cynoscion arenarius, 7.5%), Atlantic bumper (Chloroscombrus chrysurus, 5.4%), Atlantic croaker (Micropogonias undulatus, 4.4%), Gulf menhaden (Brevoortia patronus, 3.8%), and unidentified gobiids (3.6%). Larval concentrations for dominant taxa were highly variable between years, but the timing of seasonal occurrence for these taxa was relatively consistent. Documented increases in sea surface temperature on the Alabama shelf may have various implications for larval fish dynamics, as indicated by the presence of tropical larval forms (e.g., fistularids, labrids, scarids, and acanthurids) in our ichthyoplankton collections and in recent juvenile surveys of Alabama and northern Gulf of Mexico seagrass habitats

The Precision Determination of Invisible-Particle Masses at the LHC

We develop techniques to determine the mass scale of invisible particles pair-produced at hadron colliders. We employ the constrained mass variable m_2C, which provides an event-by-event lower-bound to the mass scale given a mass difference. We complement this variable with a new variable m_2C,UB which provides an additional upper bound to the mass scale, and demonstrate its utility with a realistic case study of a supersymmetry model. These variables together effectively quantify the `kink' in the function Max m_T2 which has been proposed as a mass-determination technique for collider-produced dark matter. An important advantage of the m_2C method is that it does not rely simply on the position at the endpoint, but it uses the additional information contained in events which lie far from the endpoint. We found the mass by comparing the HERWIG generated m_2C distribution to ideal distributions for different masses. We find that for the case studied, with 100 fb^-1 of integrated luminosity (about 400 signal events), the invisible particle's mass can be measured to a precision of 4.1 GeV. We conclude that this technique's precision and accuracy is as good as, if not better than, the best known techniques for invisible-particle mass-determination at hadron colliders.Comment: 20 pages, 11 figures, minor correction