12,501 research outputs found
Compton Scattering by the Proton using a Large-Acceptance Arrangement
Compton scattering by the proton has been measured using the tagged-photon
facility at MAMI (Mainz) and the large-acceptance arrangement LARA. The new
data are interpreted in terms of dispersion theory based on the SAID-SM99K
parameterization of photo-meson amplitudes. It is found that two-pion exchange
in the t-channel is needed for a description of the data in the second
resonance region. The data are well represented if this channel is modeled by a
single pole with mass parameter m(sigma)=600 MeV. The asymptotic part of the
spin dependent amplitude is found to be well represented by pi-0-exchange in
the t-channel. A backward spin-polarizability of
gamma(pi)=(-37.1+-0.6(stat+syst)+-3.0(model))x10^{-4}fm^4 has been determined
from data of the first resonance region below 455 MeV. This value is in a good
agreement with predictions of dispersion relations and chiral pertubation
theory. From a subset of data between 280 and 360 MeV the resonance
pion-photoproduction amplitudes were evaluated leading to a E2/M1 multipole
ratio of the p-to-Delta radiative transition of EMR(340
MeV)=(-1.7+-0.4(stat+syst)+-0.2(model))%. It was found that this number is
dependent on the parameterization of photo-meson amplitudes. With the MAID2K
parameterization an E2/M1 multipole ratio of EMR(340
MeV)=(-2.0+-0.4(stat+syst)+-0.2(model))% is obtained
Outcomes of First-Line Chemotherapy in Patients with Advanced or Metastatic Leiomyosarcoma of Uterine and Non-Uterine Origin
Although leiomyosarcomas (LMSs) form the largest subgroup of soft tissue sarcomas (STSs), the efficacy of chemotherapy in this group is largely unclear, partly because older studies are contaminated with gastrointestinal stromal tumors (GISTs). In this retrospective study we investigated the outcome of first line chemotherapy in 65 patients with unresectable or metastatic LMS. The overall response rate (ORR) was 18%; and the median progression-free (PFS) and overall survival (OS) were 3.8 and 9.7 months respectively. No statistically significant differences in outcomes for uterine and non-uterine LMS were found. In non-uterine LMS, however, the PFS and OS seemed to be longer for females than for males, potentially negatively affecting outcomes in this group. If our observations are confirmed in other series, they would suggest that studies performed in STS patients should not only stratify for histological subtype but also for uterine versus non-uterine LMS and for gender
Temperature dependence of surface reconstructions of Au on Pd(110)
Surface reconstructions of Au film on Pd(110) substrate are studied using a
local Einstein approximation to quasiharmonic theory with the Sutton-Chen
interatomic potential. Temperature dependent surface free energies for
different coverages and surface structures are calculated. Experimentally
observed transformations from to and
structures can be explained in the framework of this model. Also conditions for
Stranski-Krastanov growth mode are found to comply with experiments. The domain
of validity of the model neglecting mixing entropy is analyzed.Comment: 7 pages, REVTeX two-column format, 3 postscript figures available on
request from [email protected] To appear in Phys. Rev. Letter
Characterization of Extragalactic 24micron Sources in the Spitzer First Look Survey
In this Letter, we present the initial characterization of extragalactic 24um
sources in the Spitzer First Look Survey (FLS) by examining their counterparts
at 8um and R-band. The color-color diagram of 24-to-8 vs. 24-to-0.7um is
populated with 18,734 sources brighter than the 3sigma flux limit of 110uJy,
over an area of 3.7sq.degrees. The 24-to-0.7um colors of these sources span
almost 4 orders of magnitudes, while the 24-to-8um colors distribute at least
over 2 orders of magnitudes. In addition to identifying ~30% of the total
sample with infrared quiescent, mostly low redshift galaxies, we also found
that: (1) 23% of the 24um sources (~1200/sq.degrees) have very red 24-to-8 and
24-to-0.7 colors and are probably infrared luminous starbursts with
L(IR)>3x10^(11)Lsun at z>1. In particular, 13% of the sample (660/sq.degrees)
are 24um detected only, with no detectable emission in either 8um or R-band.
These sources are the candidates for being ULIRGs at z>2. (2) 2% of the sample
(85/sq.degrees) have colors similar to dust reddened AGNs, like Mrk231 at
z~0.6-3. (3) We anticipate that some of these sources with extremely red colors
may be new types of sources, since they can not be modelled with any familiar
type of spectral energy distribution. We find that 17% of the 24um sources have
no detectable optical counterparts brighter than R limit of 25.5mag. Optical
spectroscopy of these optical extremely faint 24um sources would be very
difficult, and mid-infrared spectroscopy from the Spitzer would be critical for
understanding their physical nature (Abridged).Comment: Accepted for publication in ApJ (Spitzer Special Issue
Recommended from our members
Using Key Performance Indicators for multi-criteria traffic management strategic decisions
In recent research work (FP7 CONDUITS) a performance evaluation framework for traffic management and Intelligent Transport Systems was developed. The new framework consists of a set of Key Performance Indicators (KPIs) for the strategic themes of traffic efficiency, safety, pollution reduction and social inclusion, and the last stages of the project saw its validation through its application to four case studies. Following up from this work, this paper presents the extension of the framework for use as a prediction tool enabling urban transport authorities to assess the impacts of relevant policies and technologies before implementing them. The first stage of the extension focused on pollution reduction, and a novel decision support tool (CONDUITS_DST) integrating the respective KPI with micro-simulation modelling was developed. Case studies executed in Brussels and Zurich demonstrated the usability and viability of the tool. This paper takes the development one step further and reports on the extension of the approach, which moves from single-criterion to a multi-criteria decision support tool through the inclusion of the KPI on traffic efficiency, again based onmicro-simulation modelling outputs
Stripe-hexagon competition in forced pattern forming systems with broken up-down symmetry
We investigate the response of two-dimensional pattern forming systems with a
broken up-down symmetry, such as chemical reactions, to spatially resonant
forcing and propose related experiments. The nonlinear behavior immediately
above threshold is analyzed in terms of amplitude equations suggested for a
and ratio between the wavelength of the spatial periodic forcing
and the wavelength of the pattern of the respective system. Both sets of
coupled amplitude equations are derived by a perturbative method from the
Lengyel-Epstein model describing a chemical reaction showing Turing patterns,
which gives us the opportunity to relate the generic response scenarios to a
specific pattern forming system. The nonlinear competition between stripe
patterns and distorted hexagons is explored and their range of existence,
stability and coexistence is determined. Whereas without modulations hexagonal
patterns are always preferred near onset of pattern formation, single mode
solutions (stripes) are favored close to threshold for modulation amplitudes
beyond some critical value. Hence distorted hexagons only occur in a finite
range of the control parameter and their interval of existence shrinks to zero
with increasing values of the modulation amplitude. Furthermore depending on
the modulation amplitude the transition between stripes and distorted hexagons
is either sub- or supercritical.Comment: 10 pages, 12 figures, submitted to Physical Review
Patient perceptions of the side-effects of chemotherapy: the influence of 5HT3 antagonists.
In 1983, Coates conducted a survey that ranked the side-effects perceived by patients receiving chemotherapy in the order of their severity. Vomiting and nausea were found to be the two most distressing side-effects. They have an impact on quality of life and compliance with treatment. The development of 5HT3 antagonists has been a major step forward in the prevention and treatment of chemotherapy-induced nausea and vomiting. Presently, these antiemetics are routinely used as concomitant therapy in emetogenic chemotherapy regimens. The purpose of this study was to evaluate the impact of 5HT3 antagonists on patient perceptions of the side-effects of chemotherapy. Coates' survey was replicated in patients who received 5HT3 antagonists for acute nausea and vomiting resulting from emetogenic chemotherapy. Patients received the survey to identify those physical and non-physical side-effects that they attributed to chemotherapy and were asked to rank the five most distressing side-effects. Of the 197 patients who consented to take part in the study, 181 were evaluable. Nausea, hair loss and vomiting were described as the three most distressing side-effects of chemotherapy. Eighty per cent of all the patients actually experienced nausea and 57% experienced vomiting. Hair loss appeared to be more distressing to women (P < 0.001) but, in other aspects, gender, age and marital status did not influence the ranking of the three most distressing side-effects. Constipation was ranked as 6th and was not identified as a distressing side-effect in 1983. Nausea and vomiting remain to be the first and third most distressing side-effects of chemotherapy, even though the incidence and severity of acute nausea and vomiting are now significantly reduced
- …