Resultados negativos asociados a la medicación en pacientes medicoquirúrgicos de una institución hospitalaria

Introducción: El seguimiento farmacoterapéutico (SFT) es la actividad en la que el farmacéutico se responsabiliza de la farmacoterapia del paciente. Diferentes estudios han mostrado un efecto positivo del SFT sobre el paciente y el uso adecuado de los medicamentos. Objetivo: Determinar la incidencia de resultados negativos asociados a la medicación (RNM) en los pacientes de las especialidades medicoquirúrgicas de la Clínica San Juan de Dios-Orden Hospitalaria San Juan de Dios (Colombia). Metodología: Estudio descriptivo, que utiliza el método Dáder adaptado al contexto hospitalario. En el estudio se incluyó aleatoriamente a 52 pacientes ingresados en la unidad medicoquirúrgica entre noviembre y diciembre de 2011. Los RNM detectados se clasificaron según el Tercer Consenso de Granada. Resultados: El promedio de edad (desviación estándar) de los pacientes fue de 46,4 (20,3) años. Del total de 52 pacientes, 43 (82,7%) fueron tratados por cirugía general. Se caracterizó a los pacientes según la estancia prolongada (65,4%) y el uso de antibióticos (63,5%). Se encontraron en total 53 RNM: 30 problemas de necesidad, 8 de efectividad y 15 de seguridad. Se realizó como promedio una intervención farmacéutica por paciente, con una aceptación global del 87% (un 98,1% de ellas realizadas al médico tratante). Conclusiones: En los pacientes medicoquirúrgicos se identificó un RNM por paciente, y éstos eran susceptibles de intervención farmacéutica por parte del farmacéutico

Resultados negativos asociados a la medicación en pacientes medicoquirúrgicos de una institución hospitalaria

Introducción: El seguimiento farmacoterapéutico (SFT) es la actividad en la que el farmacéutico se responsabiliza de la farmacoterapia del paciente. Diferentes estudios han mostrado un efecto positivo del SFT sobre el paciente y el uso adecuado de los medicamentos. Objetivo: Determinar la incidencia de resultados negativos asociados a la medicación (RNM) en los pacientes de las especialidades medicoquirúrgicas de la Clínica San Juan de Dios-Orden Hospitalaria San Juan de Dios (Colombia). Metodología: Estudio descriptivo, que utiliza el método Dáder adaptado al contexto hospitalario. En el estudio se incluyó aleatoriamente a 52 pacientes ingresados en la unidad medicoquirúrgica entre noviembre y diciembre de 2011. Los RNM detectados se clasificaron según el Tercer Consenso de Granada. Resultados: El promedio de edad (desviación estándar) de los pacientes fue de 46,4 (20,3) años. Del total de 52 pacientes, 43 (82,7%) fueron tratados por cirugía general. Se caracterizó a los pacientes según la estancia prolongada (65,4%) y el uso de antibióticos (63,5%). Se encontraron en total 53 RNM: 30 problemas de necesidad, 8 de efectividad y 15 de seguridad. Se realizó como promedio una intervención farmacéutica por paciente, con una aceptación global del 87% (un 98,1% de ellas realizadas al médico tratante). Conclusiones: En los pacientes medicoquirúrgicos se identificó un RNM por paciente, y éstos eran susceptibles de intervención farmacéutica por parte del farmacéutico

On publicness theory and its implications for supply chain integration:The case of criminal justice supply chains

The literature has extensively discussed whether and how public organizations differ from private ones. Publicness theory argues that the degree of publicness is determined by ownership, funding, goal setting, and control structure of an organization. However, these theoretical ideas have not yet been extended to the interorganizational level. The need for further research is reflected in the sustained debate on the applicability of for-profit management approaches in public contexts and supply chains. Starting from the premise of the dimensional publicness theory, this study focuses on theory elaboration. We focus our empirical study on the criminal justice supply chain, which encompasses the process of bringing a criminal case to court. This chain provides an interesting public case to explore how specific dimensions of publicness affect or limit supply chain integration mechanisms. The results of our series of embedded cases focusing on Dutch criminal justice supply chains show that control structures, embodied in laws and regulations, define the governance of relationships between supply chain partners. In addition to these formalized ties, extensive known for-profit information and operational integration mechanisms can be observed, along with limited relational integration. Surprisingly, although similar integration mechanisms are used as in for-profit contexts, integration serves a different role in several of the relationships investigated: dealing with tensions stemming from the specific goal setting and stakeholders of criminal justice chains. Although our findings specifically relate to criminal justice supply chains, they have important implications for other supply chains using contracts and laws and those being selective in applying supply chain integration in cases of contrasting objectives. Moreover, we provide a stepping-stone for the extension of publicness theory to the interorganizational level

Logistics service provider selection for disaster preparation: a socio-technical systems perspective

Since 1990s, the world has seen a lot of advances in providing humanitarian aid through sophisticated logistics operations. The current consensus seems to be that humanitarian relief organizations (HROs) can improve their relief operations by collaborating with logistics service providers (CLSPs) in the commercial sector. The question remains: how can HROs select the most appropriate CLSP for disaster preparation? Despite its practical significance, no explicit effort has been done to identify the criteria/factors in prioritising and selecting a CLSP for disaster relief. The present study aims to address this gap by consolidating the list of criteria from a socio-technical systems (STS) perspective. Then, to handle the interdependence among the criteria derived from the STS, we develop a hybrid multi-criteria decision making model for CLSP selection in the disaster preparedness stage. The proposed model is then evaluated by a real-life case study, providing insights into the decision-makers in both HROs and CLSPs

Swift trust and commitment: the missing links for humanitarian supply chain coordination?

Coordination among actors in a humanitarian relief supply chain decides whether a relief operation can be or successful or not. In humanitarian supply chains, due to the urgency and importance of the situation combined with scarce resources, actors have to coordinate and trust each other in order to achieve joint goals. This paper investigated empirically the role of swift trust as mediating variable for achieving supply chain coordination. Based on commitment-trust theory we explore enablers of swift-trust and how swift trust translates into coordination through commitment. Based on a path analytic model we test data from the National Disaster Management Authority of India. Our study is the first testing commitment-trust theory (CTT) in the humanitarian context, highlighting the importance of swift trust and commitment for much thought after coordination. Furthermore, the study shows that information sharing and behavioral uncertainty reduction act as enablers for swift trust. The study findings offer practical guidance and suggest that swift trust is a missing link for the success of humanitarian supply chains

Expression of insulin-like growth factor-1 and proliferating cell nuclear antigen in human pulp cells of teeth with complete and incomplete root development

Aim To quantify the expression of insulin-like growth factor-1 (IGF-1) and proliferating cell nuclear antigen (PCNA) in human pulp cells of teeth with complete or incomplete root development, to support the specific role of IGF-1 in cell proliferation during tooth development and pulp reparative processes. Methodology Twenty six pulp samples were obtained from freshly extracted human third molars, equally divided in two groups according to root development stage (complete or incomplete root development). All samples were processed and immunostained to determine the expression of IGF-1 and PCNA in pulp cells. Sections were observed with a light microscope at 80· and morphometric analyses were performed to calculate the area of PCNA and IGF-1 immunostaining using digital image software. Mann– Whitney’s test was used to determine statistically significant differences between groups (P < 0.05) for each peptide and the co-expression of both. Results Expression of IGF-1 and PCNA was observed in all human pulp samples with a statistically significant higher expression in cells of pulps having complete root development (P = 0.0009). Conclusion Insulin-like growth factor-1 and PCNA are expressed in human pulp cells, with a significant greater expression in pulp cells of teeth having complete root development