Using Rheo-Small-Angle Neutron Scattering to Understand How Functionalised Dipeptides Form Gels

We explore the use of rheo-small-angle neutron scattering as a method to collect structural information from neutron scattering simultaneously with rheology to understand how low-molecular-weight hydrogels form and behave under shear. We examine three different gelling hydrogel systems to assess what structures are formed and how these influence the rheology. Furthermore, we probe what is happening to the network during syneresis and why the gels do not recover after an applied strain. All this information is vital when considering gels for applications such as 3D-printing and injection

Disk-Loss and Disk Renewal Phases in Classical Be Stars II. Detailed Analysis of Spectropolarimetric Data

In Wisniewski et al. 2010, paper I, we analyzed 15 years of spectroscopic and spectropolarimetric data from the Ritter and Pine Bluff Observatories of 2 Be stars, 60 Cygni and {\pi} Aquarii, when a transition from Be to B star occurred. Here we anaylize the intrinsic polarization, where we observe loop-like structures caused by the rise and fall of the polarization Balmer Jump and continuum V-band polarization being mismatched temporally with polarimetric outbursts. We also see polarization angle deviations from the mean, reported in paper I, which may be indicative of warps in the disk, blobs injected at an inclined orbit, or spiral density waves. We show our ongoing efforts to model time dependent behavior of the disk to constrain the phenomena, using 3D Monte Carlo radiative transfer codes.Comment: 2 pages, 6 figures, IAU Symposium 27

Ultrashort self-assembling Fmoc-peptide gelators for anti-infective biomaterial applications

Biomaterial related infections have a significant impact on society and are a major contributor to the growing threat of antimicrobial resistance. Current licensed antibiotic classes struggle to breakdown or penetrate the exopoly saccharide biofilm barrier, resulting insub-therapeutic concentrations of antibiotic at the surface of the biomaterial, treatment failure and increased spread of resistant isolates. This paper focuses for the first time on the ability of ultrashort Fmoc-peptide gelators to eradicate established bacterial biofilms implicated in a variety of medical device infections (Gram-positive: Staphylococcus aureus, Staphylococcusepidermidis and Gram-negative Escherichia coli, Pseudomonas aeruginosa). The effect of increasing the cationicity of the FmocFF via addition of di-lysine and di-orntithine was alsostudied with regard to antibacterial activity. Our studies demonstrated that Fmoc-peptides(FmocFF, FmocFFKK, FmocFFFKK, FmocFFOO) formed surfactant-like soft gels at concentrations of 1% w/v and above using a method of glucono-δ-Lactone pH induction. The majority of Fmoc-peptides (0.5-2% w/v) demonstrated selective action against established(grown for 24 hour) biofilms of Gram-positive and Gram-negative pathogens with FmocFF and FmocFFKK particularly promising. These results are likely to increase the clinical translation of short-peptide gelator platforms within the area of anti-infective biomaterials including as wound dressings and coatings for prostheses, catheters, heart valves and surgical tubes. In the long-term this will lead to wider treatment choices for clinicians and patients involved in the management of medical device infections and reduce the burden of antimicrobial resistance

British research in accounting and finance (2001–2007): the 2008 research assessment exercise

No abstract available

L1551NE - Discovery of a Binary Companion

L1551NE is a very young (class 0 or I) low-mass protostar located close to the well-studied L1551 IRS5. We present here evidence, from 1.3mm continuum interferometric observations at ~1'' resolution, for a binary companion to L1551NE. The companion, whose 1.3mm flux density is ~1/3 that of the primary component, is located 1.43'' (~230 A.U. at 160pc) to the southeast. The millimeterwave emission from the primary component may have been just barely resolved, with deconvolved size ~0.82"x0.70" (~131x112 A.U.). The companion emission was unresolved (<100 A.U.). The pair is embedded within a flattened circum-binary envelope of size ~5.4'' x 2.3'' (~860 x 370 A.U.). The masses of the three components (i.e. from the cicumstellar material of the primary star and its companion, and the envelope) are approximately 0.044, 0.014 and 0.023 Mo respectively.Comment: 8 pages, 1 figur

Simulating chemistry efficiently on fault-tolerant quantum computers

Quantum computers can in principle simulate quantum physics exponentially faster than their classical counterparts, but some technical hurdles remain. Here we consider methods to make proposed chemical simulation algorithms computationally fast on fault-tolerant quantum computers in the circuit model. Fault tolerance constrains the choice of available gates, so that arbitrary gates required for a simulation algorithm must be constructed from sequences of fundamental operations. We examine techniques for constructing arbitrary gates which perform substantially faster than circuits based on the conventional Solovay-Kitaev algorithm [C.M. Dawson and M.A. Nielsen, \emph{Quantum Inf. Comput.}, \textbf{6}:81, 2006]. For a given approximation error $\epsilon$, arbitrary single-qubit gates can be produced fault-tolerantly and using a limited set of gates in time which is $O(\log \epsilon)$ or $O(\log \log \epsilon)$; with sufficient parallel preparation of ancillas, constant average depth is possible using a method we call programmable ancilla rotations. Moreover, we construct and analyze efficient implementations of first- and second-quantized simulation algorithms using the fault-tolerant arbitrary gates and other techniques, such as implementing various subroutines in constant time. A specific example we analyze is the ground-state energy calculation for Lithium hydride.Comment: 33 pages, 18 figure

Higgs Mass from D-Terms: a Litmus Test

We explore supersymmetric theories in which the Higgs mass is boosted by the non-decoupling D-terms of an extended $U(1)_X$ gauge symmetry, defined here to be a general linear combination of hypercharge, baryon number, and lepton number. Crucially, the gauge coupling, $g_X$, is bounded from below to accommodate the Higgs mass, while the quarks and leptons are required by gauge invariance to carry non-zero charge under $U(1)_X$. This induces an irreducible rate, $\sigma$BR, for $pp \rightarrow X \rightarrow \ell\ell$ relevant to existing and future resonance searches, and gives rise to higher dimension operators that are stringently constrained by precision electroweak measurements. Combined, these bounds define a maximally allowed region in the space of observables, ($\sigma$BR, $m_X$), outside of which is excluded by naturalness and experimental limits. If natural supersymmetry utilizes non-decoupling D-terms, then the associated $X$ boson can only be observed within this window, providing a model independent `litmus test' for this broad class of scenarios at the LHC. Comparing limits, we find that current LHC results only exclude regions in parameter space which were already disfavored by precision electroweak data.Comment: 7 pages, 9 figure

Metamorfismo y estructura de la Formación Maimón y los Complejos Duarte y Río Verde, Cordillera Central Dominicana: implicaciones en la estructura y la evolución del primitivo Arco Isla Caribeño

El Complejo Duarte, el Complejo Río Verde y las Formaciones de Maimón y Los Ranchos, constituyen el basamento metabasáltico pre Aptiense/Albiense del Cinturón Intermedio (CI) en la Isla de La Española. En base a las asociaciones minerales presentes en las metabasitas y las condiciones P-T estimadas mediante termobarometría, en el Complejo Río Verde es posible distinguir cuatro zonas metamórficas, desde la facies de prehnita-pumpellyta (Zona I) en la base estructural, a la de los esquistos verdes (Zonas II y III) y anfibolítica (Zona IVa), hasta la facies anfibolítica superior con clinopiroxeno (Zona IVb) a techo. Las asociaciones minerales en la Zona IVb son transicionales a la facies de las granulitas básicas de baja-P y están restringidas a las anfibolitas localizadas justo bajo el contacto tectónico con la Peridotita de Loma Caribe suprayacente. El gradiente metamórfico de campo en el Complejo Río Verde es invertido y de baja-P. Las trayectorias P-T deducidas para rocas de la Zonas IVa y IVb implican dos episodios metamórficos: (a) un calentamiento en condiciones de baja-P aproximadamente isobáricas, típico de una suela metamórfica subofiolítica; y (b) la superposición de asociaciones de media-P, siguiendo un gradiente progrado de alta-P. Estas trayectorias se interpretan como el resultado de un cabalgamiento intraoceánico durante el cierre de una cuenca de tras-arco y el inicio de la subducción de las unidades componentes del Primitivo Arco Isla Caribeño en el Aptiense/Albiense, que produce las asociaciones de mayor presión. En el sector estudiado, el Complejo Duarte se subdivide en tres zonas metamórficas, desde la parte alta de la facies de los esquistos verdes (Zona A), a la facies de las anfibolitas y anfibolitas epidóticas (Zona B), hasta la facies anfibolítica superior transicional a la facies granulítica (Zona C). El gradiente metamórfico de campo es normal y aparentemente de media-P (25-30º C/km). Los niveles estructurales más bajos del complejo están ocupados por el batolito de noritas y gabro-noritas de la Jautia, que ha desarrollado en zonas de cizalla dúctil asociaciones sincinemáticas de granulitas con Grt+Opx. La edad de 89 Ma obtenida para las intrusiones de tonalitas foliadas (U-Pb en zircones), establece una edad Cretácico Superior para esta deformación principal, consistente en un cizallamiento dúctil sinmetamórfico a gran escala. Sin embargo, la deformación es muy heterogénea en el complejo, existiendo amplios sectores metamorfizados en condiciones de un bajo esfuerzo diferencial. Por lo tanto, el metamorfismo progrado del Complejo Duarte se interpreta como el resultado del engrosamiento moderado de una corteza oceánica anormalmente potente, debido a la gran acumulación de basaltos de plateau (>30 km). Las trayectorias post-pico térmico deducidas implican la descompresión y enfriamiento del complejo (84,6±0,5 Ma; edad de enfriamiento 40Ar/39Ar de moscovitas sin-Sp), durante la formación de las fábricas deformativas y miloníticas retrógradas que constituyen la foliación principal Sp. En síntesis, las rocas metamórficas del basamento del Cinturón Intermedio registran los diferentes estadios evolutivos relacionados con la acreción-obducción del plateau de Duarte al Primitivo Arco Isla Caribeño en el Aptiense/Albiense, junto con un fragmento de litosfera oceánica. Todos estos eventos predatan la colisión final arco-continente entre el arco isla Caribeño y la plataforma carbonatada de las Bahamas durante el Cretácico Superior.The mainly metabasaltic pre-Aptian/Albian basement of the Median Belt of Hispaniola includes the Duarte Complex, the Río Verde Complex and the Maimón-Los Ranchos Formations. In base to mineral assemblages present in metabasic rocks and P-T conditions estimated from thermobarometry, the Río Verde Complex is divided into four metamorphic zones and Zone IV is further subdivided into two. The metamorphic grade increase upward in the structural sequence, from prehnite-pumpellyte facies (Zone I), through greens-chist facies (Zones II and III) and amphibolite facies (Zone IVa), to upper amphibolite facies (Zone IVb), only restricted to Cpx-bearing amphibolites just below the contact with the overlying Loma Caribe Peridotite. The metamorphic field gradient is inverse and of low-P type. The P-T paths documented for Zones IVa and IVb of the Río Verde Complex involve a two-stage prograde evolution: a first event of near isobaric heating in the low-pressure field, typical of sub-ophiolite metamorphic sole rocks and characterized by critical high-grade assemblages; and a second event marked by a medium-pressure overprint of the first-stage metamorphic assemblages following a high-P gradient. These P-T paths are interpreted to result from intra-oceanic thrusting during the closure of a back-arc basin related with the Primitive Caribbean Island Arc and the onset of subduction of arc units in the Aptian/Albian time, which formed the high-pressure metamorphic overprint. The heating and development of an inverted metamorphic gradient in the sub-ophiolite Río Verde Complex, can be genetically related with the hanginwall emplacement of the hot peridotitic slice and the conductive heat transfer downward. The studied sector of the Duarte Complex (metamorphosed oceanic plateau) is divided into three metamorphic zones. Their distribution suggest that there is a temperature increase westward and downward in the structural sequence, from the upper greenschist facies (zone A), through Ep-amphibolite and amphibolite facies (zone B), to upper amphibolite transitional to lower granulite facies (zone C). The metamorphic field gradient is normal and the mid-P type (25-30º C/km). The lowest structural levels of the complex are occupied by the gabro-norites of the La Jautía batholith, which formed in ductile shear zones Grt+Opx-bearing granulites metamorphic assemblages. The 89 Ma date obtained from foliated tonalites (U-Pb in zircons) established an Upper Cretaceous age for the main ductile shearing deformation. However, the deformation is very heterogeneous in the complex, existing regionally wide metamorphic sectors without related foliation development. Therefore, the prograde metamorphism of the Duarte Complex is interpreted to result from moderated thickening of a previously thick oceanic crust, due to the great accumulation of plateau-basalts (>30 km). The post-thermal peak P-T paths suggest the unloading and cooling of the complex, during the continuous retrograde development of deformative and mylonitic non-coaxial Sp fabrics (84,6±0,5 Ma; 40 Ar/39 Ar cooling age in syn-Sp muscovite). In summary, the metamorphic rocks of the pre-Aptian/Albian basement units of the Median Belt record different stages in the history of the acretion-obduction of the Duarte plateau with the Caribbean Primitive Island Arc. All these tectonothermal events pre-date the final arc-continent collision between the Caribbean island arc and the Bahamas platform during the Late Cretaceous

Financial rogue waves

The financial rogue waves are reported analytically in the nonlinear option pricing model due to Ivancevic, which is nonlinear wave alternative of the Black-Scholes model. These solutions may be used to describe the possible physical mechanisms for rogue wave phenomenon in financial markets and related fields.Comment: 4 papges, 2 figures, Final version accepted in Commun. Theor. Phys., 201

LCF Life of NiCr-Y Coated Disk Alloys After Shot Peening, Oxidation and Hot Corrosion

In a prior companion study (Ref. 1), three different Ni-Cr coating compositions (29, 35.5, 45 wt% Cr) were applied at two thicknesses by Plasma Enhanced Magnetron Sputtering (PEMS) to two similar Ni-based disk alloys. One coating also received a thin ZrO2 overcoat. The low cycle fatigue (LCF) life of each coating was determined at 760 C and was less than that of the uncoated specimens. In this followon effort, shot peening was examined as a means to improve the as-deposited coating morphology as well as impart a residual compressive stress in the near-surface region. After evaluating the effect of the shot peening on the LCF life, the effectiveness of the shot-peened coating in protecting the disk alloy from oxidation and hot corrosion attack was evaluated. This evaluation was accomplished by exposing coated and shot-peened specimens to 500 h of oxidation followed by 50 h of hot corrosion, both at 760 C in air. These exposed specimens were then tested in fatigue and compared to similarly treated and exposed uncoated specimens. For all cases, shot peening improved the LCF life of the coated specimens. More specifically, the highest Cr coating showed the best LCF life of the coated specimens after shot peening, as well as after the environmental exposures. Characterization of the coatings after shot peening, oxidation, hot corrosion and LCF testing is presented and discussed