1,050 research outputs found
London Creative and Digital Fusion
date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000The London Creative and Digital Fusion programme of interactive, tailored and in-depth support was designed to support the UK capital’s creative and digital companies to collaborate, innovate and grow. London is a globally recognised hub for technology, design and creative genius. While many cities around the world can claim to be hubs for technology entrepreneurship, London’s distinctive potential lies in the successful fusion of world-leading technology with world-leading design and creativity. As innovation thrives at the edge, where better to innovate than across the boundaries of these two clusters and cultures? This booklet tells the story of Fusion’s innovation journey, its partners and its unique business support. Most importantly of all it tells stories of companies that, having worked with London Fusion, have innovated and grown. We hope that it will inspire others to follow and build on our beginnings.European Regional Development Fund 2007-13
Theoretical study of metal borides stability
We have recently identified metal-sandwich (MS) crystal structures and shown
with ab initio calculations that the MS lithium monoboride phases are favored
over the known stoichiometric ones under hydrostatic pressure [Phys. Rev. B 73,
180501(R) (2006)]. According to previous studies synthesized lithium monoboride
tends to be boron-deficient, however the mechanism leading to this phenomenon
is not fully understood. We propose a simple model that explains the
experimentally observed off-stoichiometry and show that compared to such
boron-deficient phases the MS-LiB compounds still have lower formation enthalpy
under high pressures. We also investigate stability of MS phases for a large
class of metal borides. Our ab initio results suggest that MS noble metal
borides are less unstable than the corresponding AlB-type phases but not
stable enough to form under equilibrium conditions.Comment: 14 pages, 15 figure
Mars climate engineering using orbiting solar reflectors
The manned mission is seen as a first step towards a Mars surface exploration base-station and, later, establishing permanent settlement. The location and use of Mars's natural resources is vital to enable cost-effective long-duration human exploration and exploitation missions as well as subsequent human colonization. Planet resources include various crust-lodged materials, a low-pressure natural atmosphere, assorted forms of utilizable energy, lower gravity than Earth's, and ground placement advantages relative to human operability and living standards. Power resources may include using solar and wind energy, importation of nuclear reactors and the harvesting of geothermal potential. In fact, a new branch of human civilization could be established permanently on Mars in the next century. But, meantime, an inventory and proper social assessment of Mars's prospective energy and material resources is required. This book investigates the possibilities and limitations of various systems supplying manned bases on Mars with energy and other vital resources. The book collects together recent proposals and innovative options and solutions. It is a useful source of condensed information for specialists involved in current and impending Mars-related activities and a good starting point for young researchers
Super-Earths: A New Class of Planetary Bodies
Super-Earths, a class of planetary bodies with masses ranging from a few
Earth-masses to slightly smaller than Uranus, have recently found a special
place in the exoplanetary science. Being slightly larger than a typical
terrestrial planet, super-Earths may have physical and dynamical
characteristics similar to those of Earth whereas unlike terrestrial planets,
they are relatively easier to detect. Because of their sizes, super-Earths can
maintain moderate atmospheres and possibly dynamic interiors with plate
tectonics. They also seem to be more common around low-mass stars where the
habitable zone is in closer distances. This article presents a review of the
current state of research on super-Earths, and discusses the models of the
formation, dynamical evolution, and possible habitability of these objects.
Given the recent advances in detection techniques, the detectability of
super-Earths is also discussed, and a review of the prospects of their
detection in the habitable zones of low-mass stars is presented.Comment: A (non-technical) review of the literature on the current state
ofresearch on super-Earths. The topics include observation, formation,
dynamical evolution, habitability, composition, interior dynamics, magnetic
field, atmosphere, and propsect of detection. The article has 44 pages, 27
figures, and 203 references. It has been accepted for publication in the
journal Contemporary Physics (2011
Geometric representation of interval exchange maps over algebraic number fields
We consider the restriction of interval exchange transformations to algebraic
number fields, which leads to maps on lattices. We characterize
renormalizability arithmetically, and study its relationships with a
geometrical quantity that we call the drift vector. We exhibit some examples of
renormalizable interval exchange maps with zero and non-zero drift vector, and
carry out some investigations of their properties. In particular, we look for
evidence of the finite decomposition property: each lattice is the union of
finitely many orbits.Comment: 34 pages, 8 postscript figure
Temperature-controlled laminar airflow in severe asthma for exacerbation reduction (The LASER Trial): study protocol for a randomised controlled trial
BackgroundAsthma affects more than 5 million patients in the United Kingdom. Nearly 500,000 of these patients have severe asthma with severe symptoms and frequent exacerbations that are inadequately controlled with available treatments. The burden of severe asthma on the NHS is enormous, accounting for 80 % of the total asthma cost (£1 billion), with frequent exacerbations and expensive medications generating much of this cost.Of those patients with severe asthma, 70 % are sensitised to indoor aeroallergens, and the level of exposure to allergens determines the symptoms; patients exposed to high levels are therefore most at risk of exacerbations and hospital admissions.The LASER trial aims to assess whether a new treatment, temperature controlled laminar airflow (TLA) delivered by the Airsonett™ device, can reduce the frequency of exacerbations in patients with severe allergic asthma by reducing exposure to aeroallergens overnight.MethodsThis multicentre study is a placebo-controlled, blinded, randomised controlled, parallel group trial. A total of 222 patients with a new or current diagnosis of severe allergic asthma will be assigned with a random element in a 1:1 ratio to receive either an active device for one year or a placebo device. The primary outcome is the frequency of severe asthma exacerbations occurring over a 12-month period, defined in accordance with the American Thoracic Society/European Respiratory Society (ATS/ERS) guidelines. Secondary outcomes include changes in asthma control, lung function, asthma-specific and global quality of life for participants and their carers, adherence to intervention, healthcare resource use and costs, and cost-effectiveness. Qualitative interviews will be conducted to elicit participant’s and their partner’s perceptions of the treatment.DiscussionEffective measures of allergen avoidance have, to date, proved elusive. The LASER trial aims to address this. The study will ascertain whether home-based nocturnal TLA usage over a 12-month period can reduce the frequency of exacerbations and improve asthma control and quality of life as compared to placebo, whilst being cost-effective and acceptable to adults with poorly controlled, severe allergic asthma. The results of this study will be widely applicable to the many patients with allergic asthma both in the UK and internationally.Trial registrationCurrent controlled trials ISRCTN46346208 (Date assigned 22 January 2014)
Making the user more efficient: Design for sustainable behaviour
User behaviour is a significant determinant of a product’s environmental impact; while engineering advances permit increased efficiency of product operation, the user’s decisions and habits ultimately have a major effect on the energy or other resources used by the product. There is thus a need to change users’ behaviour. A range of design techniques developed in diverse contexts suggest opportunities for engineers, designers and other stakeholders working in the field of sustainable innovation to affect users’ behaviour at the point of interaction with the product or system, in effect ‘making the user more efficient’. Approaches to changing users’ behaviour from a number of fields are reviewed and discussed, including: strategic design of affordances and behaviour-shaping constraints to control or affect energyor other resource-using interactions; the use of different kinds of feedback and persuasive technology techniques to encourage or guide users to reduce their environmental impact; and context-based systems which use feedback to adjust their behaviour to run at optimum efficiency and reduce the opportunity for user-affected inefficiency. Example implementations in the sustainable engineering and ecodesign field are suggested and discussed
Periodic points in random substitution subshifts
We study various aspects of periodic points for random substitution subshifts. In order to do so, we introduce a new property for random substitutions called the disjoint images condition. We provide a procedure for determining the property for compatible random substitutions—random substitutions for which a well-defined abelianisation exists. We find some simple necessary criteria for primitive, compatible random substitutions to admit periodic points in their subshifts. In the case that the random substitution further has disjoint images and is of constant length, we provide a stronger criterion. A method is outlined for enumerating periodic points of any specified length in a random substitution subshift
Effect of a magnetosphere compression on Jovian radio emissions: in situ case study using Juno data
During its 53-day polar orbit around Jupiter, Juno often crosses the
boundaries of the Jovian magnetosphere (namely the magnetopause and bow shock).
From the boundary locations, the upstream solar wind dynamic pressure can be
inferred, which in turn illustrates the state of compression or relaxation of
the system. The aim of this study is to examine Jovian radio emissions during
magnetospheric compressions, in order to determine the relationship between the
solar wind and Jovian radio emissions. In this paper, we give a complete list
of bow shock and magnetopause crossings (from June 2016 to August 2022), along
with some extra informations (e.g. solar wind dynamic pressure and position of
the standoff distances inferred from Joy et al. (2002)). We then select two
compression events that occur in succession (inferred from magnetopause
crossings) and we present a case study of the response of the Jovian radio
emissions. We demonstrate that magnetospheric compressions lead to the
activation of new radio sources. Newly activated broadband kilometric emissions
are observed almost simultaneously to compression of the magnetosphere, with
sources covering a large range of longitudes. Decametric emission sources are
seen to be activated more than one rotation later only at specific longitudes
and dusk local times. Finally, the activation of narrowband kilometric
radiation is not observed during the compression phase, but when the
magnetosphere is in its expansion phase
An Evaluation of Agreement of Breathing Rates Measured by a Novel Device, Manual Counting, and Other Techniques Used in Clinical Practice: Protocol for the Observational VENTILATE Study.
BACKGROUND: Respiratory rate (RR) is the most sensitive physiological observation to predict clinical deterioration on hospital wards, and poor clinical monitoring has been highlighted as a primary contributor to avoidable mortality. Patients in intensive care have their RR monitored continuously, but this equipment is rarely available on general hospital wards. OBJECTIVE: The primary objective is to assess the accuracy of the RespiraSense device in comparison with other methods currently used in clinical practice. The secondary objective is to assess the accuracy of the RespiraSense device in participants in different positions and when reading aloud. METHODS: A single-center, prospective observational study will investigate the agreement of the RespiraSense device as compared with other device measurements (capnography, electrocardiogram) and the current standard measurement of RR (manual counting by a trained health care professional). The different methods will be employed concurrently on the same participant as part of a single study visit. RESULTS: Recruitment to this study has not yet started as funding decisions are still pending. Therefore, results are not available at this stage. It is anticipated that the data required could be collected within 2 months of first recruitment to the study and data analysis completed within 6 months of the study start date. CONCLUSIONS: The Evaluation of Agreement of Breathing Rates Measured by a Novel Device, Manual Counting, and Other Techniques Used in Clinical Practice (VENTILATE) study will provide further validation of the use of the RespiraSense device in subjects with abnormal respiratory rates. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/15437
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