Study of moments of event shapes in e+e- annihilation using JADE data

Data from e+e- annihilation into hadrons collected by the JADE experiment at centre-of-mass energies between 14 GeV and 44 GeV were used to study moments of event shape distributions. The data were compared with Monte Carlo models and with predictions from QCD NLO order calculations. The strong coupling constant measured from the moments is alpha_S(M_Z) = 0.1286 +/- 0.0007 (stat) +/- 0.0011 (expt) +/- 0.0022 (had) +/- 0.0068 (theo), alpha_S(M_Z) = 0.1286 +/- 0.0072 (total error), consistent with the world average. However, systematic deficiencies in the QCD NLO order predictions are visible for some of the higher moments.Comment: JADE note 147 submitted as contributed paper to ICHEP 2004, corrected statistical error of 6 observable average and several typo

Measurement of the Strong Coupling Constant alpha_S from the Four-Jet Rate in e+e- Annihilation using JADE data

Data from e+e- annihilation into hadrons collected by the JADE experiment at centre-of-mass energies between 14 GeV and 44 GeV were used to study the four-jet rate as a function of the Durham algorithm's resolution parameter y_cut. The four-jet rate was compared to a QCD NLO order calculations including NLLA resummation of large logarithms. The strong coupling constant measured from the four-jet rate is alpha_S(M_Z) = 0.1169 +/- 0.0004 (stat) +/- 0.0012 (expt) +/- 0.0021 (had) +/- 0.0007 (theo), alpha_S(M_Z) = 0.1169 +/- 0.0026 (total error) in agreement with the world average.Comment: JADE note 146 submitted as contributed paper to ICHEP 200

A Measurement of the QCD Colour Factors using Event Shape Distributions at sqrt(s)=14 GeV to 189 GeV

Measurements of the QCD colour factors C_A and C_F and of the number of active quark flavours n_f in the process e+e- -> hadrons at high energy are presented. They are based on fits of O(alpha_S**2)+NLLA QCD calculations to distributions of the event shape observables 1-T, C, B_T and B_W measured at centre-of-mass energies from 14 GeV to 189 GeV. Hadronisation effects are approximated with power correction calculations which also depend on the QCD gauge structure. In this approach potential biases from hadronisation models are reduced. Our results for individually measured quantities are n_f = 5.64 +- 1.35, C_A = 2.88 +- 0.27 and C_F = 1.45 +- 0.27 in good agreement with QCD based on the SU(3) symmetry group where n_f=5 for the energies considered here, C_A=3 and C_F=4/3. From simultaneous fits of C_A and C_F we find C_A = 2.84 +- 0.24 and C_F = 1.29 +- 0.18, which is also in good agreement with the QCD expectation.Comment: accepted by European Journal of Physics

Poultry

Getting winter eggs from hens / D. C. Kennard and V. D. Chamberlin -- The protein requirements of growing pullets / R. M. Bethke, Paul R. Record and D. C. Kennard -- Coarse versus fine mash / D. C. Kennard -- Chicken vices / D. C. Kennard -- Tipping the beaks / D. C. Kennard -- Use of woven wire in poultry keeping -- Sun parlors for chick

Measurement of the strong coupling alpha_S from the three-jet rate in e+e- - annihilation using JADE data

We present a measurement of the strong coupling alpha_S using the three-jet rate measured with the Durham algorithm in e+e- -annihilation using data of the JADE experiment at centre-of-mass energies between 14 and 44 GeV. Recent theoretical improvements provide predictions of the three-jet rate in e+e- -annihilation at next-to-next-to-leading order. In this paper a measurement of the three-jet rate is used to determine the strong coupling alpha_s from a comparison to next-to-next-to-leading order predictions matched with next-to-leading logarithmic approximations and yields a value for the strong coupling alpha_S(MZ) = 0.1199+- 0.0010 (stat.) +- 0.0021 (exp.) +- 0.0054 (had.) +- 0.0007 (theo.) consistent with the world average.Comment: 27 pages, 8 figure

A Precision Calculation of the Next-to-Leading Order Energy-Energy Correlation Function

The O(alpha_s^2) contribution to the Energy-Energy Correlation function (EEC) of e+e- -> hadrons is calculated to high precision and the results are shown to be larger than previously reported. The consistency with the leading logarithm approximation and the accurate cancellation of infrared singularities exhibited by the new calculation suggest that it is reliable. We offer evidence that the source of the disagreement with previous results lies in the regulation of double singularities.Comment: 6 pages, uuencoded LaTeX and one eps figure appended Complete paper as PostScript file (125 kB) available at: http://www.phys.washington.edu/~clay/eecpaper1/paper.htm

Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism

In a previous study, Protein Kinase C iota (PRKCI) emerged as an important candidate gene for glioblastoma (GBM) stem-like cell (GSC) survival. Here, we show that PKCι is overexpressed and activated in patient derived GSCs compared with normal neural stem cells and normal brain lysate, and that silencing of PRKCI in GSCs causes apoptosis, along with loss of clonogenicity and reduced proliferation. Notably, PRKCI silencing reduces tumor growth in vivo in a xenograft mouse model. PKCι has been intensively studied as a therapeutic target in non-small cell lung cancer, resulting in the identification of an inhibitor, aurothiomalate (ATM), which disrupts the PKCι/ERK signaling axis. However, we show that, although sensitive to pharmacological inhibition via a pseudosubstrate peptide inhibitor, GSCs are much less sensitive to ATM, suggesting that PKCι acts along a different signaling axis in GSCs. Gene expression profiling of PRKCI-silenced GSCs revealed a novel role of the Notch signaling pathway in PKCι mediated GSC survival. A proximity ligation assay showed that Notch1 and PKCι are in close proximity in GSCs. Targeting PKCι in the context of Notch signaling could be an effective way of attacking the GSC population in GBM

Low-Energy Supersymmetry and the Tevatron Bottom-Quark Cross Section

A long-standing discrepancy between the bottom-quark production cross section and predictions of perturbative quantum chromodynamics is addressed. We show that pair production of light gluinos, of mass 12 to 16 GeV, with two-body decays into bottom quarks and light bottom squarks, yields a bottom-quark production rate in agreement with hadron collider data. We examine constraints on this scenario from low-energy data and make predictions that may be tested at the next run of the Fermilab Tevatron Collider.Comment: Version in Phys. Rev. Lett., 4 pp., 1 ps fig., uses RevTeX, added why moderate gluino masses are not ruled out, updated reference