268 research outputs found

    From South of the Mason-Dixon Line to South of the Equator: A Critical Exploration of the Transnational Contours of Confederate Memory

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    The rise of the Black Lives Matter movement, of right-wing populism, and incidences of white supremacist domestic terrorism associated with the presence of Confederate iconography since 2015 in the United States has brought much attention to the issue of Confederate memory. According to a study by the Southern Poverty Law Center, as of 2018, only eight percent of graduating high school seniors can correctly identify slavery as the primary cause of the U.S. Civil War (1861-1865). This speaks to a crisis of memory and identity around what the Confederate States of America (CSA) were and how we should remember the Confederacy today.Yet, for all the scholarly work that has been done to understand the politics of Confederate memory in the United States, especially in the South, little known is the fact that thousands of Confederate soldiers and their families migrated to Brazil in light of the devastation of the war and the potential incorporation of formerly enslaved people into American society and politics associated with Reconstruction. Today, Confederate descendants in the interior of São Paulo, Brazil still celebrate their heritage with an annual festival called the Festa Confederada. A museum on the town square, too, narrates the Confederate migration from the perspective of descendants. The purpose of this dissertation is to broaden academic and public perspective on the Confederacy by exploring the transnational contours of commemoration at these sites of Confederate memory.This research is situated at the intersection of scholarly work in cultural-historical geography on the relationship between public memory, race and racism, heritage tourism, settler colonialism, Black Geographies, and regional identity. This dissertation advances understandings of public memory as socially constructed and negotiated by social groups competing over rights and recognition on the memorial landscape. Further, it examines how Confederate memory moves and takes shape across international boundaries and cross-culturally, and comes to resonate and make sense outside its traditional place of public memory in the American South. Finally, this dissertation offers sustained reflection on the challenges of working on issues of race in the Global South as a white male “gringo” American

    Personalised trails and learner profiling within e-learning environments

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    This deliverable focuses on personalisation and personalised trails. We begin by introducing and defining the concepts of personalisation and personalised trails. Personalisation requires that a user profile be stored, and so we assess currently available standard profile schemas and discuss the requirements for a profile to support personalised learning. We then review techniques for providing personalisation and some systems that implement these techniques, and discuss some of the issues around evaluating personalisation systems. We look especially at the use of learning and cognitive styles to support personalised learning, and also consider personalisation in the field of mobile learning, which has a slightly different take on the subject, and in commercially available systems, where personalisation support is found to currently be only at quite a low level. We conclude with a summary of the lessons to be learned from our review of personalisation and personalised trails

    A model for the creation of human-generated metadata within communities

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    This paper considers situations for which detailed metadata descriptions of learning resources are necessary, and focuses on human generation of such metadata. It describes a model which facilitates human production of good quality metadata by the development and use of structured vocabularies. Using examples, this model is applied to single and multiple communities of metadata creators. The approach for transferring vocabularies across communities is related to similar work on the use of ontologies to support the development of the semantic web. Notable conclusions from this work are the need to encourage collaboration between the metadata specialists, content authors and system designers, and the scope for using accurate and consistent metadata created for one context in another context by producing descriptions of the relationships between those contexts

    Personalised trails and learner profiling in an e-learning environment

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    This deliverable focuses on personalisation and personalised trails. We begin by introducing and defining the concepts of personalisation and personalised trails. Personalisation requires that a user profile be stored, and so we assess currently available standard profile schemas and discuss the requirements for a profile to support personalised learning. We then review techniques for providing personalisation and some systems that implement these techniques, and discuss some of the issues around evaluating personalisation systems. We look especially at the use of learning and cognitive styles to support personalised learning, and also consider personalisation in the field of mobile learning, which has a slightly different take on the subject, and in commercially available systems, where personalisation support is found to currently be only at quite a low level. We conclude with a summary of the lessons to be learned from our review of personalisation and personalised trails

    Analytical study of non-linear transport across a semiconductor-metal junction

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    In this paper we study analytically a one-dimensional model for a semiconductor-metal junction. We study the formation of Tamm states and how they evolve when the semi-infinite semiconductor and metal are coupled together. The non-linear current, as a function of the bias voltage, is studied using the non-equilibrium Green's function method and the density matrix of the interface is given. The electronic occupation of the sites defining the interface has strong non-linearities as function of the bias voltage due to strong resonances present in the Green's functions of the junction sites. The surface Green's function is computed analytically by solving a quadratic matrix equation, which does not require adding a small imaginary constant to the energy. The wave function for the surface states is given

    Insuring Against Losses from Transgenic Contamination: The Case of Pharmaceutical Maize

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    Concerns about the risk of food supply contamination and the resulting financial losses have limited the development and commercialization of certain pharmaceutical plants. This article develops an insurance pricing model that helps translate these concerns into a cost-benefit analysis. The model first estimates the physical dispersal of maize pollen subject to a number of weather parameters. This distribution is then validated with the limited amount of currently available field trial data. The physical distribution is then used to calculate the premium for a fair-valued insurance policy that would fund the destruction of possibly contaminated fields. The flexible framework can be readily adapted to other crops, management practices, and regions

    Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

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    Matrix metalloproteinases (MMPs) have been implicated as important factors in gliomas since they may both facilitate invasion into the surrounding brain and participate in neovascularization. We have tested the hypothesis that deregulated expression of gelatinase-A or B, or an activator of gelatinase-A, MT1-MMP, may contribute directly to human gliomas by quantifying the expression of these MMPs in 46 brain tumour specimens and seven control tissues. Quantitative RT-PCR and gelatin zymography showed that gelatinase-A in glioma specimens was higher than in normal tissue; these were significantly elevated in low grade gliomas and remained elevated in GBMs. Gelatinase-B transcript and activity levels were also higher than in normal brain and more strongly correlated with tumour grade. We did not see a close relationship between the levels of expression of MT1-MMP mRNA and amounts of activated gelatinase-A. In situ hybridization localized gelatinase-A and MT1-MMP transcripts to normal neuronal and glia, malignant glioma cells and blood vessels. In contrast, gelatinase-B showed a more restricted pattern of expression; it was strongly expressed in blood vessels at proliferating margins, as well as tumour cells in some cases. These data suggest that gelatinase-A, -B and MT1-MMP are important in the pathophysiology of human gliomas. The primary role of gelatinase-B may lie in remodelling associated with neovascularization, whereas gelatinase-A and MT1-MMP may be involved in both glial invasion and angiogenesis. © 1999 Cancer Research Campaig

    Comparison of three rapid and easy bacterial DNA extraction methods for use with quantitative real-time PCR

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    The development of fast and easy on-site molecular detection and quantification methods for hazardous microbes on solid surfaces is desirable for several applications where specialised laboratory facilities are absent. The quantification of bacterial contamination necessitates the assessment of the efficiency of the used methodology as a whole, including the preceding steps of sampling and sample processing. We used quantitative real-time polymerase chain reaction (qrtPCR) for Escherichia coli and Staphylococcus aureus to measure the recovery of DNA from defined numbers of bacterial cells that were subjected to three different DNA extraction methods: the QIAamp® DNA Mini Kit, Reischl et al.’s method and FTA® Elute. FTA® Elute significantly showed the highest median DNA extraction efficiency of 76.9% for E. coli and 108.9% for S. aureus. The Reischl et al. method and QIAamp® DNA Mini Kit inhibited the E. coli qrtPCR assay with a 10-fold decrease of detectable DNA. None of the methods inhibited the S. aureus qrtPCR assay. The FTA® Elute applicability was demonstrated with swab samples taken from the International Space Station (ISS) interior. Overall, the FTA® Elute method was found to be the most suitable to selected criteria in terms of rapidity, easiness of use, DNA extraction efficiency, toxicity, and transport and storage conditions
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