Portable Perimetry Using Eye-Tracking on a Tablet Computer—A Feasibility Assessment

Purpose: Visual field (VF) examination by standard automated perimetry (SAP) is an important method of clinical assessment. However, the complexity of the test, and its use of bulky, expensive equipment makes it impractical for case-finding. We propose and evaluate a new approach to paracentral VF assessment that combines an inexpensive eye-tracker with a portable tablet computer (“Eyecatcher”). Methods: Twenty-four eyes from 12 glaucoma patients, and 12 eyes from six age-similar controls were examined. Participants were tested monocularly (once per eye), with both the novel Eyecatcher test and traditional SAP (HFA SITA standard 24-2). For Eyecatcher, the participant's task was to simply to look at a sequence of fixed-luminance dots, presented relative to the current point of fixation. Start and end fixations were used to determine locations where stimuli were seen/unseen, and to build a continuous map of sensitivity loss across a VF of approximately 20°. Results: Eyecatcher was able to clearly separate patients from controls, and the results were consistent with those from traditional SAP. In particular, mean Eyecatcher scores were strongly correlated with mean deviation scores (r2 = 0.64, P < 0.001), and there was good concordance between corresponding VF locations (∼84%). Participants reported that Eyecatcher was more enjoyable, easier to perform, and less tiring than SAP (all P < 0.001). Conclusions: Portable perimetry using an inexpensive eye-tracker and a tablet computer is feasible, although possible means of improvement are suggested. Translational Relevance: Such a test could have significant utility as a case finding device

Difference of optical conductivity between one- and two-dimensional doped nickelates

We study the optical conductivity in doped nickelates, and find the dramatic difference of the spectrum in the gap ($\omega$\alt4 eV) between one- (1D) and two-dimensional (2D) nickelates. The difference is shown to be caused by the dependence of hopping integral on dimensionality. The theoretical results explain consistently the experimental data in 1D and 2D nickelates, Y$_{2-x}$Ca$_x$BaNiO$_5$ and La$_{2-x}$Sr$_x$NiO$_4$, respectively. The relation between the spectrum in the X-ray aborption experiments and the optical conductivity in La$_{2-x}$Sr$_x$NiO$_4$ is discussed.Comment: RevTeX, 4 pages, 4 figure

Fluctuations in Shear-Jammed States: A Statistical Ensemble Approach

Granular matter exists out of thermal equilibrium, i.e. it is athermal. While conventional equilibrium statistical mechanics is not useful for characterizing granular materials, the idea of constructing a statistical ensemble analogous to its equilibrium counterpart to describe static granular matter was proposed by Edwards and Oakshott more than two decades ago. Recent years have seen several implementations of this idea. One of these is the stress ensemble, which is based on properties of the force moment tensor, and applies to frictional and frictionless grains. We demonstrate the full utility of this statistical framework in shear jammed (SJ) experimental states [1,2], a special class of granular solids created by pure shear, which is a strictly non-equilbrium protocol for creating solids. We demonstrate that the stress ensemble provides an excellent quantitative description of fluctuations in experimental SJ states. We show that the stress fluctuations are controlled by a single tensorial quantity: the angoricity of the system, which is a direct analog of the thermodynamic temperature. SJ states exhibit significant correlations in local stresses and are thus inherently different from density-driven, isotropically jammed (IJ) states.Comment: 6 pages, 4 figure

The Low Column Density Lyman-alpha Forest

We develop an analytical method based on the lognormal approximation to compute the column density distribution of the Lyman-alpha forest in the low column density limit. We compute the column density distributions for six different cosmological models and found that the standard, COBE-normalized CDM model cannot fit the observations of the Lyman-alpha forest at z=3. The amplitude of the fluctuations in that model has to be lowered by a factor of almost 3 to match observations. However, the currently viable cosmological models like the lightly tilted COBE-normalized CDM+Lambda model, the CHDM model with 20% neutrinos, and the low-amplitude Standard CDM model are all in agreement with observations, to within the accuracy of our approximation, for the value of the cosmological baryon density at or higher than the old Standard Bing Bang Nucleosynthesis value of 0.0125 for the currently favored value of the ionizing radiation intensity. With the low value for the baryon density inferred by Hogan & Rugers (1996), the models can only marginally match observations.Comment: three postscript figures included, submitted to ApJ

Muon anomalous magnetic moment and lepton flavor violation in MSSM

We give a thorough analysis of the correlation between the muon anomalous magnetic moment and the radiative lepton flavor violating (LFV) processes within the minimal supersymmetric standard model. We find that in the case when the slepton mass eigenstates are nearly degenerate, $\delta a_\mu$, coming from SUSY contributions, hardly depends on the lepton flavor mixing and, thus, there is no direct relation between $\delta a_\mu$ and the LFV processes. On the contrary, if the first two generations' sleptons are much heavier than the 3rd one, i.e., in the effective SUSY scenario, the two quantities are closely related. In the latter scenario, the SUSY parameter space to account for the experimental $\delta a_\mu$ is quite different from the case of no lepton flavor mixing. Especially, the Higgsino mass parameter $\mu$ can be either positive or negative.Comment: 22 pages, 9 figures; Some discussions are modifie

Anti Microbial Resistance Profile of E. coli isolates From Tropical Free Range Chickens

Normal intestinal flora of humans and animals constitute enormous reservoir of resistance genes for potentially pathogenic bacteria and may serve as major indictors of selection pressure exerted by anti-microbial use in a given population. A study was conducted in September 2003 at 3 purposively selected peri-urban sites spread across 3 senatorial zones of Imo state, Nigeria to determines the anti-microbial resistance profile of commensal E. coli isolated from free range chickens. The isolates were screened for anti-microbial resistance profile against 10 antibiotics using the disc diffusion method. E. coli strains from local fowls, recorded 100 and 78.9% resistances against ampicillin and cotrimoxazole respectively, while resistance rates against ciprofloxacin, gentamycin and norfloxacin were 0.0, 5.3 and 5.3% respectively. Isolates from free-range cockerels recorded 100% resistance against norfloxacin, cotrimoxazole and ampicillin and 83.3% against nitrofurantoin. Similarly, isolates from old layers, recorded 100% resistance against nitrofurantoin, cotrimoxazole, tetracycline, chloramphenicol and ampicillin and 80% against nalidixic acid. Similar resistance trends were observed in E. coli isolates from free-range turkeys and broiler roosters against the inexpensive broad-spectrum first line antibiotics (ampicillin, nalidixic acid, cotrimoxazole, nitrofurantoin and chloramphenicol), although values varied slightly across poultry types. Resistances against gentamycin were consistently low in isolates from the different types of poultry. Twenty-nine resistance patterns were observed in the E. coli isolates with predominant patterns being distributed widely across poultry types indicating a striking diversity of resistance patterns in the areas

Why Do Granular Materials Stiffen with Shear Rate? : Test of Novel Stress-Based Statistics

Peer reviewedPublisher PD