564 research outputs found

    Dual fear phenomenon in an eco-epidemiological model with prey aggregation

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    This study presents a thorough analysis of an eco-epidemiological model that integrates infectious diseases in prey, prey aggregation, and the dual fear effect induced by predators. We establish criteria for determining the existence of equilibrium points, which carry substantial biological significance. We establish the conditions for the occurrence of Hopf, saddle-node, and transcritical bifurcations by employing fear parameters as key bifurcation parameters. Furthermore, through numerical simulations, we demonstrate the occurrence of multiple zero-Hopf (ZH) and saddle-node transcritical (SNTC) bifurcations around the endemic steady states by varying specific key parameters across the two-parametric plane. We demonstrate that the introduction of predator-induced fear, which hinders the growth rate of susceptible prey, can lead to the finite time extinction of an initially stable susceptible prey population. Finally, we discuss management strategies aimed at regulating disease transmission, focusing on fear-based interventions and selective predation via predator attack rate on infectious prey

    Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques

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    Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic stem cell transplantation, and also xenotransplantation. In the present study, 28 immunosuppressed parkinsonian Macaca fascicularis were intracerebrally injected with wild-type or CTLA4-Ig transgenic porcine xenografts to identify a suitable strategy to enable long-term cell survival, maturation, and differentiation. Nine of 28 (32%) immunosuppressed primates developed masses compatible with PTLD, located mainly in the gastrointestinal tract and/or nasal cavity. The masses were classified as monomorphic PTLD according to the World Health Organization classification. Immunohistochemistry and polymerase chain reaction (PCR) analyses revealed that the PTLDs were associated with macaca lymphocryptovirus as confirmed by double-labeling immunohistochemistry for CD20 and Epstein-Barr nuclear antigen 2 (EBNA-2), where the viral protein was located within the CD20+ neoplastic B cells. In sera from 3 distinct phases of the experimental life of the primates, testing by quantitative PCR revealed a progression of the viral load that paralleled the PTLD progression and no evidence of zoonotic transmission of porcine lymphotropic herpesvirus through xenoneuronal grafts. These data suggest that monitoring the variation of macaca lymphocryptovirus DNA in primates could be used as a possible early diagnostic tool for PTLD progression, allowing preemptive treatment such as immunosuppression therapy reduction

    Quantum privacy and quantum coherence

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    We derive a simple relation between a quantum channel's capacity to convey coherent (quantum) information and its usefulness for quantum cryptography.Comment: 6 pages RevTex; two short comments added 7 October 199

    Classical information deficit and monotonicity on local operations

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    We investigate classical information deficit: a candidate for measure of classical correlations emerging from thermodynamical approach initiated in [Phys. Rev. Lett 89, 180402]. It is defined as a difference between amount of information that can be concentrated by use of LOCC and the information contained in subsystems. We show nonintuitive fact, that one way version of this quantity can increase under local operation, hence it does not possess property required for a good measure of classical correlations. Recently it was shown by Igor Devetak, that regularised version of this quantity is monotonic under LO. In this context, our result implies that regularization plays a role of "monotoniser".Comment: 6 pages, revte

    On asymptotic continuity of functions of quantum states

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    A useful kind of continuity of quantum states functions in asymptotic regime is so-called asymptotic continuity. In this paper we provide general tools for checking if a function possesses this property. First we prove equivalence of asymptotic continuity with so-called it robustness under admixture. This allows us to show that relative entropy distance from a convex set including maximally mixed state is asymptotically continuous. Subsequently, we consider it arrowing - a way of building a new function out of a given one. The procedure originates from constructions of intrinsic information and entanglement of formation. We show that arrowing preserves asymptotic continuity for a class of functions (so-called subextensive ones). The result is illustrated by means of several examples.Comment: Minor corrections, version submitted for publicatio

    Indeterminate-length quantum coding

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    The quantum analogues of classical variable-length codes are indeterminate-length quantum codes, in which codewords may exist in superpositions of different lengths. This paper explores some of their properties. The length observable for such codes is governed by a quantum version of the Kraft-McMillan inequality. Indeterminate-length quantum codes also provide an alternate approach to quantum data compression.Comment: 32 page

    Parenting ‘gifted and talented’ children in urban areas: Parents' voices

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    This is the author's accepted manuscript. The final published article is available from the link below. Copyright © 2014 by SAGE Publications.International evidence demonstrates the importance of engaging parents in the education of their ‘high-potential’ children, yet limited research has focused on the involvement of parents from differing economic strata/backgrounds. The current study explored the dilemmas of parenting academically high-ability children from economically deprived urban areas in the UK. Data were gathered from a sample of parents whose children attended a university-based sustained intervention programme for designated ‘gifted’ pupils aged 12–16. Parental perceptions were sought in relation to (a) the usefulness/impact of the intervention programme, (b) parents’ aspirations for their children growing up in economically deprived urban areas and (c) parents’ views on the support provided by the extended family, peer groups and the wider community. The findings have significant implications for both policy and practice and, more specifically, for engaging parents in intervention programmes offered by universities and schools to children in order to increase their access to higher education and for enhancing their life chances

    Registrar wellness in Botswana: Measuring burnout and identifying ways to improve wellness

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    Background. Burnout during registrar training is high, especially in resource-limited settings where stressors are intensified. Burnout leads to decreased quality of life for doctors, poor job and patient satisfaction, and difficulty retaining doctors.Objectives. Primary: to measure burnout among registrars working at Princess Marina Hospital in Gaborone, Botswana. Secondary: to determine factors contributing to burnout and identify potential wellness interventions.Methods. The validated Maslach Burnout Inventory was used to measure the degree of emotional exhaustion, depersonalisation and personal accomplishment. Work-related difficulties and potential wellness interventions were explored through multiple-choice and open-ended questions.Results. Of 40 eligible registrars, 20 (50%) completed the survey. High levels of burnout were reported for emotional exhaustion in 65% (13/20), depersonalisation in 45% (9/20), and personal accomplishment in 35% (7/20) of registrars. A high degree of burnout was reported by 75% (15/20) of registrars in one or more domains. In the previous 7 days, registrars worked an average of 77 hours, took 1.5 overnight calls, slept 5.7 hours per night, and 53% (10/19) had ≥1 of their patients die. Five (25%) registrars considered leaving Botswana to work in another country, which correlated with those with the highest degree of burnout. The most common frustrations included insufficient salary and limited medical resources. Suggested interventions included improved mentorship and wellness lectures.Conclusions. There is a high degree of burnout, especially emotional exhaustion, among registrars. Encouragingly, most registrars have a desire to work in Botswana after training. Future research on improving registrar wellness in low-resource settings is urgently needed
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