2,140 research outputs found

    "The rising of the new sun": time within Sindiwe Magona's Mother to mother and Zakes Mda's Heart of redness

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    This thesis takes a postcolonial perspective; however, it also utilizes theories on time and culture from an anthropological foundation. To fully understand how Magona and Mda present time, I first examine the nature of time in the Xhosa culture. This exploration includes the beliefs and traditional perspectives concerning cyclical time versus linear progression. I present research the perspectives time, death, and memory, and reveal how Mda and Magona include elements of the Xhosa time concousousness in their novels. To highlight the intricacies of cyclical time in Mother to Mother and Heart of Redness, I explore the development of the traditional concepts of western time. While I utilize research revealing specific principles of time as a unit of measurement, I will utilize explorations into the psychological nature of time; while these theories are primarily used to explore human consciousness, I wish to show how Mda and Magona blur the definition of past and present within the novels. In blurring the past and the present, Mda and Magona mirror the action of the Truth and Reconciliation Commission, and speak reconciliation to the new South Africa; lastly, I explore the ways in which Mother to Mother and Heart of Redness exemplify Benedict Anderson‘s concept of an imagined community

    Holding her own : a novel

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    This creative thesis comprises the first three chapters of Holding Her Own, a novel whichexplores the career of a young warrant officer who trains on the AH-64 Apache helicopter twoyears after the United States Army lifts the ban on women in combat aviation. Seventeen-yearoldJean Pennegarde leaves her hometown in the foothills of the Rocky mountains after the towngossip spots her outside Planned Parenthood where she is trying to obtain contraception for heryounger sister, Rena. Saving her sister’s reputation is the first in a series of heroic acts that donot earn Jean the inner satisfaction she craves, and even as she proves herself competent amongan elite group of pilots, she finds that the better she gets at war, the further she drifts from peace.When Tripp Trombetta gets her pregnant on the flight out of Somalia, she faces a personal crisisthat rivals any humanitarian disaster she has yet to encounter--caring for her infant daughter.With her estranged sister refusing to disappear into her past, a man she considers a sperm donordemanding to marry her, and an insatiable baby screaming at her all through the night, Jean isgoing to have to find that which is harder than strength--forgiveness. She will either learn to livewith her mistakes and embrace her limitations or she will destroy the life and love she hascreated

    Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY

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    Fc receptors transport maternal antibodies across epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart of mammalian FcRn (a major histocompatibility complex homolog), transfers IgY across the avian yolk sac, and represents a new class of Fc receptor related to the mammalian mannose receptor family. FcRY and FcRn bind immunoglobulins at pH ≀6.5, but not pH ≄7, allowing receptor–ligand association inside intracellular vesicles and release at the pH of blood. We obtained structures of monomeric and dimeric FcRY and an FcRY–IgY complex and explored FcRY's pH-dependent binding mechanism using electron cryomicroscopy (cryoEM) and small-angle X-ray scattering. The cryoEM structure of FcRY at pH 6 revealed a compact double-ring “head,” in which the N-terminal cysteine-rich and fibronectin II domains were folded back to contact C-type lectin-like domains 1–6, and a “tail” comprising C-type lectin-like domains 7–8. Conformational changes at pH 8 created a more elongated structure that cannot bind IgY. CryoEM reconstruction of FcRY dimers at pH 6 and small-angle X-ray scattering analysis at both pH values confirmed both structures. The cryoEM structure of the FcRY–IgY revealed symmetric binding of two FcRY heads to the dimeric FcY, each head contacting the CH4 domain of one FcY chain. FcRY shares structural properties with mannose receptor family members, including a head and tail domain organization, multimerization that may regulate ligand binding, and pH-dependent conformational changes. Our results facilitate understanding of immune recognition by the structurally related mannose receptor family and comparison of diverse methods of Ig transport across evolution

    Rydberg spectra of singlet metastable states of O2

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    International audienceUpdated analyses of several singlet Rydberg states of O2 via spectra involving excitation from the metastable a1Δg and b1ÎŁg+ states are presented. The high quality FT-VUV spectra available from the DESIRS beamline at the SOLEIL synchrotron gives significantly improved spectra compared to previous work. The Rydberg states analysed include 3pπ1ÎŁu+ v=0-4, 3pσ1Πu v=0-2, 3pπ1u v=0-2, 4pπ1ÎŁu+ v=0-1, 4pσ1Πu v=0 and 4pπ1Δu v=0. This is complemented by high quality ab initio calculations on the 1ÎŁu+ and 1u Rydberg states to determine the transition moments providing the first quantitative cross sections for Rydberg – b1ÎŁg+ transitions. These are validated against the experimental data. The results suggest the most promising candidate for determining b1ÎŁg+ number density is likely to be the 1-0 band of the 4pπ1ÎŁu+ – b1ÎŁg+ transition at 131.3 nm
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