Lexical, morphological and syntactic development in toddlers between 16 and 30 months old: a comparison across European Portuguese and Galician

The main aims of this study were to investigate the relationship between the lexical size and the emergence of morphological and syntactic markers in toddlers between the ages of 16 and 30 months and to compare these results between Galician and European Portuguese. Parents of 3012 Portuguese toddlers and those of 1081 Galician toddlers completed the MacArthur–Bates Communicative Development Inventory: Words and Sentences. The results indicated that the number of words, the ability to combine words and the number of different morphemes produced increased with age. The ability to combine words was used as an indicator of syntactic development; this ability was also associated with the toddlers’ lexical size. In both samples, gender morphemes seemed to be the first to have their production generalized, followed by the plural and the past participle. The production of gender morphemes was accompanied by a small lexical size, whereas the imperfect tense and the person mark onset were associated with large lexical sizes. The implications of these results for charting the continuity between lexical, morphological and syntactical development are discussed.CiPsi - Psychology Research Centre, Uminho (UID/PSI/ 01662/2013), Portugal. National Funds through the FCT (Foundation for Science and Technology) and co-financed by European Regional Development Funds (FEDER) through the the National Strategic Reference Framework (QREN) - FCOMP- 01-0124-FEDER-029556 and through the Competitiveness and Internationalization Operational Program (POCI) with the references and POCI-01-0145-FEDER-007562CIEC – Research Centre on Child Studies, IE, UMinho (FCT R&D unit 317), Portugal. BPD/102549/2014info:eu-repo/semantics/publishedVersio

Proyecto de rehabilitaci?n de la Calle de Rodaje A, Zona de Seguridad 15 y Plataforma Norte del Aeropuerto Internacional Jorge Ch?vez

La tesis denominada ?Proyecto de Rehabilitaci?n de la Calle de Rodaje A, Zona de Seguridad 15 y Plataforma Norte del Aeropuerto Internacional Jorge Ch?vez?, se desarrolla bajo la necesidad de mejorar los procesos de gesti?n de proyectos de Constructora Kapala S.A. para la rehabilitaci?n de las pistas en tres zonas con la complejidad de la restricci?n horaria de trabajo dentro del Aeropuerto Internacional Jorge Ch?vez ubicado en el Callao. El presente trabajo basado en la metodolog?a de enfoque cualitativo utilizando la recolecci?n de datos sin medici?n num?rica para descubrir o afinar preguntas de investigaci?n en el proceso de interpretaci?n. Por tal motivo se aplicaron los conocimientos adquiridos durante la Maestr?a en Project Management, poniendo en marcha las buenas pr?cticas para la Gesti?n del Proyecto basado en la gu?a del PMBOK 6ta edici?n, con la finalidad de cumplir con la triple restricci?n de Alcance, Tiempo y Costo del proyecto. Finalmente debido a la experiencia de los integrantes del equipo multidisciplinario, se realiz? sinergia para poder plasmarlo en este trabajo y recomendamos como oportunidad de mejora implementar una Oficina de Proyectos para la gesti?n de portafolios y proyectos en la organizaci?n

Vanadium Inhalation in a Mouse Model for the Understanding of Air-Suspended Particle Systemic Repercussion

There is an increased concern about the health effects that air-suspended particles have on human health which have been dissected in animal models. Using CD-1 mouse, we explore the effects that vanadium inhalation produce in different tissues and organs. Our findings support the systemic effects of air pollution. In this paper, we describe our findings in different organs in our conditions and contrast our results with the literature

Academic language socialisation in high school writing conferences

This study examines multilingual high school writers’ individual talk with their teachers in two advanced English language development classes to observe how such talk shapes linguistically diverse adolescents’ writing. Addressing adolescent writers’ language socialization through microethnographic discourse analysis, the author argues that teachers’ oral responses during writing conferences can either scaffold or deter students’ socialization into valued ways of using academic language for school writing. She suggests what forms of oral response provide scaffolding and what forms might limit multilingual adolescent learners’ academic literacy. Constructive interactions engaged students in dialogue about their writing, and students included content or phrasing from the interaction in their texts. Unhelpful interactions failed to foster students’ language development in observable ways. Although teachers attempted to scaffold ideas and language, they often did not guide students’ discovery of appropriate forms or points. These interactions represent restrictive academic language socialization: while some students did create academic texts, they learned little about academic language use

Yeast Bax Inhibitor, Bxi1p, Is an ER-Localized Protein That Links the Unfolded Protein Response and Programmed Cell Death in Saccharomyces cerevisiae

Bax inhibitor-1 (BI-1) is an anti-apoptotic gene whose expression is upregulated in a wide range of human cancers. Studies in both mammalian and plant cells suggest that the BI-1 protein resides in the endoplasmic reticulum and is involved in the unfolded protein response (UPR) that is triggered by ER stress. It is thought to act via a mechanism involving altered calcium dynamics. In this paper, we provide evidence that the Saccharomyces cerevisiae protein encoded by the open reading frame, YNL305C, is a bona fide homolog for BI-1. First, we confirm that yeast cells from two different strain backgrounds lacking YNL305C, which we have renamed BXI1, are more sensitive to heat-shock induced cell death than wildtype controls even though they have indistinguishable growth rates at 30°C. They are also more susceptible both to ethanol-induced and to glucose-induced programmed cell death. Significantly, we show that Bxi1p-GFP colocalizes with the ER localized protein Sec63p-RFP. We have also discovered that Δbxi1 cells are not only more sensitive to drugs that induce ER stress, but also have a decreased unfolded protein response as measured with a UPRE-lacZ reporter. Finally, we have discovered that deleting BXI1 diminishes the calcium signaling response in response to the accumulation of unfolded proteins in the ER as measured by a calcineurin-dependent CDRE-lacZ reporter. In toto, our data suggests that the Bxi1p, like its metazoan homologs, is an ER-localized protein that links the unfolded protein response and programmed cell death