Feature Detection and Analysis of Pigeon Peas Using Image Processing

Image processing is one of the challenging areas in computer science which finds its application and place in almost every area of research. Pigeon peas, which are popularly called as Toor dal in India, is widely used as one of the main ingredients in food globally, as it is rich in proteins. One of the challenges faced by the food industry is in assessing the quality and the type of the grains and pulses. The quality detection by manual inspection in analysing the grains and pulses may not give accurate results compared to an automated system. For a common man, the colour, size and texture of dals are important parameters in deciding their quality. But in some cases, more the colour lesser the quality as the dals may be polished. This paper focuses on developing a model which can extract the geometrical features and analyses in classifying pigeon peas into different groups. Digital samples of both polished and unpolished pigeon peas are taken for analysing and classifying them based on three parameters: size, colour and texture. The images are processed using matlab, a software tool

Atypical presentation of neuronal ceroid lipofuscinosis type 8 in a sibling pair and review of the eye findings and neurological features.

Purpose:To report atypical presentation of neuronal ceroid lipofuscinoses type 8 (CLN8) to the eye clinic and review clinical features of CLN8. Observations:Detailed eye exam by slit lamp exam, indirect ophthalmoscopy, fundus photography, optical coherence tomography, visual fields and electroretinogram (ERG). Molecular genetic testing using Next Generation Sequencing panel (NGS) and array Comparative Genomic Hybridization (aCGH).The siblings in this study presented to the eye clinic with retinitis pigmentosa and cystoid macular edema, and a history of seizures but no severe neurocognitive deficits or regression. Genetic testing identified a c.200C > T (p.A67V) variant in the CLN8 gene and a deletion encompassing the entire gene. Electron microscopy of lymphocytes revealed fingerprint inclusions in both siblings. Conclusions:and Importance: Pathogenic variants in CLN8 account for the retinitis pigmentosa and seizures in our patients however, currently, they do not have regression or neurocognitive decline. The presentation of NCL can be very diverse and it is important for ophthalmologists to consider this in the differential diagnosis of retinal disorders with seizures or other neurological features. Molecular genetic testing of multiple genes causing isolated and syndromic eye disorders using NGS panels and aCGH along with additional complementary testing may often be required to arrive at a definitive diagnosis

Node Disjoint Random and Optimal Path Selection (NDROPS) Algorithm for Security in MANETS

Mobile Adhoc Networks are shortly called MANETs. In these types of networks, fixed infrastructures are absent and are dynamic in nature. Nodes are movable, and they are not connected with any wires. For monitoring or supervising the transmissions in MANETS, no central supervision is present. Moving nodes, dynamic topology, and absence of infrastructure are the features of MANETs. These features are advantageous where wires cannot be used and where nodes are supposed to move. But there is a problem of security. Networks are highly prone to attacks where finding the root of the cause is very hard. Many nodes disjoint routing algorithms are proposed to balance the load, to cope up with link failures, etc. This paper proposes an algorithm called Node Disjoint Random and Optimal Path Selection (NDROPS) algorithm which uses the concept of dynamic routing and node disjoint routing to provide all the above-stated advantages along with security. Routing of data packets is done through few paths which are node disjoint. The main essence of this algorithm is to distribute the data among different routes. So, a malicious node in a path can retrieve only a few packets in random.  The simulation of the proposed NDROPS algorithm is performed and the performance is compared using throughout and packet drop probability

An open-label clinical trial of agalsidase alfa enzyme replacement therapy in children with Fabry disease who are naïve to enzyme replacement therapy.

BackgroundFollowing a drug manufacturing process change, safety/efficacy of agalsidase alfa were evaluated in enzyme replacement therapy (ERT)-naïve children with Fabry disease.MethodsIn an open-label, multicenter, Phase II study (HGT-REP-084; Shire), 14 children aged ≥7 years received 0.2 mg/kg agalsidase alfa every other week for 55 weeks. Primary endpoints: safety, changes in autonomic function (2-hour Holter monitoring). Secondary endpoints: estimated glomerular filtration rate, left ventricular mass index (LVMI), midwall fractional shortening, pharmacodynamic parameters, and patient-reported quality-of-life.ResultsAmong five boys (median 10.2 [range 6.7, 14.4] years) and nine girls (14.8 [10.1, 15.9] years), eight patients experienced infusion-related adverse events (vomiting, n=4; nausea, n=3; dyspnea, n=3; chest discomfort, n=2; chills, n=2; dizziness, n=2; headache, n=2). One of these had several hypersensitivity episodes. However, no patient discontinued for safety reasons and no serious adverse events occurred. One boy developed immunoglobulin G (IgG) and neutralizing antidrug antibodies. Overall, no deterioration in cardiac function was observed in seven patients with low/abnormal SDNN (standard deviation of all filtered RR intervals; <100 ms) and no left ventricular hypertrophy: mean (SD) baseline SDNN, 81.6 (20.9) ms; mean (95% confidence interval [CI]) change from baseline to week 55, 17.4 (2.9, 31.9) ms. Changes in SDNN correlated with changes in LVMI (r=-0.975). No change occurred in secondary efficacy endpoints: mean (95% CI) change from baseline at week 55 in LVMI, 0.16 (-3.3, 3.7) g/m(2.7); midwall fractional shortening, -0.62% (-2.7%, 1.5%); estimated glomerular filtration rate, 0.15 (-11.4, 11.7) mL/min/1.73 m(2); urine protein, -1.8 (-6.0, 2.4) mg/dL; urine microalbumin, 0.6 (-0.5, 1.7) mg/dL; plasma globotriaosylceramide (Gb3), -5.71 (-10.8, -0.6) nmol/mL; urinary Gb3, -1,403.3 (-3,714.0, 907.4) nmol/g creatinine, or clinical quality-of-life outcomes.ConclusionFifty-five weeks' agalsidase alfa ERT at 0.2 mg/kg every other week was well tolerated. Disease progression may be slowed when ERT is started prior to major organ dysfunction.Trial registrationhttps://ClinicalTrials.gov identifier NCT01363492

Characteristic Study of Combined eects of MHD and Coriolis Force on Free Convection in a Rectangular Cavity with Isotropic and Anisotropic Porous Media

This investigation deals with the classic Rayleigh - Benard problem for a laminar, viscous, unsteady incompressible fluid flow heated from below is extended to three-dimensional convection in a nite geometry with isotropic and anisotropic porous media rotating with constant angular velocity and the magnetic eld is applied in the vertical direction. For the given physical set-up, governing partial differential equations are transformed to a set of non-dimensional ordinary differential equations using similarity transformation. This demands to apply Fourier series method to study the characteristic of velocity, temperature and concentration for the effect of Taylors number, Rayleigh number, Hartmanns number and Prandtl number for both anisotropic and isotropic porous media. The results of steam function and isotherms on various parameters have been discussed and found to be good agreement for the physical system

RNA Pore Translocation with Static and Periodic Forces: Effect of Secondary and Tertiary Elements on Process Activation and Duration

We use MD simulations to study the pore translocation properties of a pseudoknotted viral RNA. We consider the 71-nucleotide-long xrRNA from the Zika virus and establish how it responds when driven through a narrow pore by static or periodic forces applied to either of the two termini. Unlike the case of fluctuating homopolymers, the onset of translocation is significantly delayed with respect to the application of static driving forces. Because of the peculiar xrRNA architecture, activation times can differ by orders of magnitude at the two ends. Instead, translocation duration is much smaller than activation times and occurs on time scales comparable at the two ends. Periodic forces amplify significantly the differences at the two ends, for both activation times and translocation duration. Finally, we use a waiting-times analysis to examine the systematic slowing downs in xrRNA translocations and associate them to the hindrance of specific secondary and tertiary elements of xrRNA. The findings provide a useful reference to interpret and design future theoretical and experimental studies of RNA translocation

Pengaruh Model Experiential Learning Terhadap Keterampilan Berpikir Kritis Dan Motivasi Berprestasi Siswa

Penelitian kuasi eksperimen ini bertujuan untuk menganalisis perbedaan keterampilan berpikir kritis dan motivasi berprestasi antara siswa yang belajar dengan model experiential learning dengan siswa yang belajar dengan model pembelajaran konvensional. Untuk mencapai tujuan tersebut, dilaksanakan penelitian dengan populasi siswa kelas X MIPA semester genap di SMA Negeri 1 Semarapura tahun pelajaran 2013/2014. Berdasarkan hasil random sampling, terpilih kelas X MIPA 6 sebagai kelas eksperimen dan X MIPA 7 sebagai kelas kontrol. Data keterampilan berpikir kritis dikumpulkan dengan tes keterampilan berpikir kritis dan data motivasi berprestasi dikumpulkan dengan menggunakan kuesioner. Data yang terkumpul kemudian dianalisis dengan analisis deskriptif dan analisis multivariat. Berdasarkan hasil analisis data dan pembahasan diperoleh temuan: 1) terdapat perbedaan keterampilan berpikir kritis dan motivasi berprestasi antara siswa yang belajar dengan model experiential learning dengan siswa yang belajar dengan model pembelajaran konvensional; 2) terdapat perbedaan keterampilan berpikir kritis antara siswa yang belajar dengan model experiential learning dengan siswa yang belajar dengan model pembelajaran konvensional; 3) terdapat perbedaan motivasi berprestasi antara siswa yang belajar dengan model experiential learning dengan siswa yang belajar dengan model pembelajaran konvensional.Kata Kunci : Model Experiential Learning, Keterampilan Berpikir Kritis, Motivasi Berprestasi This quasi experimental research aimed to analyze the differences in the critical thinking skill and achievement motivation among students who learned with experiential learning model with students who learned with the conventional learning model. To achieve these objectives, the research carried out by taking the study population are students of class X MIPA SMAN 1 Semarapura, semester 2, academic year 2013/2014. Based on the results of the random sampling, class X MIPA 6 was selected as the experimental class and class X MIPA 7 as the control class. Critical thinking skill data taken with the test, and achievement motivation were taken using a questionnaire. The collected data were analyzed by descriptive and multivariate analysis. Based on the analysis of data and discussion of the obtained findings include: 1) there are differences in critical thinking skill and achievement motivation among the students who learned with the experiential learning model with students who studied with the conventional learning model; 2) there is a difference between the students\u27 critical thinking skill that learned with the experiential learning with students who learned with the conventional learning; and 3) there is a difference between the achievement motivation of students who learned with the experiential learning with students who learned with the conventional learning

Intracranial massive subdural haematoma: a potentially serious consequence of diagnostic lumbar puncture

Intracranial subdural haematoma (SDH) is an exceptionally rare complication of lumbar puncture (LP) and cerebrospinal fluid (CSF) drainage. Post LP headache mostly has a benign course, but it can also be a manifestation of a potentially life-threatening complication such as SDH. Only a few cases has been reported in literature. We report a case of massive intracranial SDH in a young male following LP and CSF drainage