Malathion Resistance in Larvae of Some Southern Minnesota Populations of the Indianmeal Moth,\u3ci\u3e Plodia Interpunctella\u3c/i\u3e (Lepidoptera: Pyralidae), Infesting Bulk-Stored Shelled Corn

Larvae of 21 field collected populations of the Indianmeal moth, Plodia interpunctella, infesting stored shelled corn in southern Minnesota were tested for their susceptibility to malathion in the laboratory. A population that was a composite of the 21 populations and a malathion susceptible population were also tested for their susceptibility to malathion, pirimiphos-methyl and chlorpyrifos-methyl. Comparison of the LDso values of the field populations with the malathion susceptible population indicated that the field populations were ca. 33- to 625-fold resistant to malathion. The composite field population was ca. 243-fold resistant to malathion, and this population was 3.2-fold cross-resistant to pirimiphos-methyl, but was highly susceptible to chlorpyrifos-methyl

Hemodialysis catheter related blood stream infections

Background: Hemodialysis catheter related blood stream infection (CRBSI) is common cause for sepsis in hemodialysis patients with high morbidity and mortality. It has to be diagnosed promptly for early treatment to avoid serious complications including catheter removal. This prospective study was undertaken to study clinical features, to validate use of cultures drawn from different sites for diagnosis and management of hemodialysis catheter related blood stream infection (CRBSI). As there is paucity of data regarding CRBSI, hence the study was undertaken.Methods: All hemodialysis patients with CRBSI between October 2016 to October 2017 were included. Variables like different catheter position, blood cultures collected from peripheral vein, both catheter hubs, catheter exit site swab, and catheter tip cultures were analyzed with respect to time to culture positivity, microbes and its management were analyzed.Results: Mean duration of hemodialysis catheter inside patient was 24days, most common risk factor for CRBSI was diabetes mellitus (58%) followed by surgery (50%), previous dialysis catheterization within preceding 2months (33%). 30% patients had history of guide wire exchange of catheters previously, most had temporary catheter (88%), most common site of catheter was right internal jugular vein (58%). Cultures showed gram positive organisms in 63%. It was found that same monomicrobial growth was noted in most cultures stating less chances of contamination. Exit site, catheter tip samples and blood sample from catheter’s venous hub yielded early result. It was found that same monomicrobial growth was noted in most cultures stating less chances of contamination. Among complications, 8% had endocarditis, 61% had catheter removal. Average hospital stay was 9days. Deferve scence was noted upon antibiotic therapy and catheter removal in most cases. Death was noted in 8% due to sepsis.Conclusions: CRBSI are major cause of admissions, morbidity and mortality in hemodialysis patients on catheters. Gram positive organisms were commonest pathogens causing CRBSI. Exit site, catheter tip samples and blood sample from catheter’s venous hub yielded early result. Peripheral blood sampling for culture diagnosing was unnecessary. Most requires 2-6weeks systemic antibiotics and catheter removal especially if persistent fever and systemic complications are present

Guidance Systems of Fighter Aircraft

Mission performance of a fighter aircraft is crucial for survival and strike capabilities in todays' aerial warfare scenario. The guidance functions of such an aircraft play a vital role inmeeting the requirements and accomplishing the mission success. This paper presents the requirements of precision guidance for various missions of a fighter aircraft. The concept ofguidance system as a pilot-in-loop system is pivotal in understanding and designing such a system. Methodologies of designing such a system are described

Structural heat treatments against Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae): effect of flour depth, life stage and floor.

The effect of high temperatures (50-60°C) and two levels of sanitation (~0.5 and 43 g of flour), on mortality of eggs, young larvae, old larvae, pupae, and adults of the red flour beetle, Tribolium castaneum, were evaluated during heat treatment of a pilot flour mill at Kansas State University. The mill was heated once during 13-14 May 2009 and once during 25-26 August 2009. Each of the heat treatments lasted 24 h. Bioassay boxes, with life stages of T. castaneum and temperature sensors confined in small compartments, were placed in 25 locations across all five mill floors. Temperature data showed that the mean time to 50°C based on the two treatments ranged from 10.39 to 17.18 h, and the mean time above 50°C ranged from 6.01 to 13.63 h. The mean maximum temperatures attained ranged from 50.7 to 61.4°C. In general, temperatures were lower in compartments with 43 g of flour when compared with compartments with 0.5 g of flour. Temperatures were also lower on the first floor than on the remaining floors. In box bioassays, essentially none of the life stages survived the 24 h heat treatment (99-100% mortality), except on the first floor. The survival of insects, especially on the first floor, is related to how quickly temperatures reached 50°C and how long temperatures were held between 50 and 60°C, and the maximum temperatures attained at a given location. There were only small differences in mortality between the two levels of sanitation. These results show that heat treatment of flour mills can control all life stages of T. castaneum in 24 h. Keywords: Tribolium castaneum, Heat treatment, Sanitation, Life stages, Methyl bromide alternative

Heat treatment: A viable methyl bromide alternative for managing stored-product insects in food-processing facilities

Heat treatment involves raising and maintaining temperatures of grain storage structures, warehouses, and food-processing facilities between 50 to 60°C to manage stored-product insect species. The duration of heat treatment is application-specific and may vary from 6 h for an empty storage facility to 24 h for an entire food-processing facility. Laboratory and commercial trials with high temperatures during the last decade, especially with forced air gas heaters, have resulted in a wealth of information on (1) understanding responses of insect species and life stages to heat, (2) heat distribution within a treated area, and (3) techniques necessary for gauging effectiveness of commercial heat treatments. Insect responses vary with the temperature, among species, and within a species among life stages. Air movement and strategic placement of fans are important for eliminating cool spots.Keywords: Heat, Forced air, Flour mills, Methyl bromide alternativ

Hypovitamanosis D and non cardiac chest pain

Background: Recurrent atypical chest pain not due to cardiac illness is a very common condition in medical outpatient departments. Authors found that people consulting for atypical chest pain often have significant Vitamin D deficiency and correction of Vitamin D deficiency relieved patient symptoms. Hence authors carried out this study.Methods: Persons aged below 50 years were taken up for study. Those attending medical clinics with complaints of chest pain occurring more than two times were taken up for study. Cardiac illness was excluded by clinical examination and investigations. Those found to have low Vitamin D were taken up for study. 60,000 international units Vitamin D was administered orally weekly for 8 weeks. They were followed up twice weekly for three months and once monthly for three months.Results: Results were analyzed and charted. 120 subjects were taken up for study and duration of study was three years. Average age of the study group was 37.50 years and the average Vitamin D level was 15.75 nanogram/ml (ngm/ml). Duration of chest pain ranged from one week to one year. Most of the patients had migratory chest pain.Conclusions: As Vitamin D deficiency is a treatable medical condition it may be prudent to check Vitamin D levels in the patients presenting with recurrent atypical pain in the chest. It reduces the burden on the health care system and relieves the suffering of the patient. It may not be futile to check Vitamin D levels even in the patients with coronary artery disease who are suffering from atypical chest pain

DESIGNING A FLYWHEEL TO GENERATE HIGHER ENERGY IN SMALL CYCLE

In machines where the procedure is intermittent like punching machines, shearing machines, riveting machines, crushers etc., the flywheel stores energy in the source of energy throughout the greater portion, from the operating cycle and provides up throughout a small duration of the cycle. Thus the power in the source of energy to machines is provided practically in a constant rate through the operation. However, the flywheel has undoubtedly the finest inertia even just in a multi cylinder engine. Apart from its principle function, the fly wheel works as a person in the friction clutch, & it always carries even the ring gear from the electric starter. ANSYS Mechanical software provides a comprehensive product solution for structural straight line/nonlinear and dynamics analysis. The merchandise provides a complete group of elements behavior, material models and equation solvers for an array of engineering problems. Additionally, ANSYS Mechanical offers thermal analysis and coupled-physics abilities involving acoustic, piezoelectric, thermal-structural and thermal-electric analysis. SolidWorks utilizes a 3D design approach. While you design a component, in the initial sketch towards the final model, you develop a 3D entity. Out of this 3D entity, you may create 2D sketches, or mate different components to produce 3D assemblies. You may also create 2D sketches of 3D assemblies