739 research outputs found
The Quantum Mechanics of Hyperion
This paper is motivated by the suggestion [W. Zurek, Physica Scripta, T76,
186 (1998)] that the chaotic tumbling of the satellite Hyperion would become
non-classical within 20 years, but for the effects of environmental
decoherence. The dynamics of quantum and classical probability distributions
are compared for a satellite rotating perpendicular to its orbital plane,
driven by the gravitational gradient. The model is studied with and without
environmental decoherence. Without decoherence, the maximum quantum-classical
(QC) differences in its average angular momentum scale as hbar^{2/3} for
chaotic states, and as hbar^2 for non-chaotic states, leading to negligible QC
differences for a macroscopic object like Hyperion. The quantum probability
distributions do not approach their classical limit smoothly, having an
extremely fine oscillatory structure superimposed on the smooth classical
background. For a macroscopic object, this oscillatory structure is too fine to
be resolved by any realistic measurement. Either a small amount of smoothing
(due to the finite resolution of the apparatus) or a very small amount of
environmental decoherence is sufficient ensure the classical limit. Under
decoherence, the QC differences in the probability distributions scale as
(hbar^2/D)^{1/6}, where D is the momentum diffusion parameter. We conclude that
decoherence is not essential to explain the classical behavior of macroscopic
bodies.Comment: 17 pages, 24 figure
Band Crossing and Novel Low-Energy Behaviour in a Mean Field Theory of a Three-Band Model on a Cu--O lattice
We study correlation effects in a three-band extended Hubbard model of Cu --
O planes within the 1/N mean field approach, in the infinite U limit. We
investigate the emerging phase diagram and discuss the low energy scales
associated with each region. With increasing direct overlap between oxygen
orbitals, , the solution displays a band crossing which, for an
extended range of parameters, lies close to the Fermi level. In turn this leads
to the nearly nested character of the Fermi surface and the resulting linear
temperature dependence of the quasi-particle relaxation rate for sufficiently
large T. We also discuss the effect of band crossing on the optical
conductivity and comment on the possible experimental relevance of our
findings.Comment: 12 pages, Latex-Revtex, 6 PostScript figures. Submitted to Phys. Rev.
Physical Controls on Carbonate Intraclasts: Modern Flat Pebbles From Great Salt Lake, Utah
In carbonateâforming environments, authigenic minerals can cement surface sediments into centimeterâsized intraclasts that are later reworked into âflatâpebbleâ or âedgewiseâ conglomerates. Flatâpebble conglomerates comprise only a small portion of facies in modern marine environments but are common in ancient strata, implying that seafloor cements were more widespread in the past. Flatâpebble conglomerates nearly disappeared after the Ordovician radiation, yet it is unclear if this decline was due to changing seawater chemistry or if increased infaunalization and bioturbation simply worked to break down nascent clasts. We discovered a process analog that produces flatâpebble conglomerates around the Great Salt Lake, Utah, USA, and studied these facies using field observations, wave models, satellite imagery, petrography, and microanalytic chemical data. Clasts were sourced from waveârippled grainstone that cemented in situ in offshore environments. Lake floor cements formed under aragonite saturation states that are lower than modern marine settings, suggesting that physical processes are at least as important as chemical ones. Results from our wave models showed that coarse sediments near the field site experience quiescent periods of up to 6 months between suspension events, allowing isopachous cements to form. Using a simple mathematical framework, we show that the main difference between Great Salt Lake and modern, lowâenergy marine settings is that the latter has enough bioturbating organisms to break up clasts. Observations from Great Salt Lake demonstrate how geologic trends in flatâpebble abundance could largely reflect changes in total infaunal biomass and ecology without requiring regionalâtoâglobal changes in seawater chemistry
Change in hematologic indices over time in pediatric inflammatory bowel disease treated with azathioprine
Azathioprine leads to changes in mean corpuscular volume (MCV) and white blood cell (WBC) indices reflecting efficacy or toxicity. Understanding the interactions between bone marrow stem cells and azathioprine could highlight abnormal response patterns as forerunners for hematologic malig-nancies. This study gives a statistical description of factors influencing the relationship between MCV and WBC in children with inflammatory bowel disease treated with azathioprine. We found that leukopenia preceded macroÂŹcytosis. Macrocytosis is therefore not a good predictor of leukopenia. Further studies will be necessary to determine the subgroup of patients at increased risk of malignancies based on bone marrow response
Physical Controls on Carbonate Intraclasts: Modern Flat Pebbles From Great Salt Lake, Utah
In carbonateâforming environments, authigenic minerals can cement surface sediments into centimeterâsized intraclasts that are later reworked into âflatâpebbleâ or âedgewiseâ conglomerates. Flatâpebble conglomerates comprise only a small portion of facies in modern marine environments but are common in ancient strata, implying that seafloor cements were more widespread in the past. Flatâpebble conglomerates nearly disappeared after the Ordovician radiation, yet it is unclear if this decline was due to changing seawater chemistry or if increased infaunalization and bioturbation simply worked to break down nascent clasts. We discovered a process analog that produces flatâpebble conglomerates around the Great Salt Lake, Utah, USA, and studied these facies using field observations, wave models, satellite imagery, petrography, and microanalytic chemical data. Clasts were sourced from waveârippled grainstone that cemented in situ in offshore environments. Lake floor cements formed under aragonite saturation states that are lower than modern marine settings, suggesting that physical processes are at least as important as chemical ones. Results from our wave models showed that coarse sediments near the field site experience quiescent periods of up to 6 months between suspension events, allowing isopachous cements to form. Using a simple mathematical framework, we show that the main difference between Great Salt Lake and modern, lowâenergy marine settings is that the latter has enough bioturbating organisms to break up clasts. Observations from Great Salt Lake demonstrate how geologic trends in flatâpebble abundance could largely reflect changes in total infaunal biomass and ecology without requiring regionalâtoâglobal changes in seawater chemistry
Random paths and current fluctuations in nonequilibrium statistical mechanics
An overview is given of recent advances in nonequilibrium statistical
mechanics about the statistics of random paths and current fluctuations.
Although statistics is carried out in space for equilibrium statistical
mechanics, statistics is considered in time or spacetime for nonequilibrium
systems. In this approach, relationships have been established between
nonequilibrium properties such as the transport coefficients, the thermodynamic
entropy production, or the affinities, and quantities characterizing the
microscopic Hamiltonian dynamics and the chaos or fluctuations it may generate.
This overview presents results for classical systems in the escape-rate
formalism, stochastic processes, and open quantum systems
Collisional cross sections and momentum distributions in astrophysical plasmas: dynamics and statistical mechanics link
We show that, in stellar core plasmas, the one-body momentum distribution
function is strongly dependent, at least in the high velocity regime, on the
microscopic dynamics of ion elastic collisions and therefore on the effective
collisional cross sections, if a random force field is present. We take into
account two cross sections describing ion-dipole and ion-ion screened
interactions. Furthermore we introduce a third unusual cross section, to link
statistical distributions and a quantum effect originated by the
energy-momentum uncertainty owing to many-body collisions, and propose a
possible physical interpretation in terms of a tidal-like force. We show that
each collisional cross section gives rise to a slight peculiar correction on
the Maxwellian momentum distribution function in a well defined velocity
interval. We also find a possible link between microscopical dynamics of ions
and statistical mechanics interpreting our results in the framework of
non-extensive statistical mechanics.Comment: 8 page
Evaluating transport in irregular pore networks
A general approach for investigating transport phenomena in porous media is presented. This approach has the capacity to represent various kinds of irregularity in porous media without the need for excessive detail or computational effort. The overall method combines a generalized effective medium approximation (EMA) with a macroscopic continuum model in order to derive a transport equation with explicit analytical expressions for the transport coefficients. The proposed form of the EMA is an anisotropic and heterogeneous extension of Kirkpatrick's EMA which allows the overall model to account for microscopic alterations in connectivity (with the locations of the pores and the orientation and length of the throat) as well as macroscopic variations in transport properties. A comparison to numerical results for randomly generated networks with different properties is given, indicating the potential for this methodology to handle cases that would pose significant difficulties to many other analytical models
Placebo response rate in clinical trials of fistulizing crohn's disease: systematic review and meta-analysis
Background & Aims: It is important to determine the magnitude and identify modifiers of the rate of response to placebo in clinical trials of fistulizing Crohnâs disease (CD), to understand disease progression, and to calculate sample size. We conducted a systematic review and meta-analysis of rates of response to placebo in trials of patients with fistulizing CD. Methods: We searched MEDLINE, EMBASE, EMBASE CLASSIC, and the Cochrane central register of controlled trials for randomized controlled trials (RCTs) comparing pharmacologic agents with placebo in adults with fistulizing CD. We identified studies that reported complete fistula closure, partial closure, or response. Data were extracted as intention-to-treat analyses and pooled by using a random-effects model. Proportions of patients who received placebo and had complete or partial fistula(e) closure were calculated, with 95% confidence intervals (CIs). The effects of trial characteristics on the magnitude of response to placebo were examined. Results: Thirteen RCTs were eligible for our analysis; these included 579 patients assigned to placebo groups. The pooled rate of response to placebo, among all RCTs, for complete fistula closure was 15.6% (95% CI, 10.9%â20.9%), with significant heterogeneity (I2 = 62.5%, P = .001). The pooled rate of response to placebo for partial fistula closure or response in 9 trials, comprising 423 patients, was 18.3% (95% CI, 14.8%â22.1%). Rates of response to placebo were significantly lower in trials with shorter durations of therapy and shorter intervals to assessment of fistula closure. Neither exposure to the pharmacologic agent during the induction phase of the same (or related) RCT nor concomitant medications had any effect. Conclusions: In a meta-analysis of rate of response to placebo in patients with fistulizing CD, we found that fistulae closed in almost 1/6 patients given placebo in RCTs of pharmacologic agents. Future research should identify characteristics of patients that predict response to placebo
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