Training Special Educators in a World of Technology Changes

Educatio

Trajectory and sighting analysis for first- apparition comets

Statistical, trajectory, and sighting analysis for first-apparition comets - flight path parameters - astronom

The Effect of Biased Communications On Both Trusting and Suspicious Voters

In recent studies of political decision-making, apparently anomalous behavior has been observed on the part of voters, in which negative information about a candidate strengthens, rather than weakens, a prior positive opinion about the candidate. This behavior appears to run counter to rational models of decision making, and it is sometimes interpreted as evidence of non-rational "motivated reasoning". We consider scenarios in which this effect arises in a model of rational decision making which includes the possibility of deceptive information. In particular, we will consider a model in which there are two classes of voters, which we will call trusting voters and suspicious voters, and two types of information sources, which we will call unbiased sources and biased sources. In our model, new data about a candidate can be efficiently incorporated by a trusting voter, and anomalous updates are impossible; however, anomalous updates can be made by suspicious voters, if the information source mistakenly plans for an audience of trusting voters, and if the partisan goals of the information source are known by the suspicious voter to be "opposite" to his own. Our model is based on a formalism introduced by the artificial intelligence community called "multi-agent influence diagrams", which generalize Bayesian networks to settings involving multiple agents with distinct goals

Methods, systems, and devices for treating tinnitus with VNS pairing

A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.Board of Regents, University of Texas Syste

Climate and Land-Use Controls on Surface Water Diversions in the Central Valley, California

California’s Central Valley (CV) is one of the most productive agricultural regions in the world, enabled by the conjunctive use of surface water and groundwater. We investigated variations in the CV’s managed surface water diversions relative to climate variability. Using a historical record (1979−2010) of diversions from 531 sites, we found diversions are largest in the wetter Sacramento basin to the north, but most variable in the drier Tulare basin to the south. A rotated empirical orthogonal function (REOF) analysis finds 72% of the variance of diversions is captured by the first three REOFs. The leading REOF (35% of variance) exhibited strong positive loadings in the Tulare basin, and the corresponding principal component time-series (RPC1) was strongly correlated (ρ > 0.9) with contemporaneous hydrologic variability. This pattern indicates larger than average diversions in the south, with neutral or slightly less than average diversions to the north during wet years, with the opposite true for dry years. The second and third REOFs (20% and 17% of variance, respectively), were strongest in the Sacramento basin and San Francisco Bay−Delta. RPC2 and RPC3 were associated with variations in agricultural- and municipal-bound diversions, respectively. RPC2 and RPC3 were also moderately correlated with 7-year cumulative precipitation based on lagged correlation analysis, indicating that diversions in the north and central portions of the CV respond to longer-term hydrologic variations. The results illustrate a dichotomy of regimes wherein diversions in the more arid Tulare are governed by year-to-year hydrologic variability, while those in wetter northern basins reflect land-use patterns and low-frequency hydrologic variations

COPD: Optimizing Treatment

A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2 In 2015, the World Health Organization updated its Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, classifying patients with COPD based on disease burden as determined by symptoms, airflow obstruction, and exacerbation history.3 These revisions, coupled with expanded therapeutic options within established classes of medications and new combination drugs to treat COPD (TABLE 1),3-6 have led to questions about interclass differences and the best treatment regimen for particular patients

Hemoglobin A1c Levels Modify Associations between Dietary Acid Load and Breast Cancer Recurrence.

BackgroundMetabolic acidosis promotes cancer metastasis. No prospective studies have examined the association between dietary acid load and breast cancer recurrence among breast cancer survivors, who are susceptible to metabolic acidosis. Hyperglycemia promotes cancer progression and acid formation; however, researchers have not examined whether hyperglycemia can modify the association between dietary acid load and breast cancer recurrence.MethodsWe studied 3081 early-stage breast cancer survivors enrolled in the Women's Healthy Eating and Living study who provided dietary information through 24-h recalls at baseline and during follow-up and had measurements of hemoglobin A1c (HbA1c) at baseline. We assessed dietary acid load using two common dietary acid load scores, potential renal acid load (PRAL) score and net endogenous acid production (NEAP) score.ResultsAfter an average of 7.3 years of follow-up, dietary acid load was positively associated with recurrence when baseline HbA1c levels were ≥ 5.6% (median level) and ≥5.7% (pre-diabetic cut-point). In the stratum with HbA1c ≥ 5.6%, comparing the highest to the lowest quartile of dietary acid load, the multivariable-adjusted hazard ratio was 2.15 (95% confidence interval [CI] 1.34-3.48) for PRAL and was 2.31 (95% CI 1.42-3.74) for NEAP. No associations were observed in the stratum with HbA1c levels were <5.6%. P-values for interactions were 0.01 for PRAL and 0.05 for NEAP.ConclusionsOur study demonstrated for the first time that even at or above normal to high HbA1c levels, dietary acid load was associated with increased risk of breast cancer recurrence among breast cancer survivors.ImpactsOur study provides strong evidence for developing specific dietary acid load guidelines based on HbA1c levels

Rosalia de Castro

Dissertation (Ph.D.)--University of Kansas, Spanish, 1961