42 research outputs found
Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice
Tests for Structural Breaks in Time Series Analysis: A Review of Recent Development
The issue related to a structural break or change point in the econometric and statistics literature is relatively vast. In recent decades it was increasing, and it got recognized by various researchers. The debates are about a structural break or parameter instability in the econometric models. Over some time, there has been a different mechanism, and theoretical development stretching the fundamental change and strengthen the econometric literature. Estimation of structural break has undergone significant changes. Instead of exploring the presence of a known structural break, now the emphasis is on tracing multiple unknown cracks using dynamic programming. The paper an attempt has been made to review the different forms of the presence of structural break(s) over the past.</jats:p
Deflection of Steel Reinforced Concrete Beam Prestressed With CFRP Bar
Carbon Fiber Reinforced polymer (CFRP) bars are weak in yielding property which results in sudden failure of structure at failure load. Inclusion of non-pretensioned steel reinforcement in the tension side of CFRP based prestressed concrete beam will balance the yielding requirements of member and it will show the definite crack failure pattern before failure. Experimental investigation has been carried out to study the deflection behavior of partially prestressed beam. Experimental works includes four beam specimens stressed by varying degree of prestressing. The Partial Prestressing Ratio (PPR) of specimen is considered for experimental works in the range of 0.6 to 0.8. A new deflection model is recommended in the present study considering the strain contribution of CFRP bar and steel reinforcement for the fully bonded member. New deflection model converges to experimental results with the error of less than 5%
Deflection of Steel Reinforced Concrete Beam Prestressed with CFRP Bar
Carbon Fiber Reinforced polymer (CFRP) bars are weak in yielding property which results in sudden failure of structure
at failure load. Inclusion of non-pretensioned steel reinforcement in the tension side of CFRP based prestressed concrete beam
will balance the yielding requirements of member and it will show the definite crack failure pattern before failure. Experimental
investigation has been carried out to study the deflection behavior of partially prestressed beam. Experimental works includes four
beam specimens stressed by varying degree of prestressing. The Partial Prestressing Ratio (PPR) of specimen is considered for
experimental works in the range of 0.6 to 0.8. A new deflection model is recommended in the present study considering the strain
contribution of CFRP bar and steel reinforcement for the fully bonded member. New deflection model converges to experimental
results with the error of less than 5%
Influence of Deformability Behavior in Prestressed Concrete Beams Using Carbon-Fiber-Reinforced Polymer Tendon
Management of root rot (<i>Macrophomina phaseolina</i>) in peanut with biocontrol agents and studying its root physiology
Dietary saturated fatty acids aggravate pressure overload-induced cardiomyopathy in mice in the absence of cardiac steatosis
Coconut Oil Aggravates Pressure Overload-Induced Cardiomyopathy without Inducing Obesity, Systemic Insulin Resistance, or Cardiac Steatosis
Studies evaluating the effects of high-saturated fat diets on cardiac function are most often confounded by diet-induced obesity and by systemic insulin resistance. We evaluated whether coconut oil, containing C12:0 and C14:0 as main fatty acids, aggravates pressure overload-induced cardiomyopathy induced by transverse aortic constriction (TAC) in C57BL/6 mice. Mortality rate after TAC was higher (p < 0.05) in 0.2% cholesterol 10% coconut oil diet-fed mice than in standard chow-fed mice (hazard ratio 2.32, 95% confidence interval 1.16 to 4.64) during eight weeks of follow-up. The effects of coconut oil on cardiac remodeling occurred in the absence of weight gain and of systemic insulin resistance. Wet lung weight was 1.76-fold (p < 0.01) higher in coconut oil mice than in standard chow mice. Myocardial capillary density (p < 0.001) was decreased, interstitial fibrosis was 1.88-fold (p < 0.001) higher, and systolic and diastolic function was worse in coconut oil mice than in standard chow mice. Myocardial glucose uptake was 1.86-fold (p < 0.001) higher in coconut oil mice and was accompanied by higher myocardial pyruvate dehydrogenase levels and higher acetyl-CoA carboxylase levels. The coconut oil diet increased oxidative stress. Myocardial triglycerides and free fatty acids were lower (p < 0.05) in coconut oil mice. In conclusion, coconut oil aggravates pressure overload-induced cardiomyopathy
