CRYSTAL GROWTH AND NON-LINEAR APPLICATION OF SULPHA DRUG-AN INVITRO ANTIBACTERIAL EFFECT AGAINST ESBL (EXTRENDED SPECTRUM OF BETA LACTAMSE)

 A probe into the literature survey clearly reveals no work has been carried out for the synthesis of 4-(Phenyl sulfonyl) morpholine and 4-(Phenyl sulfony) morpholine potassium hydrogen phosphate using TLC 4-(Phenyl sulfonyl)morpholine and 4-(Phenyl sulfony) morpholine potassium hydrogen phosphate. Aim and scope of the work is highly effective medicinal hydrazide derivatives have been synthesized from Schiff base route. The structure of the ligand THC and its complexes were carried various spectral studies. From these studies, I know about the knowledge of organic chemistry and spectroscopy. In my present work, we have to synthesis of and 4-(Phenyl sulfonyl) morpholine and 4- (Phenyl sulfony) morpholine potassium hydrogen phosphate establish the structure through the analytical (elemental and TLC) and spectral (IR, H1 NMR) methods of characterization.&nbsp

A Fingerprint Identification Approach using Neural Networks

Today, because of the vulnerability of standard authentication system, law-breaking has accumulated within the past few years. Identity authentication that relies on biometric feature like face, iris, voice, hand pure mathematics, handwriting, retina, fingerprints will considerably decrease the fraud, so that they square measure being replaced by identity verification mechanisms. Among bioscience, fingerprint systems are one amongst most generally researched and used. it\'s fashionable due to their easy accessibility. Moreover in this work the system modified to an adaptive system i.e intelligent by using neural networks

COPPER –CATALYZED ELECTROPHILIC AMINATION OF ARYLSILANES WITH HYDROXYLAMINES

A copper-catalyzed electrophilic amination of aryl((2-hydroxymethyl)phenyl)dimethylsilanes with O-acylated hydroxylamines has been createdto manage the cost of the relating anilines in great yields. The synergist response continues easily under gentle conditions and endures a wide scope of utilitarian gatherings

Fingerprint Recognition in Biometric Security -A State of the Art

Today, because of the vulnerability of standard authentication system, law-breaking has accumulated within the past few years. Identity authentication that relies on biometric feature like face, iris, voice, hand pure mathematics, handwriting, retina, fingerprints will considerably decrease the fraud. so that they square measure being replaced by identity verification mechanisms. Among bioscience, fingerprint systems are one amongst most generally researched and used. it\'s fashionable due to their easy accessibility. during this paper we tend to discuss the elaborated study of various gift implementation define strategies together with their comparative measures and result analysis thus as realize a brand new constructive technique for fingerprint recognition

Influence of nitrogen salts on growth and physiological responses of Rhizophora apiculata Blume in non-aerated water culture

Influence of two different forms of nitrogen on growth and physiological aspects of water-cultured seedlings of Rhizophora apiculata was studied. Of the two forms of nitrogen supplied to the growth medium, ammonium nitrogen was better than nitrate nitrogen by exhibiting increased dry matter production, shoot length, leaf area and also enhanced the contents of carotenoids, chlorophylls and their presence in photosystems and light harvesting protein complex

Ovarian cancer: emerging concept on cancer stem cells.

Emerging evidence suggests that the capacity of a tumor to grow and propagate is dependent on a small subset of cells within a tumor, termed cancer stem cells. In fact, cancer cells, like stem cells, can proliferate indefinitely through a dysregulated cellular self-renewal capacity. Cancer stem cells may originate due to the distribution into self-renewal and differentiation pathways occurring in multi-potential stem cells, tissue-specific stem cells, progenitor cells and cancer cells. Recent studies have shown that ovarian cancer also contains stem cells or tumor-initiating cells. Moreover, ovarian serous adenocarcinomas were disaggregated and subjected to growth conditions to select for self-renewing, non-adherent spheroids previously shown to be derived from tissue stem cells. A recent study showed that epithelial ovarian cancer was derived from a sub population of CD44+, CD117+ and CD133+ cells. The existence of cancer stem cells would explain why only a small minority of cancer cells is capable of extensive proliferation of the tumor. In this review, we have discussed the studies on ovarian cancer stem cells along with the molecular pathways that could be involved in these cancer stem cells

Ovarian cancer: emerging concept on cancer stem cells

Emerging evidence suggests that the capacity of a tumor to grow and propagate is dependent on a small subset of cells within a tumor, termed cancer stem cells. In fact, cancer cells, like stem cells, can proliferate indefinitely through a dysregulated cellular self-renewal capacity. Cancer stem cells may originate due to the distribution into self-renewal and differentiation pathways occurring in multi-potential stem cells, tissue-specific stem cells, progenitor cells and cancer cells. Recent studies have shown that ovarian cancer also contains stem cells or tumor-initiating cells. Moreover, ovarian serous adenocarcinomas were disaggregated and subjected to growth conditions to select for self-renewing, non-adherent spheroids previously shown to be derived from tissue stem cells. A recent study showed that epithelial ovarian cancer was derived from a sub population of CD44+, CD117+ and CD133+ cells. The existence of cancer stem cells would explain why only a small minority of cancer cells is capable of extensive proliferation of the tumor. In this review, we have discussed the studies on ovarian cancer stem cells along with the molecular pathways that could be involved in these cancer stem cells

Enhancement of the Power Output of Photogalvanic Cells

342-34

Prognostic Significance of Bundle Branch Blocks in Acute Coronary Syndrome

INTRODUCTION: Presence of new onset bundle branch block is associated with increased mortality in patients with acute coronary syndrome (ACS). Development of new bundle branch block despite prompt fibrinolytic therapy may signify an extensive and ongoing AMI. It is associated with overall poor prognosis, and high risk for short term mortality. Presence of complete Bundle Branch Block (BBB) Left or Right in AMI patients represents an independent and very important predictor of in-hospital complication and poor survival on long term.8 Earlier studies suggested that patients with BBB have move co-morbid conditions and are less likely to receive therapies such as thrombolytics, aspirin, β blockers and have an increased in hospital mortality rates.5 In our study we evaluated the prognostic significance of different types of BBB present during the course of AMI in the hospitalized patients and we followed up the patient at the end of one month. AIM OF STUDY: 1. To estimate the prevalence of BBB in patients with Acute coronary Syndrome. 2. To compare the clinical characteristics in patients with ACS with or without BBB. 3. To assess the prognostic significance of BBB in patients with ACS depending on its form of presentation. 4. Presence of BBB in ACS could be used for risk stratification and selection of treatment according to the risk pattern. MATERIALS AND METHODS: Study Design: This study is a single centre prospective analytical study carried out in the coronary care unit, Department of Cardiology, Madras Medial College during the period of January 2009 to December 2009. Total number of patients were 150. All the patients in the study were hospitalized. No out patients were included. A detailed informed concent was obtained from the patients Our Institutional ethical committee clearance was obtained. Standard approved protocol were used for treating all the patients. The results were tabulated and analysed using chi-square test. Inclusion and Exclusion Criteria: Patients presented with ACS in the coronary care unit were included and observed. Serial ECGs of all the patients admitted with ACS in CCU were studied. CK-MB was measured in some of the cases. Since facilities for measuring. Troponin was not available we were not able to measure it. Patients demographics, clinical variables like prior MI, angina, CHF, Cardiac risk factors like DM, SHT, smoking dylipidemia chest pain on admission, Killip class, use of thrombolytic therapy, reasons for not using thrombolytic therapy were recorded. Patients were followed until discharge from the hospital and at the end of one month. During the period of follow up, events like ventricular dysfunction, arrhythmias, recurrent angina, CHF, 2°, 3° heart block, mechanical complications, cardiac arrest and death were recorded. These variables are compared between ACS patients with BBB and without BBB. Patients were excluded if presented with 1. Pre existing BBB, 2. Non Specific Intraventricular conduction defects. SUMMARY: Prognostic significance of BBB in ACS was studied in coronary care unit, Department, of cardiology. Madras Medical College, following observations were made. • Of 150 patients studied 34 (22.66%) patients had new onset BBB. • BBB patients had higher killip class (II, III, IV)/. • BBB patients had increased incidence of arrhythmias. • Higher incidence of complete heart block. • Higher incidence of death due to complete heart block was observed. • Higher incidence of systolic and diastolic LV dysfunction. • BBB was associated with higher incidence of hypotension, heart failure. • Higher percentage of in hospital death (17.6%). • Among BBB group higher incidence of Mortality was seen in bifasicular block. No difference was observed in mortality at the end of 1 month between the two groups. CONCLUSION: When physicians are called to see a patient with ACS with BBB, major diagnostic and prognostic issues should be addressed. Many studies have dealt with the aspects of this problem. Patients having new onset BBB accompanying ACS early after fibrinolytic therapy independently have higher in-hospital mortality than patient without these conducting abnormalities. Patients with RBBB are more prone to arrhythmias and heart failure. Patients with LBBB are more prone to systolic LV dysfunction. Patients with bifasicular block are more prone to complete heart block, heart failure and cardiogenic shock. Among BBB, bifasicular block is associated with higher incidence of mortality. Bunde Branch block with ACS patients had worse clinical pattern such as • Higher Killip class, • Arrhythmias, • Complete heart block, • Systolic, diastolic LV dysfunction, • Hypotension, • Heart failure. Emergency physicians and cardiologists should be familiar with the mechanisms related to BBBs and with prognostic implication of BBBs in the setting of ACS. Such knowledge constitutes an immediate available clinical tool for the management of patients with ACS, especially nowadays when the pathways to the optimal reperfusion strategy are available