Surgery during holiday periods and prognosis in oesophageal cancer: a population-based nationwide Swedish cohort study

OBJECTIVE: Previous studies indicate an increased short-term and long-term mortality from major cancer surgery performed towards the end of the working week or during the weekend. We hypothesised that the prognosis after major cancer surgery is also negatively influenced by surgery conducted during holiday periods. SETTING: Population-based nationwide Swedish cohort study. PARTICIPANTS: Patients undergoing oesophagectomy for oesophageal cancer between 1987 and 2010. Among 1820 included patients, 206 (11.3%) and 373 (20.5%) patients were operated on during narrow and wide holiday periods, respectively. INTERVENTIONS: Narrow (7 weeks) and wide (14 weeks) Swedish holiday periods. PRIMARY AND SECONDARY OUTCOME MEASURES: 90-day all-cause, 5-year all-cause and 5-year disease-specific mortality. RESULTS: Narrow holiday period did not increase all-cause 90-day (HR=0.84, 95% CI 0.53 to 1.33), all-cause 5-year (HR=1.01, 95% CI 0.85 to 1.21) or disease-specific 5-year mortality (HR=1.04, 95% CI 0.87 to 1.26). Similarly, wide holiday period did not increase the risk of 90-day (HR=0.79, 95% CI 0.55 to 1.13), all-cause 5-year (HR=0.96, 95% CI 0.84 to 1.1) or disease-specific 5-year mortality (HR=1.03, 95% CI 0.89 to 1.19). CONCLUSIONS: No measurable effects of holiday periods on short-term or longer term mortality following surgery for oesophageal cancer were observed in this population-based study, indicating that an adequate surgical experience was maintained during holiday periods

Introducing Norm Creative Perspectives in Engineering and Design Educations

The design of technologies, built environments, products, or services can result in inequalities, exclusion, and discrimination, possibly because designers–often unintentionally–reproduce social norms through their designs. This strongly relates to engineering and design educations, preparing future professionals and contributing to sustainable societies. The aim of this paper is to introduce and explore different ways to adopt such perspectives in education and training at the faculty of engineering at Lund University, LTH. Empirical materials were gathered through a literature review, discussions with critical friends and a teaching session about Universal Design for Learning (UDL) and Norm Creativity. Besides UDL, the Design Justice Framework was proposed to stimulate norm-critical thinking and thereby norm creativity in the design of new courses and as part of the education and training of future engineers and designers. The framework outlines three questions to be considered: Who participated in the design or development process?, Who benefited? and Who was harmed? As a result, we proposed teaching and learning activities, course module prototypes, on norm creative perspectives that could be adapted to different course contexts and situations. Based on this development, we discuss norm creative perspectives in relation to the benefits for students and educators, the complex social challenges in course design, and the wider ramifications of courses in engineering and design in terms of potential contributions towards the development of sustainable societies

Depending on Sex? Tongue, sieve, and ladle shaped pendants from late Iron Age Gotland

Artifacts of female dress such as brooches and pendants have long been objects of interest to scholars of late Iron Age /early medieval Scandinavia. They figure in dating and tracing stylistic developments, and their presence is often (controversially) used to help assign gender to burials. There are three types of pendants which constitute a type of feminine adornment unique to Viking Age Gotland: the so-called tongue, sieve, and ladle pendants. The purpose of this paper is to examine these pendant types and the possible symbolic and magical functions behind their forms and manner of use, and how these functions intersected with the ideologies mapped onto female bodies in Old Norse culture(s). The pendants’ appearance as fixed and incomplete sets is analyzed, and the designs of the “tongue”, “sieve” and “ladle” are located within the wider field of Iron Age iconography - particularly in association with the depiction of idealized gender roles. In conclusion a hypothesis as to why these particular amulets were used exclusively by wealthy Viking women is presented; that the tongue, sieve, and ladle pendants signaled and were involved in the construction of a particular type of elite female identity linked to specifically feminine forms of embodied power and prestige within late Iron Age society

Monte Carlo Simulation of Ising Models with Dipole Interaction

Recently, a new memory effect was found in the metamagnetic domain structure of the diluted Ising antiferromagnet $Fe_x Mg_{1-x} Cl_2$ by domain imaging with Faraday contrast. Essential for this effect is the dipole interaction. We simulate the low temperature behavior of diluted Ising-antiferromagnets by a Monte Carlo simulation considering long range interaction. The metamagnetic domain structure occurring due to the dipole interaction is investigated by graphical representation. In the model considered the antiferromagnetic state is stable for an external magnetic field smaller than a lower boundary $B_{c1}$ while for fields larger than an upper boundary $B_{c2}$ the system is in the saturated paramagnetic phase, where the spins are ferromagnetically polarized. For magnetic fields in between these two boundaries a mixed phase occurs consisting of ferromagnetic domains in an antiferromagnetic background. The position of these ferromagnetic domains is stored in the system: after a cycle in which the field is first removed and afterwards applied again the domains reappear at their original positions. The reason for this effect can be found in the frozen antiferromagnetic domain state which occurs after removing the field.Comment: Latex, 10 pages; 3 postsript-figures, compressed tar-file, uuencoded, report 10109

New, efficient, and accurate high order derivative and dissipation operators satisfying summation by parts, and applications in three-dimensional multi-block evolutions

We construct new, efficient, and accurate high-order finite differencing operators which satisfy summation by parts. Since these operators are not uniquely defined, we consider several optimization criteria: minimizing the bandwidth, the truncation error on the boundary points, the spectral radius, or a combination of these. We examine in detail a set of operators that are up to tenth order accurate in the interior, and we surprisingly find that a combination of these optimizations can improve the operators' spectral radius and accuracy by orders of magnitude in certain cases. We also construct high-order dissipation operators that are compatible with these new finite difference operators and which are semi-definite with respect to the appropriate summation by parts scalar product. We test the stability and accuracy of these new difference and dissipation operators by evolving a three-dimensional scalar wave equation on a spherical domain consisting of seven blocks, each discretized with a structured grid, and connected through penalty boundary conditions.Comment: 16 pages, 9 figures. The files with the coefficients for the derivative and dissipation operators can be accessed by downloading the source code for the document. The files are located in the "coeffs" subdirector

Quantum molecular dynamics simulations for the nonmetal-to-metal transition in fluid helium

We have performed quantum molecular dynamics simulations for dense helium to study the nonmetal-to-metal transition at high pressures. We present new results for the equation of state and the Hugoniot curve in the warm dense matter region. The optical conductivity is calculated via the Kubo-Greenwood formula from which the dc conductivity is derived. The nonmetal-to-metal transition is identified at about 1 g/ccm. We compare with experimental results as well as with other theoretical approaches, especially with predictions of chemical models.Comment: 4 pages, 5 figure

Probing the interiors of the ice giants: Shock compression of water to 700 GPa and 3.8 g/ccm

Recently there has been tremendous increase in the number of identified extra-solar planetary systems. Our understanding of their formation is tied to exoplanet internal structure models, which rely upon equations of state of light elements and compounds like water. Here we present shock compression data for water with unprecedented accuracy that shows water equations of state commonly used in planetary modeling significantly overestimate the compressibility at conditions relevant to planetary interiors. Furthermore, we show its behavior at these conditions, including reflectivity and isentropic response, is well described by a recent first-principles based equation of state. These findings advocate this water model be used as the standard for modeling Neptune, Uranus, and "hot Neptune" exoplanets, and should improve our understanding of these types of planets.Comment: Accepted to Phys. Rev. Lett.; supplementary material attached including 2 figures and 2 tables; to view attachments, please download and extract the gzipped tar source file listed under "Other formats