Quantum Double Models coupled with matter: an algebraic dualisation approach

In this paper, we constructed a new generalization of a class of discrete bidimensional models, the so called Quantum Double Models, by introduce matter qunits to the faces of the lattice that supports these models. This new generalization can be interpreted as the algebraic dual of a first, where we introduce matter qunits to the vertices of this same lattice. By evaluating the algebraic and topological orders of these new models, we prove that, as in the first generalization, a new phenomenon of quasiparticle confinement may appear again: this happens when the co-action homomorphism between matter and gauge groups is non-trivial. Consequently, this homomorphism not only classifies the different models that belong to this new class, but also suggests that they can be interpreted as a 2-dimensional restriction of the 2-lattice gauge theories.Comment: 18 pages, 8 figures; submitted to publicatio

Immunohistochemical staining of Langerhans cells in HPV-positive and HPV-negative cases of oral squamous cells carcinoma

The Human Papillomavirus (HPV) has been strongly implicated in development of some cases of oral squamous cell carcinoma (OSCC). However, the immunological system somehow reacts against the presence of this virus. Among the cells involved in such mechanism of defense Langerhans cells (LC) stand out, which are responsible for processing and presenting antigens. OBJECTIVES: The purposes of this study were to investigate the presence of HPV DNA and to evaluate the immunohistochemical reactivity for Langerhans cells between HPV-positive and HPV-negative OSCC. Twenty-seven cases of OSSC were evaluated. MATERIAL AND METHODS: DNA was extracted from paraffin-embedded tissue samples and amplified by Polymerase Chain Reaction (PCR) for the detection of HPV DNA. Viral typing was performed by dot blot hybridization. Immunohistochemistry was performed by the Streptavidin-biotin technique. RESULTS: From the 27 cases, 9 (33.3%) were HPV-positive and 18 (66.0%) HPV-negative. HPV 18 was the most prevalent viral type (100% cases) and infection with HPV-16 (co-infection) was detected in only 1 case. In the OSCC specimens examined, immunoreactivity to S-100 antibody was detected in all cases, with a mean number of 49.48±30.89 Langerhans cells positive for immunostaining. The mean number of immunostained Langerhans cells was smaller in the HPV-positive cases (38 cells/case) than in the HPV-negative cases (42.5 cells/case), but this difference was not significant (p=0.38). CONCLUSIONS: The low frequency of detection of HPV DNA in OSCC indicates a possible participation of the virus in the development and progression of only a subgroup of these tumors. There was no association between the immunohistochemical labeling for Langerhans cells (S-100+) and HPV infection of in OSSC. These findings suggest that the presence of HPV in such OSCC cases could not alter the immunological system, particularly the Langerhans cells

Analytical methodologies concerning historic neighbourhoods for urban renewal in southern chile. How to understand the place to intervene?

Historic urban spaces are emplacements that present a particular special interest due to their cultural value and their both urban and architectural pattern. The built environment of cities is composed of a number of variables "“ anthropic, spatial, morphological, environmental, social, constructive and atmospheric "“ and all of them must be part of a system that is capable of generating more comfortable and efficient environments. Currently, the work of expert professionals linked to the built environment implies an environmental challenge related to the buildings and their direct harmony with the natural environment; the development of comprehensive plans capable of administering, preserving and protecting historical-heritage constructions in areas susceptible to certain natural disasters; as well as the incorporation of sustainability criteria in urban planning instruments, which is one of the main objectives for regional and state public administrations. This research work intends to propose a comprehensive set of analytical methodologies focused on the morphology of urban blocks, the vitality of the neighbourhood and the functional service life state presented by heritage buildings in order to provide strategies for a proposal for urban regeneration in the case of Barrios Bajos of the city of Valdivia, in southern Chile. This study shows the implications of the proposed methodologies in order to verify their validity and empirically test the application of this type of proposal in one of the historic neighbourhoods of the city of Valdivia, used as a prototype of southern Chile. © 2021 The Author(s). Published by Vilnius Gediminas Technical Universit