Endoscopic management of enteral tubes in adult patients - Part 1: definitions and indications. European Society of Gastrointestinal Endoscopy (ESGE) guideline

Main recommendationsCellular mechanisms in basic and clinical gastroenterology and hepatolog

Endoscopic management of enteral tubes in adult patients - Part 2: peri- and post-procedural management. European Society of Gastrointestinal Endoscopy (ESGE) guideline

Main recommendationsCellular mechanisms in basic and clinical gastroenterology and hepatolog

L'alliance thérapeutique, objectif de la première rencontre au service des urgences

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Propagation of bovine rotavirus by cats and dogs.

SPF cats were experimentally infected orally with bovine rotavirus. All of them excreted virus over a period of at least two weeks after inoculation. Seroconversion was observed after one week for all the animals, but it did not stop viral excretion or prevent further excretion of the same or another rotavirus strain given later. Cats or dogs kept in the same cage as inoculated animals became infected and excreted virus, but seroconversion was not observed in these contact animals. None of the animals developed diarrhoea during the experiment. Cats are thus able to multiply bovine rotavirus, and transmission of this virus occurs between cats or between dogs and cats. Therefore, cats, like dogs, may play a role in the epizootiology of rotavirus infection in calves

Sclérose tubéreuse de Bourneville et polypose colique

Tuberous sclerosis is an autosomal dominant genetic disorder that is characterized by epilepsy, mental retardation and facial angiofibromas. Usually, the disease is diagnosed in childhood but there are frustrates form of tuberous sclerosis with or without genetic mutation. This clinical case about a man who is diagnosed a colonic polyposis, a rectal adenocarcinoma and a tuberous sclerosis. .SCOPUS: ar.jinfo:eu-repo/semantics/publishe

In vivo and in vitro effect of acyclovir on pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus.

The effect of various concentrations of acyclovir on the mean plaque size of pseudorabies virus (SHV), infectious bovine rhinotracheitis virus (IBR virus) and pigeon herpesvirus (PHV) has been studied. Acyclovir significantly reduced the mean plaque size of SHV and PHV, whereas IBR virus was less affected and did only show a reduction of the mean plaque size at the highest concentration of acyclovir used (1000 microM). In vivo effect of acyclovir was tested using pigeons and budgerigars experimentally infected with PHV and rabbits experimentally infected with a very low dose of SHV. Intramuscular injections of acyclovir (100 mg/kg/day; three injections/day) did not prevent the appearance of clinical disease in infected pigeons nor did reduce the level of viral excretion. The same treatment applied, as for the pigeons, before infection protected most of the budgerigars as long as they were treated, but most of them died soon after the end of the treatment. Only one rabbit was protected by the treatment. SHV was recovered in the lung of only one of the treated animals, whereas it was isolated in the lungs of each control animal

Simultaneous presence of different Borrelia burgdorferi genospecies in biological fluids of Lyme disease patients.

Oligonucleotide primers based on Borrelia burgdorferi sensu lato ospA gene sequences have been designed for use in the PCR to type all (SL primers) or each (GI to GIII primers) of the B. burgdorferi sensu lato genospecies involved in Lyme disease. These genospecies-specific primers were then used in the PCR on 24 biological fluids collected from 18 neuroborreliosis patients. Among the samples tested, 20 contained DNA from Borrelia garinii, 11 contained DNA from B. burgdorferi sensu stricto, and 10 contained DNA from Borrelia afzelii. In toto, 10 patients appeared to have been infected by a single genospecies and 8 were infected by more than one Lyme disease-associated genospecies. Serum specimens from six patients were absorbed with heterologous antigens and tested by Western blotting (immunoblotting). In four cases, residual immunodetection revealed specific epitopes of genospecies also detected by PCR; in two of them, the concordant results indicated pluri-infection of the patients. In the other two cases, Western blotting showed specific antibodies for two genospecies of Borrelia, while PCR detected DNA from only one. In summary, the data underscored the relatively high prevalence of pluri-infections in Lyme disease and confirmed the association of B. garinii with neuroborreliosis