82 research outputs found

    Occupational and public radiation safety - A legacy

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    An attempt has been made to give adequate justification for the application for a higher doctorate degree (DSc) by identifying contributions of originality and merit in three closely related fields, namely radiation dosimetry, the safe transport of radioactive materials and academic scientific publishing. The intent has been to demonstrate a sustained, consistent and substantial contribution to the advancement of knowledge in the profession of radiation protection, together with international authoritative recognition and standing over a period of many years. In the area of radiation dosimetry the main contributions have been in the standardisation of aspects of thermoluminescence dosimetry and promoting clarity in radiation dosimetry understanding and terminology. I had the honour of giving the KEYNOTE address at the 14th International Solid State Dosimetry Conference in 2004. In the area of safe transport of radioactive material contributions have been oriented towards to the developing and upgrading of the IAEA Regulations for the Safe Transport of Radioactive Materials, but in particular, in initiating and developing the Q system dosimetric modelling, leading to establishing essential quantitative control parameters for all radionuclides to be transported. The Q system still provides virtually all of the quantitative requirements of the international transport regulations, and national regulations in most countries of the world. The asests and rights of Nuclear Technology Publishing were sold to Oxford University Publiahing in 2004. In the area of academic publishing major contribution have been the establishment of Nuclear Technology Publishing., the publishing of scientific text books and the founding and publication of three highly prestigious scientific journals, namely a) Radiation Protection Dosimetry, arguably the lead world journal in the field of radiation protection. RPD will shortly enter its 40th year of publication, including 187 volumes, each of four issues, and having published papers from several thousand authors, b) The Journal of the ICRU which has recently been sold on by Oxford University Press to another publisher. c) The international journal Packaging, Transport, Storage and Security of Radioactive Materials, which reached its 25th year of publishing before publication ceased in 201

    International Stem Cell Collaboration: How Disparate Policies between the United States and the United Kingdom Impact Research

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    As the scientific community globalizes, it is increasingly important to understand the effects of international collaboration on the quality and quantity of research produced. While it is generally assumed that international collaboration enhances the quality of research, this phenomenon is not well examined. Stem cell research is unique in that it is both politically charged and a research area that often generates international collaborations, making it an ideal case through which to examine international collaborations. Furthermore, with promising medical applications, the research area is dynamic and responsive to a globalizing science environment. Thus, studying international collaborations in stem cell research elucidates the role of existing international networks in promoting quality research, as well as the effects that disparate national policies might have on research. This study examined the impact of collaboration on publication significance in the United States and the United Kingdom, world leaders in stem cell research with disparate policies. We reviewed publications by US and UK authors from 2008, along with their citation rates and the political factors that may have contributed to the number of international collaborations. The data demonstrated that international collaborations significantly increased an article's impact for UK and US investigators. While this applied to UK authors whether they were corresponding or secondary, this effect was most significant for US authors who were corresponding authors. While the UK exhibited a higher proportion of international publications than the US, this difference was consistent with overall trends in international scientific collaboration. The findings suggested that national stem cell policy differences and regulatory mechanisms driving international stem cell research in the US and UK did not affect the frequency of international collaborations, or even the countries with which the US and UK most often collaborated. Geographical and traditional collaborative relationships were the predominate considerations in establishing international collaborations

    Shotgun Proteomics Identifies Serum Fibronectin as a Candidate Diagnostic Biomarker for Inclusion in Future Multiplex Tests for Ectopic Pregnancy

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    Ectopic pregnancy (EP) is difficult to diagnose early and accurately. Women often present at emergency departments in early pregnancy with a 'pregnancy of unknown location' (PUL), and diagnosis and exclusion of EP is challenging due to a lack of reliable biomarkers. The objective of this study was to identify novel diagnostic biomarkers for EP. Shotgun proteomics, incorporating combinatorial-ligand library pre-fractionation, was used to interrogate pooled sera (n = 40) from women undergoing surgery for EP, termination of viable intrauterine pregnancy and management of non-viable intrauterine pregnancy. Western blot was used to validate results in individual sera. ELISAs were developed to interrogate sera from women with PUL (n = 120). Sera were collected at time of first symptomatic presentation and categorized according to pregnancy outcome. The main outcome measures were differences between groups and area under the receiver operating curve (ROC). Proteomics identified six biomarker candidates. Western blot detected significant differences in levels of two of these candidates. ELISA of sera from second cohort revealed that these differences were only significant for one of these candidates, fibronectin. ROC analysis of ability of fibronectin to discriminate EP from other pregnancy outcomes suggested that fibronectin has diagnostic potential (ROC 0.6439; 95% CI 0.5090 to 0.7788; P>0.05), becoming significant when 'ambiguous' medically managed PUL excluded from analysis (ROC 0.6538; 95% CI 0.5158 to 0.7918; P<0.05). Fibronectin may make a useful adjunct to future multiplex EP diagnostic tests

    Sport policy convergence: a framework for analysis

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    This is an Accepted Manuscript of an article published by Taylor & Francis Group in European Sport Management Quarterly on 30th April 2012, available online at: http://www.tandfonline.com/10.1080/16184742.2012.669390The growth in the comparative analysis of sport management processes and policy has led to an increased interest in the concept of convergence. However, the concept is too often treated as unproblematic in definition, measurement and operationalisation. It is argued in this paper that a more effective framework for examining claims of convergence is one that analyses the concept in terms of seven dimensions which can be explored through a mix of quantitative and qualitative methods of data collection. It is also argued that a deeper understanding of the process of convergence can be gained by operationalising the concept in the context of a selected range of meso-level theories of the policy process or of specific aspects of the process. The proposed analytic framework provides not only a definition of convergence but also the basis for a more nuanced investigation of hypotheses of convergence

    Political Entrepreneurship in the Field of Māori Sovereignty in Aotearoa New Zealand

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    Individual actors have the potential to shape political outcomes through creative use of opportunities. Political entrepreneurship identifies how such actors recognise and exploit opportunities, for personal or collective gain. The existing literature focuses on individuals operating within institutional settings, with less attention paid to other types of actors. In this article, I argue for an expansion of the political entrepreneurship framework, by considering individuals in the electoral and protest arenas. An examination of the field of Māori sovereignty, or tino rangatiratanga, in Aotearoa New Zealand allows exploration of prominent actors’ innovative strategies and practices. The findings highlight the actors’ reliance on identity in mobilising support within the community, to press claims. Broadening the application of political entrepreneurship demonstrates the roles of social, cultural and political capital in influencing outcomes, by identifying opportunities available to individuals embedded in the community and according to the context of the arena

    Assessment of new public management in health care: the French case

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    Leadership and Institutional Reform: Engineering Macroeconomic Policy Change in Australia

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    This article seeks to enhance the actor perspective on major policy reforms. It builds upon the literature on “policy entrepreneurs” and addresses its explanatory vagueness by specifying five hypotheses outlining the actions that proponents of major policy change need to take in order to be effective in forging departures from existing, path‐dependent policies and to overcome entrenched opposition to reforms. These hypotheses on “reformist political leadership” (after Blondel) are applied to the four attempts to reform key aspects of macroeconomic policy in Australia under the first two Labor governments led by Robert J. Hawke
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