18,535 research outputs found
Retrodiction with two-level atoms: atomic previvals
In the Jaynes-Cummings model a two-level atom interacts with a single-mode
electromagnetic field. Quantum mechanics predicts collapses and revivals in the
probability that a measurement will show the atom to be excited at various
times after the initial preparation of the atom and field. In retrodictive
quantum mechanics we seek the probability that the atom was prepared in a
particular state given the initial state of the field and the outcome of a
later measurement on the atom. Although this is not simply the time reverse of
the usual predictive problem, we demonstrate in this paper that retrodictive
collapses and revivals also exist. We highlight the differences between
predictive and retrodictive evolutions and describe an interesting situation
where the prepared state is essentially unretrodictable.Comment: 15 pages, 3 (5) figure
Economic evaluation of a nursing-led intermediate care unit
Objectives: The aim of this paper is to examine the costs of introducing a nursing-led ward program together with examining the impact this may have on patients' outcomes. Methods; The study had a sample size of 177 patients with a mean age of 77, and randomized to either a treatment group (care on a nursing-led ward, n = 97) or a control group (standard care usually on a consultant-led acute ward, n = 80). Resource use data including length of stay, tests and investigations performed, and multidisciplinary involvement in care were collected. Results: There were no significant differences in outcome between the two groups. The inpatient costs for the treatment group were significantly higher, due to the longer length of stay in this group. However, the postdischarge costs were significantly lower for the treatment group. Conclusions: The provision of nursing-led intermediate care units has been proposed as a solution to inappropriate use of acute medical wards by patients who require additional nursing rather than medical care. Whether the treatment group is ultimately cost-additive is dependent on how long reductions in postdischarge resource use are maintained
Retrodiction as a tool for micromaser field measurements
We use retrodictive quantum theory to describe cavity field measurements by
successive atomic detections in the micromaser. We calculate the state of the
micromaser cavity field prior to detection of sequences of atoms in either the
excited or ground state, for atoms that are initially prepared in the excited
state. This provides the POM elements, which describe such sequences of
measurements.Comment: 20 pages, 4(8) figure
Frictional quantum decoherence
The dynamics associated with a measurement-based master equation for quantum
Brownian motion are investigated. A scheme for obtaining time evolution from
general initial conditions is derived. This is applied to analyze dissipation
and decoherence in the evolution of both a Gaussian and a Schr\"{o}dinger cat
initial state. Dependence on the diffusive terms present in the master equation
is discussed with reference to both the coordinate and momentum
representations.Comment: 18 pages, 7 figure
Communication in quantum networks of logical bus topology
Perfect state transfer (PST) is discussed in the context of passive quantum
networks with logical bus topology, where many logical nodes communicate using
the same shared media, without any external control. The conditions under
which, a number of point-to-point PST links may serve as building blocks for
the design of such multi-node networks are investigated. The implications of
our results are discussed in the context of various Hamiltonians that act on
the entire network, and are capable of providing PST between the logical nodes
of a prescribed set in a deterministic manner.Comment: 9 pages, 1 figur
Decoherence of Quantum-Enhanced Timing Accuracy
Quantum enhancement of optical pulse timing accuracy is investigated in the
Heisenberg picture. Effects of optical loss, group-velocity dispersion, and
Kerr nonlinearity on the position and momentum of an optical pulse are studied
via Heisenberg equations of motion. Using the developed formalism, the impact
of decoherence by optical loss on the use of adiabatic soliton control for
beating the timing standard quantum limit [Tsang, Phys. Rev. Lett. 97, 023902
(2006)] is analyzed theoretically and numerically. The analysis shows that an
appreciable enhancement can be achieved using current technology, despite an
increase in timing jitter mainly due to the Gordon-Haus effect. The decoherence
effect of optical loss on the transmission of quantum-enhanced timing
information is also studied, in order to identify situations in which the
enhancement is able to survive.Comment: 12 pages, 4 figures, submitte
Cardiovascular System Studies
Contains research objectives and reports on one research project.National Institutes of Health (Grant 5 TI HE 5550-03
Relationship of serum adiponectin and resistin to glucose intolerance and fat topography in south-Asians
Objectives
South-Asians have lower adiponectin levels compared to Caucasians. It was not clear however, if this intrinsic feature is related to aspects of glucose metabolism. This study aims to determine the relationship between body fat distribution and adipocytokine in South-Asian subjects by measuring serum adipocytokines, adiposity, insulinemia, and glucose tolerance levels.
Methods
In this cross-sectional study, 150 South-Asians (80 males, 70 females) were included, 60 had NGT (Control group, Age 51.33 ± 11.5, BMI 27 ± 2.3), 60 had IGT (Age 57.7 ± 12.5, BMI 27.2 ± 2.7), 30 had type 2 DM (Age 49.5 ± 10.9, BMI 28 ± 1.7). Measures of adiposity, adipocytokines and other metabolic parameters were determined. Parameters were measured using the following: a) Plasma glucose by glucose oxidase method b) CRP by immunoturbidimetric method (Roche/Hitachi analyser) c) insulin by Medgenix INS-ELISA immunoenzymetric assay by Biosource (Belgium) d) Leptin, Adiponectin by radioimmunoassay kits by Linco Research (St. Charles MO) e) Resistin by immunoassay kits by Phoenix Pharmaceuticals INC (530 Harbor Boulevard, Belmont CA 94002, USA).
Results
Adiponectin concentrations were highest in NGT, decreased in IGT and lowest in DMT2, (both p < 0.01). Leptin was significantly higher in DMT2 than IGT and NGT p = 0.02 and 0.04 respectively. There was a significant positive relationships between log adiponectin and 2-hr insulin values, p = 0.028 and history of hypertensions and a ischemic heart disease p = 0.008 with R = 0.65. There was a significant inverse correlation between log adiponectin and resistin, p < 0.01.
Conclusion
Resistin levels had an inverse correlation with adiponectin levels, indicating an inverse relationship between pro-inflammatory cytokines and adiponectin. Adiponectin levels were related to glucose tolerance
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones-sensitive lipase in human subcutaneous abdominal adipocytes
Aim: In premenopausal women, hyper-androgenicity is associated with central obesity and an increased cardiovascular risk. We investigated the effects of dydrogesterone (DYD)(a non-androgenic progestogen) and norethisterone (NET)(an androgenic progestogen) on lipoprotein lipase (LPL), hormone-sensitive lipase (HSL) and glycerol release in adipocytes isolated from subcutaneous abdominal adipose tissue. Methods: Adipose tissue was obtained from 12 non-diabetic women, mean age 51 years (range 37-78) and mean BMI 25.4kg/m2 (range 20.3-26.4). Adipocytes were treated with increasing doses of DYD and NET for 48 hours prior to protein extraction. Effects on lipogenesis and lipolysis were assessed using western blotting to determine the expression of key enzymes, LPL (56kDa) and HSL (84kDa) respectively. Measurement of glycerol release into the medium provided an assessment of lipolytic activity. Results: Expression of LPL was increased by DYD and NET (mean protein expression relative to control ± SEM); with greatest effect at 10-8M for DYD: 2.32±0.51(p0.05). Conclusions: DYD and NET significantly increased LPL expression relative to control whilst significantly reducing HSL expression. At the concentrations studied, similar effects were observed with the androgenic NET and the non-androgenic DYD despite differing effects on the lipid profile when taken
in combination with estrogen. Further work in this area may improve knowledge about the effects of different progestogens on body fat distribution and enable progestogen use to be tailored to the individual to achieve maximal benefits
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